{
 "disease": "prostate-cancer",
 "label": "Prostate cancer",
 "url": "https://usebiotransfer.org/disease/prostate-cancer/",
 "built": "2026-09-12",
 "facts_hash": {
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  "targets": "9b1152a95eb0"
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 "sources": {
  "targets": "Open Targets Platform GraphQL API v4",
  "trials": "ClinicalTrials.gov API v2"
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 "retrieved": {
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  "trials": "2026-09-12"
 },
 "query": {
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  "shape": "query.cond=<disease>&query.intr=<term>&pageSize=200",
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  "dedup": "by NCT id across synonyms",
  "study_types": "interventional counted in headline; observational reported separately",
  "known_floor": "trials naming an antigen only by product code are not retrieved by an intervention-name search"
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 "trials": {
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      "title": "PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores",
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      "title": "PSMA-PET: Deep Radiomic Biomarkers of Progression and Response Prediction in Prostate Cancer",
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     {
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      "title": "Single-Dose Image-Guided Radiotherapy With Urethral Sparing and DIL Boost for Intermediate-Risk Prostate Cancer (PROSINT II)",
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      "last_update": "2026-05-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04175431",
      "title": "Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study",
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      "last_update": "2026-07-07",
      "phase": "PHASE2",
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     },
     {
      "nct": "NCT04221542",
      "title": "Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04402151",
      "title": "Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer",
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      "last_update": "2026-01-26",
      "phase": "PHASE2",
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     {
      "nct": "NCT04642027",
      "title": "PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy",
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      "last_update": "2024-02-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04700332",
      "title": "PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer",
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      "last_update": "2021-07-27",
      "phase": "PHASE2",
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     {
      "nct": "NCT04794777",
      "title": "Comparing \"Salvage\" Radiotherapy and Individualized PSMA PET/CT Targeted Treatment in With Relapsing Prostate Cancer",
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      "last_update": "2025-03-20",
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     {
      "nct": "NCT04886986",
      "title": "Phase I Study of 225Ac-J591 Plus 177Lu-PSMA Small Molecule for Progressive Metastatic Castration Resistant Prostate Cancer",
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     {
      "nct": "NCT04946370",
      "title": "Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer",
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     {
      "nct": "NCT05113537",
      "title": "Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer",
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     {
      "nct": "NCT05155046",
      "title": "18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy",
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     {
      "nct": "NCT05328505",
      "title": "Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy for Prostate Cancer",
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     {
      "nct": "NCT05354375",
      "title": "Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer",
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      "last_update": "2022-04-29",
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     {
      "nct": "NCT05398302",
      "title": "Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy",
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     {
      "nct": "NCT05413850",
      "title": "Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection",
      "status": "RECRUITING",
      "last_update": "2026-05-14",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05438563",
      "title": "MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05560659",
      "title": "Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy",
      "status": "RECRUITING",
      "last_update": "2025-07-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05603559",
      "title": "177Lu-P17-087/177Lu-P17-088 in Patients With Metastatic Castration-resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-10-03",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05613894",
      "title": "Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05647564",
      "title": "PET/CT Characterization of Treatment Resistance",
      "status": "RECRUITING",
      "last_update": "2026-09-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05656573",
      "title": "CART-PSMA Cells for Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2024-11-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05691465",
      "title": "Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells",
      "status": "RECRUITING",
      "last_update": "2026-07-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05720130",
      "title": "Phase Ib/IIa Dose Escalation and Expansion Study of [\u00b2\u00b9\u00b2Pb]Pb-ADVC001 in Metastatic Prostate Cancer (TheraPb - Phase I/II Study).",
      "status": "RECRUITING",
      "last_update": "2026-02-20",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05761366",
      "title": "Application of 18F-PSMA PET / CT Imaging in Prostate Specific Membrane Antigen Positive Tumor",
      "status": "RECRUITING",
      "last_update": "2024-12-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05766371",
      "title": "Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05803941",
      "title": "Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-06-04",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05806515",
      "title": "Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation",
      "status": "RECRUITING",
      "last_update": "2026-01-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05818683",
      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05847166",
      "title": "A Phase 2/3,PSMA-T4, Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-04-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05893381",
      "title": "Lu-PSMA and Stereotactic Radiotherapy Versus Radiotherapy Alone for Prostate Cancer (LUST)",
      "status": "RECRUITING",
      "last_update": "2025-12-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05914116",
      "title": "A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors",
      "status": "RECRUITING",
      "last_update": "2025-11-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05919329",
      "title": "Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy",
      "status": "RECRUITING",
      "last_update": "2025-10-24",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05939414",
      "title": "An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.",
      "status": "RECRUITING",
      "last_update": "2026-09-01",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05948657",
      "title": "Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr",
      "status": "RECRUITING",
      "last_update": "2026-05-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06039371",
      "title": "Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06062745",
      "title": "Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT",
      "status": "RECRUITING",
      "last_update": "2025-11-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06066437",
      "title": "NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial",
      "status": "RECRUITING",
      "last_update": "2026-07-15",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06067269",
      "title": "Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial",
      "status": "RECRUITING",
      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06084338",
      "title": "Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc",
      "status": "RECRUITING",
      "last_update": "2025-12-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06095089",
      "title": "A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06099093",
      "title": "Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan",
      "status": "RECRUITING",
      "last_update": "2026-01-29",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06139575",
      "title": "Phase 1/2 Clinical Study of Lutetium Lu 177 JH020002 Injection in Patients With Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-05-13",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06145633",
