{
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   {
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     "elacestrant"
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     "CYCLOPHOSPHAMIDE",
     "Cyclophosphamide",
     "Frindovyx"
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   },
   {
    "disease": "neuroblastoma",
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     "Frindovyx"
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   }
  ],
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     "DABRAFENIB",
     "dabrafenib"
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   {
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     "dabrafenib"
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   },
   {
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     "dabrafenib"
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   }
  ],
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     "encorafenib"
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   },
   {
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     "encorafenib"
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   {
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     "encorafenib"
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  ],
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     "FRUQUINTINIB"
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   {
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  ],
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   },
   {
    "disease": "hepatocellular-carcinoma",
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     "ipilimumab"
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   },
   {
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   },
   {
    "disease": "lung-cancer",
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     "ipilimumab"
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     "YERVOY"
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   },
   {
    "disease": "melanoma",
    "label": "Melanoma",
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     "IPILIMUMAB",
     "ipilimumab"
    ],
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    "ot_genes": [
     "CTLA4"
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     "YERVOY"
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   }
  ],
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    "disease": "colorectal-cancer",
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     "ramucirumab"
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    "brands": [
     "CYRAMZA"
    ]
   },
   {
    "disease": "gastric-cancer",
    "label": "Gastric cancer",
    "names": [
     "RAMUCIRUMAB",
     "ramucirumab"
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   },
   {
    "disease": "hepatocellular-carcinoma",
    "label": "Hepatocellular carcinoma",
    "names": [
     "RAMUCIRUMAB",
     "ramucirumab"
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   },
   {
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    ],
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   },
   {
    "disease": "lung-cancer",
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     "ramucirumab"
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     "CYRAMZA"
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   }
  ],
  "trametinib": [
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    "disease": "colorectal-cancer",
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     "trametinib"
    ],
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    "brands": [
     "Mekinist"
    ]
   },
   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
    "names": [
     "trametinib"
    ],
    "label_role": "disease-specific",
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     "Mekinist"
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   },
   {
    "disease": "melanoma",
    "label": "Melanoma",
    "names": [
     "TRAMETINIB",
     "trametinib"
    ],
    "label_role": "disease-specific",
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     "MAP2K1"
    ],
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    "trials_active": 21,
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     "Mekinist"
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   }
  ],
  "trifluridine and tipiracil": [
   {
    "disease": "colorectal-cancer",
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     "trifluridine and tipiracil"
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    "brands": [
     "LONSURF"
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   },
   {
    "disease": "gastric-cancer",
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   }
  ],
  "irinotecan": [
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     "irinotecan"
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     "Camptosar",
     "IRINOTECAN HYDROCHLORIDE",
     "Irinotecan Hydrochloride",
     "Irinotecan hydrochloide",
     "Irinotecan hydrochloride"
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   },
   {
    "disease": "pancreatic-cancer",
    "label": "Pancreatic cancer",
    "names": [
     "irinotecan"
    ],
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    "brands": [
     "Onivyde"
    ]
   }
  ],
  "ly-3009120": [
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    "disease": "colorectal-cancer",
    "label": "Colorectal cancer",
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     "LY-3009120"
    ],
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     "BRAF"
    ],
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    "trials_active": 0
   },
   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
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     "LY-3009120"
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     "BRAF"
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    "trials_active": 0
   },
   {
    "disease": "melanoma",
    "label": "Melanoma",
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     "LY-3009120"
    ],
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     "BRAF"
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    "trials_active": 0
   }
  ],
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     "NAPORAFENIB"
    ],
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   },
   {
    "disease": "lung-cancer",
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     "NAPORAFENIB"
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     "BRAF"
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   },