      "title": "Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06216249",
      "title": "Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)",
      "status": "RECRUITING",
      "last_update": "2026-03-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06217822",
      "title": "First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "RECRUITING",
      "last_update": "2026-07-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06219746",
      "title": "99mTc-MIP-1404 SPECT/CT in Primary Staging of Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2024-01-23",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06220188",
      "title": "PSMA-RLT in Biochemically Recurrent PCa",
      "status": "RECRUITING",
      "last_update": "2024-02-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06259123",
      "title": "Neoadjuvant PSMA-RLT in Oligometastatic PCa",
      "status": "RECRUITING",
      "last_update": "2024-02-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06276465",
      "title": "Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastases Detected by Functional Imaging",
      "status": "RECRUITING",
      "last_update": "2024-12-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06288113",
      "title": "Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial",
      "status": "RECRUITING",
      "last_update": "2026-03-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06320067",
      "title": "A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-09-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06335914",
      "title": "Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-02-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06343038",
      "title": "Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study",
      "status": "RECRUITING",
      "last_update": "2024-08-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06398613",
      "title": "Preoperative PSMA PET/CT As Triage for EPLND in Patients Scheduled for RALP (PrePSMA)",
      "status": "RECRUITING",
      "last_update": "2024-12-31",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06449781",
      "title": "177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-02-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06450548",
      "title": "Dynamic 68Ga-PSMA and 18F-FDG PET/CT Analysis Prior to 177Lu-PSMA",
      "status": "RECRUITING",
      "last_update": "2026-01-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06492122",
      "title": "Study With [225Ac]Ac-FL-020 in mCRPC Participants",
      "status": "RECRUITING",
      "last_update": "2026-05-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06496581",
      "title": "Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)",
      "status": "RECRUITING",
      "last_update": "2024-12-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06508567",
      "title": "Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era",
      "status": "RECRUITING",
      "last_update": "2026-05-26",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06520345",
      "title": "The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06526299",
      "title": "Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease",
      "status": "RECRUITING",
      "last_update": "2026-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06531499",
      "title": "A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-na\u00efve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study",
      "status": "RECRUITING",
      "last_update": "2025-12-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06549465",
      "title": "Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)",
      "status": "RECRUITING",
      "last_update": "2026-07-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06568562",
      "title": "XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-06-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06574880",
      "title": "STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-05-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06600802",
      "title": "Intrinsic Validity of Molecular Marker(s) Detection on Tissular Tumoral DNA to Predict the Efficacy of 177Lutetium-PSMA-617 (Lu-PSMA) Treatment for Castration-resistant Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-12-31",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06612580",
      "title": "68Ga-AAZTA-NI-093 PET/CT: First-in-human Study",
      "status": "RECRUITING",
      "last_update": "2024-09-25",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06632977",
      "title": "Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial",
      "status": "RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06706921",
      "title": "18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2024-11-27",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06736054",
      "title": "A Phase I Trial of 61Cu-NODAGA-PSMA for Patients with Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2024-12-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06738303",
      "title": "Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06780670",
      "title": "Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy",
      "status": "RECRUITING",
      "last_update": "2026-05-27",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06798558",
      "title": "Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy",
      "status": "RECRUITING",
      "last_update": "2026-03-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06815354",
      "title": "Comprehensive Assessment of Cancer Theranostic Response",
      "status": "RECRUITING",
      "last_update": "2025-09-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06835426",
      "title": "High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins",
      "status": "RECRUITING",
      "last_update": "2025-02-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06855277",
      "title": "Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-08-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06865768",
      "title": "An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique",
      "status": "RECRUITING",
      "last_update": "2026-07-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06866938",
      "title": "Study of Re-treatment With [177Lu]Lu-PSMA in Men With Metastatic Castration Resistance Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-01-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06867588",
      "title": "The Added-value of PSMA PET in Detecting Clinically Significant Prostate Cancer Lesions in Patients Undergoing MRI-targeted Biopsy. (PANDORA)",
      "status": "RECRUITING",
      "last_update": "2025-03-31",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06906471",
      "title": "A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS",
      "status": "RECRUITING",
      "last_update": "2026-07-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06917781",
      "title": "Prostate Cancer Burden and Heterogeneity Evaluation Towards Liquid Biopsy: a Correlation Study to 18FDCFPyL PET and Patients Outcome",
      "status": "RECRUITING",
      "last_update": "2025-11-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06931340",
      "title": "Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial",
      "status": "RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06942104",
      "title": "Imaging of Solid Tumors Using 18F-TRX",
      "status": "RECRUITING",
      "last_update": "2026-07-23",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06943495",
      "title": "Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)",
      "status": "RECRUITING",
      "last_update": "2025-09-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06970119",
      "title": "A Multicenter, Open-label, Non-randomized Phase I/IIa Clinical Trial to Evaluate INR102 Injection in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-01-07",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06972628",
      "title": "Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617",
      "status": "RECRUITING",
      "last_update": "2025-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07015138",
      "title": "Comprehensive Versus Primary Tumor Radiotherapy in Oligometastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-08-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07052214",
      "title": "PSMA PET Combined With MRI for the Detection of PCa",
      "status": "RECRUITING",
      "last_update": "2026-07-23",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07054346",
      "title": "Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07056790",
      "title": "Research on the Application of 68Ga-PSMA-CYC PET Imaging in the Diagnosis, Staging, and Restaging of Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-07-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07082920",
      "title": "A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07096128",
      "title": "A Study of [177Lu] Lu-PSMA-XT Injection in Patients With Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-07-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07115277",
      "title": "Diagnostic Efficacy and Safety of Flotufolastat F-18 Injection in Subjects With Biochemical Recurrence of Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-08-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07115914",
      "title": "PSMA PET for Surveillance After Focal Therapy",
      "status": "RECRUITING",
      "last_update": "2026-02-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07142967",
      "title": "Trial Evaluating the Safety and Efficacy Of MR-Linac-Guided Radiotherapy as Salvage Treatment After External Beam Radiotherapy Recurrence (TUMORNATOR II)",
      "status": "RECRUITING",
      "last_update": "2026-07-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07145177",
      "title": "177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-06-01",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07189871",
      "title": "177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors",
      "status": "RECRUITING",
      "last_update": "2026-03-27",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07200830",
      "title": "Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial",
      "status": "RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07206056",
      "title": "An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)",
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      "last_update": "2026-08-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07210086",
      "title": "Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)",
      "status": "RECRUITING",
      "last_update": "2026-01-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07219147",
      "title": "177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-04-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07226986",
      "title": "A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-08-18",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07237269",
      "title": "Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07258407",
      "title": "A Clinical Trial Evaluating the Safety of TD001 In Patients With PSMA-Expressing Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07298239",
      "title": "An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "RECRUITING",
      "last_update": "2026-01-22",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07316686",
      "title": "Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate Adenocarcinoma",
      "status": "RECRUITING",
      "last_update": "2026-08-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07354594",
      "title": "External Beam and Radioligand Radiotherapy for mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-09-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07393867",
      "title": "Androgen-responsive POSLUMA-guided Intra-prostatic Boost",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07426055",
      "title": "PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07426094",
      "title": "PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07455903",
      "title": "Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT",
      "status": "RECRUITING",
      "last_update": "2026-08-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07468903",
      "title": "Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-05-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07476001",
      "title": "Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07537010",
      "title": "3D1015 Injection for Patients With mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-04-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07542379",
      "title": "The Safety, Dosimetry and Efficacy of 177Lu-FC516 in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07559201",
      "title": "Theranostic Applications of Radionuclides in Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-04-30",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07562438",
      "title": "Prospective Clinical Trial of 177Lu-P17-088 in the Treatment of Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-05-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07567521",
      "title": "A Study of TRC003 in the Treatment of Patients With Progressive PSMA-positive mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07569926",
      "title": "Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence",
      "status": "RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07590934",
      "title": "Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-27",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07608848",
      "title": "First-in-human Diagnostic Imaging Profile of the Theranostic Pair [68Ga]Ga-DOTA-STR-17126 and Low Dose [177Lu] Lu-DOTA-STR-17126 in Patients With Advanced or Metastatic Cancer",
      "status": "RECRUITING",
      "last_update": "2026-06-10",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07621692",
      "title": "Exploring Auger-Enhanced PSMA-Targeted Radioligand Therapy: A First-in-Taiwan Clinical Study of 161Tb-PSMA-I&T",
      "status": "RECRUITING",
      "last_update": "2026-06-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07660211",
      "title": "Clinical Evaluation of 177Lu-PSMA-VG01 Injection in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer \uff08mCRPC\uff09",
      "status": "RECRUITING",
      "last_update": "2026-06-22",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07661641",
      "title": "A Study of [177Lu]Lu-A9-0631 and [225Ac]Ac-A9-0642 With [68Ga]Ga-A9-6217 or [177Lu]Lu-A9-0631 Imaging in GRPR+ Solid Tumors",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07698535",
      "title": "Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial",
      "status": "RECRUITING",
      "last_update": "2026-08-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00005992",
      "title": "Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy",
      "status": "UNKNOWN",
      "last_update": "2013-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00043212",
      "title": "Study of a Drug [DCVax (tm)-Prostate] to Treat Prostate Cancer When Hormone Therapy is no Longer Effective.",
      "status": "WITHDRAWN",
      "last_update": "2013-05-01",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00081172",
      "title": "Radiolabeled Monoclonal Antibody in Treating Patients With Progressive Metastatic Androgen-Independent Adenocarcinoma (Cancer) of the Prostate",
      "status": "COMPLETED",
      "last_update": "2013-07-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00096629",
      "title": "Vaccine Therapy in Treating Patients With Kidney Cancer",
      "status": "COMPLETED",
      "last_update": "2018-04-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00195039",
      "title": "Treatment With Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-J591) in Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-10-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00441571",
      "title": "Safety Study of a Radiolabeled Antibody (7E11) in Patients With Progressive Hormone Refractory Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2007-09-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00538668",
      "title": "Radioimmunotherapy in Prostate Cancer Using 177Lu-J591 Antibody",
      "status": "COMPLETED",
      "last_update": "2021-03-19",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00562315",
      "title": "FACBC PET/CT for Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00705835",
      "title": "Vaccine Therapy of Prostate Cancer Patients With Recombinant Soluble Prostate-Specific Membrane Antigen (Rs-PSMA) Plus the Immunological Adjuvant Alhydrogel",
      "status": "COMPLETED",
      "last_update": "2012-01-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00712829",
      "title": "Study to Evaluate the Safety, Pharmacokinetics, Tissue Distribution, Metabolism and Dosimetry of Two Prostate Cancer Imaging Agents",
      "status": "COMPLETED",
      "last_update": "2011-10-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00859781",
      "title": "177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00916123",
      "title": "Docetaxel/Prednisone Plus Fractionated 177Lu- J591 Antibody for Metastatic, Castrate-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01140373",
      "title": "Adoptive Transfer of Autologous T Cells Targeted to Prostate Specific Membrane Antigen (PSMA) for the Treatment of Castrate Metastatic Prostate Cancer (CMPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01261754",
      "title": "A Study of 99mTc-MIP-1404 and 99mTc-MIP-1405 in Patients With Metastatic Prostate Adenocarcinoma and Healthy Volunteers",
      "status": "COMPLETED",
      "last_update": "2015-11-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01359189",
      "title": "Evaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-09-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01394042",
      "title": "Prostate Cancer Imaging With Radioactive Tracer and Ultrasound Detector Compared to MRI and ProstaScint",
      "status": "UNKNOWN",
      "last_update": "2011-07-14",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01414283",
      "title": "Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-11-01",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01414296",