   {
    "disease": "melanoma",
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     "NAPORAFENIB"
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  ],
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     "TOVORAFENIB"
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   },
   {
    "disease": "lung-cancer",
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     "TOVORAFENIB"
    ],
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     "BRAF"
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   },
   {
    "disease": "melanoma",
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     "TOVORAFENIB"
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     "BRAF"
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    "trials_active": 0
   }
  ],
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     "VEMURAFENIB"
    ],
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     "BRAF"
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    "trials_active": 4
   },
   {
    "disease": "lung-cancer",
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     "VEMURAFENIB"
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     "BRAF"
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    "trials_active": 4
   },
   {
    "disease": "melanoma",
    "label": "Melanoma",
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     "VEMURAFENIB",
     "vemurafenib"
    ],
    "label_role": "disease-specific",
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     "BRAF"
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     "ZELBORAF"
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   }
  ],
  "xl-281": [
   {
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     "XL-281"
    ],
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     "BRAF"
    ],
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    "trials_active": 0
   },
   {
    "disease": "lung-cancer",
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     "XL-281"
    ],
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     "BRAF"
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   },
   {
    "disease": "melanoma",
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     "XL-281"
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    "trials_active": 0
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  ],
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   {
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     "ENTRECTINIB"
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   {
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     "ENTRECTINIB",
     "entrectinib"
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     "ALK",
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    "brands": [
     "Rozlytrek"
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   },
   {
    "disease": "neuroblastoma",
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     "ENTRECTINIB"
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    "trials_active": 1
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  ],
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    "label": "Colorectal cancer",
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     "LAROTRECTINIB"
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    "trials_active": 2
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   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
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     "LAROTRECTINIB"
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  ],
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   {
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     "REPOTRECTINIB"
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    "trials_active": 1
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   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
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     "REPOTRECTINIB",
     "repotrectinib"
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     "NTRK1"
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    "brands": [
     "Augtyro"
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  ],
  "labetuzumab": [
   {
    "disease": "colorectal-cancer",
    "label": "Colorectal cancer",
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     "LABETUZUMAB"
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    "trials_active": 0
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   {
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     "LABETUZUMAB"
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    "trials_active": 0
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  ],
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     "lenvatinib"
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   },
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    "disease": "gastric-cancer",
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     "LENVATINIB"
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     "KDR"
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    "trials_active": 12
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   {
    "disease": "hepatocellular-carcinoma",
    "label": "Hepatocellular carcinoma",
    "names": [
     "LENVATINIB",
     "lenvatinib"
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     "KDR"
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    "trials_active": 81,
    "brands": [
     "Lenvima"
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   },
   {
    "disease": "kidney-cancer",
    "label": "Kidney cancer",
    "names": [
     "LENVATINIB",
     "lenvatinib"
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     "KDR"
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     "Lenvima"
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  ],
  "zolbetuximab": [
   {
    "disease": "gastric-cancer",
    "label": "Gastric cancer",
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     "ZOLBETUXIMAB",
     "zolbetuximab"
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    "brands": [
     "VYLOY"
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   },
   {
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     "ZOLBETUXIMAB"
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    "trials_active": 2
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  ],
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     "fluorouracil"
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     "FAVLYXA",
     "FLUOROURACIL",
     "Fluorouracil",
     "fluorouracil"