      "title": "Extended Study of Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-11-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01417182",
      "title": "Biodistribution and Pharmacokinetic Study of 18F-DCFBC Prostate Specific Membrane Antigen Based PET in Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-01-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01695044",
      "title": "A Study of PSMA ADC in Subjects With Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "COMPLETED",
      "last_update": "2017-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01815515",
      "title": "Evaluation of 18F-DCFBC PSMA-based PET Imaging for Detection of Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-08-20",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01856933",
      "title": "BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM)",
      "status": "COMPLETED",
      "last_update": "2021-11-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01929239",
      "title": "Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning",
      "status": "SUSPENDED",
      "last_update": "2016-06-17",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02020135",
      "title": "An Open-label Extension Study of PSMA ADC 2301 in mCRPC",
      "status": "COMPLETED",
      "last_update": "2017-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02048150",
      "title": "Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02190279",
      "title": "18F-DCFBC PET/CT in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-04-23",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02202447",
      "title": "Phase 1 of EC1169 In Patients With Recurrent MCRPC",
      "status": "COMPLETED",
      "last_update": "2019-02-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02262910",
      "title": "Study of ES414 in Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02282137",
      "title": "68Ga-PSMA PET-CT Scan for Diagnosis and Management of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2020-08-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02410577",
      "title": "89Zr-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients With Glioblastoma Multiforme",
      "status": "COMPLETED",
      "last_update": "2019-03-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02552394",
      "title": "J591 in Patients With Advanced Prostate Cancer and Unfavorable Circulating Tumor Cell Counts",
      "status": "COMPLETED",
      "last_update": "2023-04-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02615067",
      "title": "Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-04-10",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02678351",
      "title": "68Ga-PSMA-11 PET/MRI in Finding Tumors in Patients With Intermediate or High-Risk Prostate Cancer Undergoing Surgery",
      "status": "COMPLETED",
      "last_update": "2022-03-04",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02699424",
      "title": "Prospective Evaluation of 68-Ga-prostate Specific Membrane Antigen (PSMA)-Positron Emission Tomograph (PET) and Early Prostatic Specific Antigen (PSA) Kinetics During Salvage Radiotherapy for Personalizing the Management of Men With Relapse of Prostate Cancer After Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2020-05-27",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02710422",
      "title": "Miami Membrane for Potency (MMEP) Trial",
      "status": "TERMINATED",
      "last_update": "2019-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02916537",
      "title": "A Phase 1 Trial for Evaluation of the Safety, Pharmacokinetics, and [18F] Radiation Dosimetry of CTT1057",
      "status": "COMPLETED",
      "last_update": "2017-11-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02918357",
      "title": "Gallium-68 PSMA-11 PET in Patients With Biochemical Recurrence",
      "status": "COMPLETED",
      "last_update": "2019-12-02",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02919111",
      "title": "Gallium-68 PSMA-11 PET in Intermediate to High-risk Preprostatectomy Patients",
      "status": "COMPLETED",
      "last_update": "2020-12-10",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02940262",
      "title": "Gallium Ga 68-labeled PSMA-11 PET/CT in Detecting Recurrent Prostate Cancer in Patients After Initial Therapy",
      "status": "COMPLETED",
      "last_update": "2021-07-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02952469",
      "title": "Biodistribution/Reproducibility Ga-68 PSMA-HBED-CC",
      "status": "COMPLETED",
      "last_update": "2024-09-03",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03042312",
      "title": "Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy",
      "status": "TERMINATED",
      "last_update": "2021-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03042468",
      "title": "Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-09-17",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03187990",
      "title": "Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men With Elevated PSA",
      "status": "COMPLETED",
      "last_update": "2021-09-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03204123",
      "title": "PSMA PET Imaging of Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03207139",
      "title": "Ga-68 PSMA Ligand: A Radiopharmaceutical for Localization of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03223064",
      "title": "Accuracy of Lymph Node Imaging in Prostate Cancer: PSMA PET-CT and Nano-MRI",
      "status": "UNKNOWN",
      "last_update": "2017-07-21",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03232164",
      "title": "PSMA-based 18F-DCFPyL PET/CT and PET/MRI Pilot Studies in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-12-12",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03313726",
      "title": "The Effect of ADT on PSMA-PET.",
      "status": "UNKNOWN",
      "last_update": "2017-10-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03315871",
      "title": "Combination Immunotherapy in Biochemically Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-06-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03344822",
      "title": "Place of 68Ga-PSMA-11 PET-CT in the Therapeutic Decision at the End of the Initial Staging for High Risk Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2017-11-17",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03353740",
      "title": "Gallium-68 PSMA-11 Positron Emission Tomography (PET) Imaging in Patients With Biochemical Recurrence",
      "status": "COMPLETED",
      "last_update": "2021-10-21",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03362359",
      "title": "Ga-68-PSMA-11 in High-risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-07-27",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03368547",
      "title": "68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery",
      "status": "COMPLETED",
      "last_update": "2023-04-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03392428",
      "title": "A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03403595",
      "title": "177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2018-01-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03427476",
      "title": "CTT1057, a Small Molecular Inhibitor of PSMA, as a Novel Imaging Agent of Neovascularization in Renal Cell Carcinoma",
      "status": "COMPLETED",
      "last_update": "2019-04-22",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03429244",
      "title": "PSMA-PET for Biopsy and Treatment Guidance in Primary Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03443609",
      "title": "Study of 68Ga-HBED-PSMA PET/CT and Conventional Imaging in Occult Biological Relapse Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-21",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03453528",
      "title": "Investigation of PSMA PET/CT as an Imaging Biomarker in Solid Tumors",
      "status": "COMPLETED",
      "last_update": "2025-01-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03454750",
      "title": "Radiometabolic Therapy (RMT) With 177Lu PSMA 617 in Advanced Castration Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2025-01-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03463889",
      "title": "Gallium-68 Prostate Specific Membrane Antigen PET in Diagnosing Patients With Thyroid Cancer",
      "status": "TERMINATED",
      "last_update": "2021-06-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03471650",
      "title": "Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03486886",
      "title": "PSMA-PET Imaging in Patients With Metastatic Prostate Cancer: Institutional Evaluation of Detection Yield Performance and Reproducibility",
      "status": "COMPLETED",
      "last_update": "2020-07-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03490032",
      "title": "68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa)",
      "status": "COMPLETED",
      "last_update": "2020-11-17",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03490838",
      "title": "177Lu-PSMA-R2 in Patients With PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-05-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03497377",
      "title": "Evaluation of 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2020-05-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03511664",
      "title": "Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-01-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03515577",
      "title": "Gallium Ga 68-labeled PSMA-11 PET/CT and Fluciclovine F18 PET/CT in Imaging Participants With Recurrent Prostate Cancer After Surgery",
      "status": "COMPLETED",
      "last_update": "2020-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03535831",
      "title": "PSMA PET Registry (18F-DCFPyL)",
      "status": "COMPLETED",
      "last_update": "2026-02-03",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03537391",
      "title": "Novel Imaging in Staging of Primary Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-05-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03545165",
      "title": "177Lu-J591 and 177Lu-PSMA-617 Combination for mCRPC",
      "status": "TERMINATED",
      "last_update": "2021-08-24",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03582774",
      "title": "Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03596710",
      "title": "Image-Guided Biopsies in Identifying Mechanisms of Resistance in Participants With Metastatic Castration Resistant Prostate Cancer Undergoing Radioligand Therapy",
      "status": "WITHDRAWN",
      "last_update": "2020-07-23",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03604757",
      "title": "68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Prostate Cancer Imaging According to Various Metastatic Risks",
      "status": "COMPLETED",
      "last_update": "2026-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03606837",
      "title": "68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Intermediate Risk Prostate Cancer Imaging",
      "status": "COMPLETED",
      "last_update": "2026-07-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03617588",
      "title": "68Ga-THP-PSMA PET/CT Imaging in High Risk Primary Prostate Cancer or Biochemical Recurrence of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-06-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03658447",
      "title": "PRINCE (PSMA-lutetium Radionuclide Therapy and ImmuNotherapy in Prostate CancEr)",
      "status": "COMPLETED",
      "last_update": "2023-07-28",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03675451",
      "title": "PSMA Imaging of Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03692663",
      "title": "Study of Anti-PSMA CAR NK Cell (TABP EIC) in Metastatic Castration-Resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-08-01",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03698370",
      "title": "Gallium Ga 68 DOTA-NeoBOMB1 and Gallium Ga 68 PSMA-R2 PET/MRI in Diagnosing Participants With Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-01-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03724747",
      "title": "Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Antitumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate Alone and in Combination With Darolutamide, in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-11-08",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03739684",
      "title": "Study of 18F-DCFPyL PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-06-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03762759",
      "title": "Fluciclovine F18 or Ga68-PSMA PET/CT to Enhance Prostate Cancer Outcomes",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03780075",
      "title": "Lu177-EB-PSMA617 Radionuclide Treatment in Patients With Metastatic Castration-resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-05-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03792841",
      "title": "Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC",
      "status": "TERMINATED",
      "last_update": "2025-10-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03795207",
      "title": "Prostate Cancer With OligometaSTatic Relapse: Combining Stereotactic Ablative Radiotherapy and Durvalumab (MEDI4736)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03803475",
      "title": "Gallium-68 PSMA-11 PET Imaging in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2021-08-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03805594",
      "title": "177Lu-PSMA-617 and Pembrolizumab in Treating Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-02-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03822845",
      "title": "Evaluating the Clinical Accuracy of Gallium-68 PSMA PET/CT Imaging in Patients With Biochemical Recurrence of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-04-17",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03822871",
      "title": "A Trial of CTT1403 for Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-03-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03828838",
      "title": "Lutetium-177-PSMA-617 in Low Volume Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-11-14",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03874884",
      "title": "177Lu-PSMA-617 Therapy and Olaparib in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-05-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03876912",
      "title": "The Effect of ADT on PSMA Expression in Metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2021-04-13",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03939689",
      "title": "I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).",
      "status": "COMPLETED",
      "last_update": "2025-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03949517",
      "title": "68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU Therapy",
      "status": "COMPLETED",
      "last_update": "2024-01-30",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03976843",
      "title": "Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03995888",
      "title": "Assessing Radio-hybrid Prostate Specific Membrane Antigen (rhPSMA-7.3) (18F) in Healthy Volunteers and Subjects With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04050215",
      "title": "68GA-PSMA-11 PET/CT Scan in Impacting Treatment Strategies for Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-09-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04053842",
      "title": "Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-03-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04085991",
      "title": "Two TraCer PositROn EmiSSion Tomography ComBination for Efficacy EstimatiOn of Prostate Specific Membrane Antigen Radioligand Therapy in Patients With Metastatic Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-04-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04086966",
      "title": "PSMA-PET/MRI for Radiation Treatment Planning in Patients With Locally Metastatic Prostate Cancer: A Pilot Study",
      "status": "COMPLETED",
      "last_update": "2024-04-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04147494",
      "title": "Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-21",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04154280",
      "title": "Combination of 68Ga-PSMA PET Data With Magnetic Resonance Spectroscopy Data (MRS) for Evaluating Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2019-11-06",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04186819",
      "title": "Imaging Study to Investigate the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) in Newly Diagnosed Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2025-02-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04188587",
      "title": "177Lu-PSMA-I\uff06T PSMA Radioligand Therapy in Metastatic Castration-Resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2019-12-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04216134",
      "title": "68Ga-PSMA-11 PET for the Diagnosis of Biochemically Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-06-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04225910",
      "title": "Clinical Trial of Ac225-PSMA Radioligand Therapy of Metastatic Castration-resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2020-01-13",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04227275",
      "title": "A Study of CART-PSMA-TGF\u03b2RDN in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04249947",
      "title": "P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)",
      "status": "TERMINATED",
      "last_update": "2025-02-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04279561",
      "title": "Effect of Androgen Receptor Signaling Inhibitors on 68Ga-PSMA-11 PET/CT Imaging in Patients With Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2022-09-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04282824",
      "title": "Impact of Monosodium Glutamate on 68GA-PSMA-11, PET Imaging Biodistribution in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-12-02",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04297410",
      "title": "177Lu-PSMA-I&T Prior to Radical Prostatectomy for Locally Advanced Disease",
      "status": "UNKNOWN",
      "last_update": "2020-03-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04302454",