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   },
   {
    "disease": "pancreatic-cancer",
    "label": "Pancreatic cancer",
    "names": [
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    "label_role": "disease-specific",
    "ot_stage": "APPROVAL",
    "ot_genes": [
     "ALK",
     "RET"
    ],
    "trials": 46,
    "trials_active": 20,
    "brands": [
     "ALECENSA"
    ]
   },
   {
    "disease": "neuroblastoma",
    "label": "Neuroblastoma",
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     "ALECTINIB"
    ],
    "label_role": null,
    "ot_stage": "APPROVAL",
    "ot_genes": [
     "ALK"
    ],
    "trials": 1,
    "trials_active": 1
   }
  ],
  "binimetinib": [
   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
    "names": [
     "binimetinib"
    ],
    "label_role": "disease-specific",
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    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "MEKTOVI"
    ]
   },
   {
    "disease": "melanoma",
    "label": "Melanoma",
    "names": [
     "BINIMETINIB",
     "binimetinib"
    ],
    "label_role": "disease-specific",
    "ot_stage": "APPROVAL",
    "ot_genes": [
     "MAP2K1"
    ],
    "trials": 53,
    "trials_active": 21,
    "brands": [
     "MEKTOVI"
    ]
   }
  ],
  "ensartinib": [
   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
    "names": [
     "ENSARTINIB",
     "ensartinib"
    ],
    "label_role": "disease-specific",
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    "ot_genes": [
     "ALK"
    ],
    "trials": 30,
    "trials_active": 17,
    "brands": [
     "ENSACOVE"
    ]
   },
   {
    "disease": "neuroblastoma",
    "label": "Neuroblastoma",
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     "ENSARTINIB"
    ],
    "label_role": null,
    "ot_stage": "PHASE_3",
    "ot_genes": [
     "ALK"
    ],
    "trials": 2,
    "trials_active": 2
   }
  ],
  "lorlatinib": [
   {
    "disease": "lung-cancer",
    "label": "Lung cancer",
    "names": [
     "LORLATINIB",
     "lorlatinib"
    ],
    "label_role": "disease-specific",
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    "ot_genes": [
     "ALK"
    ],
    "trials": 43,
    "trials_active": 26,
    "brands": [
     "Lorbrena"
    ]
   },
   {
    "disease": "neuroblastoma",
    "label": "Neuroblastoma",
    "names": [
     "LORLATINIB"
    ],
    "label_role": null,
    "ot_stage": "APPROVAL",
    "ot_genes": [
     "ALK"
    ],
    "trials": 2,
    "trials_active": 1
   }
  ],
  "melphalan": [
   {
    "disease": "melanoma",
    "label": "Melanoma",
    "names": [
     "melphalan"
    ],
    "label_role": "backbone",
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    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "Hepzato Kit"
    ]
   },
   {
    "disease": "multiple-myeloma",
    "label": "Multiple myeloma",
    "names": [
     "melphalan"
    ],
    "label_role": "backbone",
    "ot_stage": null,
    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "EVOMELA",
     "IVRA",
     "MELPHALAN HYDROCHLORIDE",
     "Melphalan",
     "Melphalan Hydrochloride",
     "Melphalan hydrochloride"
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   }
  ],
  "zoledronic acid": [
   {
    "disease": "multiple-myeloma",
    "label": "Multiple myeloma",
    "names": [
     "zoledronic acid"
    ],
    "label_role": "backbone",
    "ot_stage": null,
    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "Zoledronic Acid",
     "Zoledronic acid",
     "zoledronic acid"
    ]
   },
   {
    "disease": "prostate-cancer",
    "label": "Prostate cancer",
    "names": [
     "zoledronic acid"
    ],
    "label_role": "backbone",
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    "ot_genes": [],
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    "trials_active": null,
    "brands": [
     "Zoledronic Acid",
     "Zoledronic acid",
     "zoledronic acid"
    ]
   }
  ],
  "niraparib": [
   {
    "disease": "ovarian-cancer",
    "label": "Ovarian cancer",
    "names": [
     "niraparib"
    ],
    "label_role": "disease-specific",
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    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "ZEJULA"
    ]
   },
   {
    "disease": "prostate-cancer",
    "label": "Prostate cancer",
    "names": [
     "niraparib"
    ],
    "label_role": "disease-specific",
    "ot_stage": null,
    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "AKEEGA"
    ]
   }
  ],
  "rucaparib": [
   {
    "disease": "ovarian-cancer",
    "label": "Ovarian cancer",
    "names": [
     "rucaparib"
    ],
    "label_role": "disease-specific",
    "ot_stage": null,
    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "Rubraca"
    ]
   },
   {
    "disease": "prostate-cancer",
    "label": "Prostate cancer",
    "names": [
     "rucaparib"
    ],
    "label_role": "disease-specific",
    "ot_stage": null,
    "ot_genes": [],
    "trials": null,
    "trials_active": null,
    "brands": [
     "Rubraca"
    ]
   }
  ],
  "amatuximab": [
   {
    "disease": "ovarian-cancer",
    "label": "Ovarian cancer",
    "names": [
     "AMATUXIMAB"
    ],
    "label_role": null,
    "ot_stage": "PHASE_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 3,
    "trials_active": 0
   },
   {
    "disease": "pancreatic-cancer",
    "label": "Pancreatic cancer",
    "names": [
     "AMATUXIMAB"
    ],
    "label_role": null,
    "ot_stage": "PHASE_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 4,
    "trials_active": 0
   }
  ],
  "anetumab ravtansine": [
   {
    "disease": "ovarian-cancer",
    "label": "Ovarian cancer",
    "names": [
     "ANETUMAB RAVTANSINE"
    ],
    "label_role": null,
    "ot_stage": "PHASE_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 3,
    "trials_active": 1
   },
   {
    "disease": "pancreatic-cancer",
    "label": "Pancreatic cancer",
    "names": [
     "ANETUMAB RAVTANSINE"
    ],
    "label_role": null,
    "ot_stage": "PHASE_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 4,
    "trials_active": 1
   }
  ],
  "ss1(dsfv)-pe38": [
   {
    "disease": "ovarian-cancer",
    "label": "Ovarian cancer",
    "names": [
     "SS1(DSFV)-PE38"
    ],
    "label_role": null,
    "ot_stage": "PHASE_1_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 2,
    "trials_active": 0
   },
   {
    "disease": "pancreatic-cancer",
    "label": "Pancreatic cancer",
    "names": [
     "SS1(DSFV)-PE38"
    ],
    "label_role": null,
    "ot_stage": "PHASE_1_2",
    "ot_genes": [
     "MSLN"
    ],
    "trials": 3,
    "trials_active": 0
   }
  ]
 }
}