      "title": "Androgen Deprivation Therapy for Oligo-recurrent Prostate Cancer in Addition to radioTherapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-04-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04324983",
      "title": "Identification of Predictive Biomarkers",
      "status": "COMPLETED",
      "last_update": "2023-04-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04343885",
      "title": "In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-07-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04419402",
      "title": "Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04424654",
      "title": "Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy",
      "status": "COMPLETED",
      "last_update": "2022-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04430192",
      "title": "Dosimetry, Safety and Potential Benefit of 177Lu-PSMA-617 Prior to Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2024-11-08",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04443062",
      "title": "Lutetium-177-PSMA-617 in Oligo-metastatic Hormone Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04506567",
      "title": "Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-19",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04509557",
      "title": "[177Lu]Ludotadipep Treatment in Patients With Metastatic Castration-resistant Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2022-10-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04576871",
      "title": "Re-treatment 225Ac-J591 for mCRPC",
      "status": "COMPLETED",
      "last_update": "2025-08-28",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04588454",
      "title": "18F-PSMA PET/CT for Visualization of Glioblastoma Multiforme",
      "status": "UNKNOWN",
      "last_update": "2021-01-27",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04597411",
      "title": "Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04599699",
      "title": "Integrated Boost to the Dominant Intraprostatic Nodule Based on Ga-68 PSMA PET/MR Study of SBRT With Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2020-10-23",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04619069",
      "title": "Intermittent Androgen Deprivation Therapy With or Without Stereotactic Body Radiotherapy for Molecularly Identified Hormone Sensitive Oligometastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04631601",
      "title": "Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2026-08-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04644822",
      "title": "Safety and Efficacy of [18F]PSMA-1007 Injection in Suspected Persistent or Recurrent Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2024-02-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04647526",
      "title": "Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04662580",
      "title": "ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04663997",
      "title": "177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04685811",
      "title": "Evaluation of PSMA Antagonist Produced by Two Different Methods",
      "status": "COMPLETED",
      "last_update": "2022-09-22",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04689828",
      "title": "177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04693169",
      "title": "[Al18F]PSMA137 PET/CT Imaging for PSMA-Positive Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2024-01-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04716725",
      "title": "68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04720157",
      "title": "An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-08",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04726033",
      "title": "64Cu-TLX592 Phase I Safety, PK, Biodistribution and Dosimetry Study (CUPID Study)",
      "status": "COMPLETED",
      "last_update": "2024-05-01",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04727736",
      "title": "18F-DCFPyL Positron Emission Tomography (PET) in Intermediate or High Risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-02-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04740034",
      "title": "A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma",
      "status": "TERMINATED",
      "last_update": "2025-06-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04742972",
      "title": "Prostate PMSABR Study",
      "status": "WITHDRAWN",
      "last_update": "2022-12-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04745871",
      "title": "Diagnostic Performance of PSMA PET/CT for Pre-operative Lymph Node Assessment in Intermediate and High-risk Non-metastasic Prostate Cancer (PREOP-PSMA ).",
      "status": "TERMINATED",
      "last_update": "2026-06-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04777071",
      "title": "An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04786847",
      "title": "177Lu-DOTA-TLX591 Safety, Biodistribution and Dosimetry Study",
      "status": "COMPLETED",
      "last_update": "2024-02-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04790968",
      "title": "Combined PSMA PET/MRI for Detection of Lymph Node Metastases in High-risk Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2024-11-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04796467",
      "title": "68Ga-P16-093 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2022-08-09",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04832958",
      "title": "Imaging Guided Surgery to Improve the Detection of Lymph Node Metastases in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2025-03-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04876651",
      "title": "The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only",
      "status": "TERMINATED",
      "last_update": "2026-02-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04928820",
      "title": "68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy",
      "status": "TERMINATED",
      "last_update": "2022-10-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04936334",
      "title": "The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04978675",
      "title": "An Investigational Scan (rh PSMA 7.3 PET/MRI) for the Detection of Recurrent Disease and Aid in Radiotherapy Planning in Biochemically Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-10-23",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04996602",
      "title": "Therapeutic Efficiency and Response to 2.0 GBq (55mCi) 177Lu-EB-PSMA in Patients With mCRPC",
      "status": "UNKNOWN",
      "last_update": "2022-07-15",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05022576",
      "title": "Robotic-arm Assisted Ga-68 PSMA PET/CT Guided Transgluteal Prostate Biopsy",
      "status": "COMPLETED",
      "last_update": "2021-08-26",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05034562",
      "title": "Gallium-68 PSMA-11 PET in Participants With Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2024-03-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05053152",
      "title": "Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05079698",
      "title": "A Study of Stereotactic Body Radiotherapy and 177Lu-PSMA-617 for the Treatment of Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05109884",
      "title": "Comparison of PET Imaging Patterns With PSMA and AR Expression in Prostate Cancer and Bladder Cancer",
      "status": "COMPLETED",
      "last_update": "2023-03-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05114746",
      "title": "Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan",
      "status": "COMPLETED",
      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05146973",
      "title": "External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)",
      "status": "COMPLETED",
      "last_update": "2024-12-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05150236",
      "title": "EVOLUTION: 177Lu-PSMA Therapy Versus 177Lu-PSMA in Combination With Ipilimumab and Nivolumab for Men With mCRPC",
      "status": "UNKNOWN",
      "last_update": "2023-12-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05160597",
      "title": "Image-Guided (68Ga-PSMA-11 PET/CT) Prostate Biopsy for the Diagnosis of Prostate Cancer in Men With Prior Negative/Inconclusive Biopsy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-12",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05162573",
      "title": "EBRT + Lu-PSMA for N1M0 Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-12-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05197257",
      "title": "68Ga-PSMA-11 PET in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-11-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05204927",
      "title": "177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05219500",
      "title": "Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST).",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05230251",
      "title": "Radioligand fOr locAl raDiorecurrent proStaTe cancER",
      "status": "COMPLETED",
      "last_update": "2025-09-12",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05232578",
      "title": "Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2022-08-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05286840",
      "title": "64Cu-SAR-bisPSMA Positron Emission Tomography of Patients With Known or Suspected Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-03-18",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05297162",
      "title": "PSMA PET/CT vs. mpMRI in Patients With a High Suspicion of Prostate Cancer: a Head to Head, Parallel, Prospective Trial",
      "status": "UNKNOWN",
      "last_update": "2022-04-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05340374",
      "title": "Cabazitaxel in Combination With 177Lu-PSMA-617 in Metastatic Castration-resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-04-06",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05383079",
      "title": "Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men with Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-02-07",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05441501",
      "title": "A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-03-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05448404",
      "title": "A Head-to-head Comparative Study of 18F-PSMA-1007 PET/CT and 18F-FDG PET/CT Imaging in Multiple Myeloma",
      "status": "UNKNOWN",
      "last_update": "2022-07-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05458544",
      "title": "[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application",
      "status": "UNKNOWN",
      "last_update": "2024-04-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05489991",
      "title": "A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2023-08-18",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05496959",
      "title": "177-Lutetium-PSMA Before Stereotactic Body Radiotherapy for the Treatment of Oligorecurrent Prostate Cancer, The LUNAR Study",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05522257",
      "title": "PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell Carcinomas",
      "status": "COMPLETED",
      "last_update": "2024-12-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05534594",
      "title": "Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer",
      "status": "COMPLETED",
      "last_update": "2025-06-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05547061",
      "title": "A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Dosimetry, and Anti-tumor Activity of Ga-68-NGUL / Lu-177-DGUL in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Refractory to Standard Therapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2024-12-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05547386",
      "title": "68Ga-PSMA-11 PET/CT Screening Prior to 177Lu-PSMA-617 Therapy for Patients With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-07-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05570994",
      "title": "177Lu-HTK03170 in mCRPC With PSMA Positive Disease",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2026-01-08",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05579184",
      "title": "[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application_2",
      "status": "UNKNOWN",
      "last_update": "2024-04-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05613738",
      "title": "177Lu-PSMA-EB-01 in Patients With Metastatic Castration-resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-07-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05613842",
      "title": "Copper-64 SAR Bombesin in PSMA Negative Prostate Cancer (BOP)",
      "status": "COMPLETED",
      "last_update": "2023-09-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05623878",
      "title": "68Ga-labeled NY108 PET Imaging in Patients",
      "status": "UNKNOWN",
      "last_update": "2022-12-01",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05633160",
      "title": "64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT)",
      "status": "TERMINATED",
      "last_update": "2025-08-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05658003",
      "title": "A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05670106",
      "title": "A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC",
      "status": "COMPLETED",
      "last_update": "2026-06-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05676463",
      "title": "MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-03-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05680675",
      "title": "Dual-Tracer Theranostic PET",
      "status": "COMPLETED",
      "last_update": "2025-02-06",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05682443",
      "title": "ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-22",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05683964",
      "title": "Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-13",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05732948",
      "title": "PD-1 Silent PSMA/PSCA Targeted CAR-T for the Treatment of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-11-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05733351",
      "title": "Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-09-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05744115",
      "title": "Ga-68-PSMA-11 in Men With Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-02-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05806853",
      "title": "PET/MR for Prostate Cancer Restaging: a Phase II Prospective Monocentric Study",
      "status": "COMPLETED",
      "last_update": "2023-04-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05815316",
      "title": "18F-PSMA PET/MRI for the Diagnosis of Clinically Significant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2025-04-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05815394",
      "title": "177Lu-labeled NY108 SPECT Imaging in Patients",
      "status": "UNKNOWN",
      "last_update": "2023-04-18",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05820724",
      "title": "PSMA PET Scan and mpMRI for Prostate Cancer Detection",
      "status": "UNKNOWN",
      "last_update": "2023-04-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05823402",
      "title": "Use of SPECT-CT for Comparison of Dosimetry Methods in PSMA-targeted Radioligand Therapy (SPECTacular Study)",
      "status": "UNKNOWN",
      "last_update": "2023-05-03",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05836623",
      "title": "A Phase I Study to Assess PSMA+ and PSMA- Tumour Lesions",
      "status": "UNKNOWN",
      "last_update": "2024-02-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05841992",
      "title": "Al18F-PSMA-617 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2023-05-03",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05849298",
      "title": "A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05896371",
      "title": "A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-03-30",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05900973",
      "title": "A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05902247",
      "title": "Actium-225-Prostate Specific Membrane Antigen Imaging & Therapy",
      "status": "UNKNOWN",
      "last_update": "2023-06-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05924672",
      "title": "Efficacy of Ra-223 in PSMA PET Optimally Selected Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05955677",
      "title": "Head-to-head Comparison of [68Ga]Ga-PSMA-D5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis",
      "status": "UNKNOWN",
      "last_update": "2023-07-21",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05960578",
      "title": "Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05983198",
      "title": "Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06004661",
      "title": "Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06050239",
      "title": "Study of 177Lu-PSMA-0057 in Metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-09-22",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06052306",
      "title": "A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06054789",
      "title": "Clinical Study on 68Ga-PSMA-33 for PET/CT Imaging of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-09-26",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06081686",
      "title": "Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-05-03",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06101927",
      "title": "Molecular Imaging of Prostate-Specific Membrane Antigen Using Labeled Technetium-99m BQ0413",
      "status": "COMPLETED",
      "last_update": "2026-06-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06105918",
      "title": "Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients With Biochemically Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06129851",
      "title": "Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2023-11-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06136377",
      "title": "Evaluation of the Concordance Between Pre-therapy Dosimetry Performed From 68Ga-PSMA-11 Dynamic PET and Post-treatment Dosimetry of 177Lu-PSMA-617 Vectorized Internal Radiotherapy in Patients With Metastatic Prostate Cancer Resistant to Hormonal Castration.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2023-11-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06199453",
      "title": "The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients with ACC- an Open, Non-commercial Clinical Trial",
      "status": "WITHDRAWN",
      "last_update": "2025-02-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06200103",
      "title": "Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer",
      "status": "SUSPENDED",
      "last_update": "2026-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06201741",
      "title": "A Study to Evaluate the Human Biodistribution and Dosimetry of the Radionuclide Labeled ZT-111 in Patients With Metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-01-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06228404",
      "title": "Clinical Study of Safety and Efficacy of Enhanced PSMA CAR- T in Refractory CRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-23",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06235099",
      "title": "Copper Cu 64 PSMA I&T PET Imaging in Men With Suspected Recurrence of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06237491",
      "title": "The Safety and Dosimetry Study of 177Lu-LNC1003 Injection",
      "status": "UNKNOWN",
      "last_update": "2024-07-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06241391",
      "title": "Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas",
      "status": "UNKNOWN",
      "last_update": "2024-02-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06250244",
      "title": "177Lu-LNC1011 in Patients with Metastatic Castration-resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-12-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06303713",
      "title": "LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-08",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06329830",
      "title": "177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2024-09-19",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06359821",
      "title": "Evaluate Safety, Whole-Body Distribution and Radiation Dosimetry in Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-02-14",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06377683",
      "title": "Clinical Evaluation of 177Lu-DansyI-PSMA (LNC1011) in Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-04-01",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06379217",
      "title": "NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06383052",
      "title": "A Phase 1/2 Study of 177Lu-NYM032 Injection in mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-05-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06384222",
      "title": "Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06388369",
      "title": "Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-03-13",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06433063",
      "title": "Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment",
      "status": "UNKNOWN",
      "last_update": "2024-05-29",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06437496",
      "title": "68Ga-AAZTA-093 PET/CT: First-in-human Study",
      "status": "UNKNOWN",
      "last_update": "2024-05-31",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06441994",
      "title": "Clinical Trial of Targeted Alpha Therapy Using [At-211]PSMA-5 for Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06484361",
      "title": "PET/MRI to Stage Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2024-07-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06516510",
      "title": "A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto\u00ae) in Patients With Non-curative Metastatic Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-09-25",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06546527",
      "title": "Study of [177Lu]Lu-PSMA-137 In Metastatic Castrate Resistant Prostate Cancer\uff08mCRPC\uff09",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2024-08-09",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06641219",
      "title": "Clinical Evaluation of [177Lu]Lu-BQ7876 for Targeting of Prostate-Specific Membrane Antigen",
      "status": "COMPLETED",
      "last_update": "2026-06-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06723665",
      "title": "The Exploration of 18F-PSMA-1007 PET/CT Imaging in Prostate Cancer Patients",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2025-01-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06809426",
      "title": "Evaluating the Safety and Efficacy of 177Lu-LNC1011 Injection in a Single-Center, Single-Arm, Open Study in Patients with Prostate-Specific Membrane Antigen (PSMA)-Positive Metastatic Desmoplasia-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-02-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06849544",
      "title": "Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection",
      "status": "COMPLETED",
      "last_update": "2026-08-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06881823",
      "title": "Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC",
      "status": "WITHDRAWN",
      "last_update": "2025-12-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06894511",
      "title": "An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06909825",
      "title": "FPI-2265 (225Ac-PSMA-I&T) and Olaparib for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06941480",
      "title": "A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06964958",
      "title": "177LuPSMA in Renal Cell Carcinoma",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06982222",
      "title": "Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones",
      "status": "WITHDRAWN",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07024030",
      "title": "Safety and Efficacy Trial of a Targeted PSMA Fluorescent Contrast Agent (DGPR1008) for Intraoperative Imaging of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07025512",
      "title": "177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia",
      "status": "WITHDRAWN",
      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07047118",
      "title": "A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07069465",
      "title": "Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging",
      "status": "COMPLETED",
      "last_update": "2025-07-16",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07090369",
      "title": "Phase Ib Trial of 177Lu-PSMA-I&T Therapy in Combination With Olaparib and Pembrolizumab in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-07-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07101354",
      "title": "Research on PSMA-Targeted Intraoperative Fluorescent Imaging Agents",
      "status": "COMPLETED",
      "last_update": "2025-08-03",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07162779",
      "title": "Evaluation of [68Ga]DOTA-IR-780-C-4 in PET Imaging Studies for PSMA-Positive Prostate Cancer Patients",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2025-09-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07209865",
      "title": "68Ga-P16-093 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI",
      "status": "COMPLETED",
      "last_update": "2026-07-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07214961",
      "title": "Study of Alpha Radioligand Therapy AB001 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07236112",
      "title": "Study of TRDC002 in the Diagnosis of Patients With PSMA-positive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07244393",
      "title": "Lutetium (177Lu) DGUL Combined With Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-11-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07268794",
      "title": "CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07310355",
      "title": "68Ga-PSMA-0057 and 177Lu-PSMA-0057 in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-30",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07387510",
      "title": "PSMA-Targeted Intraoperative Fluorescent Imaging Agents (DGPR1008): Validation Across Different Time Windows",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-02-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07415135",
      "title": "Safety and Efficacy of PSMA-Targeted Fluorescent Contrast Agent DGPR1008 for Intraoperative Imaging in Robot-Assisted Radical Prostatectomy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-02-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07441837",
      "title": "Terbium 161 PSMA in Lutetium-177 PSMA Naive Patients",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07550517",
      "title": "PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07587814",
      "title": "Impact of Body Composition on Dosimetry of 177Lu-PSMA Radioligand Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-05-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07593079",
      "title": "Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07609225",
      "title": "Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-02",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07623460",
      "title": "Zanzalintinib Efficacy Post Pluvicto\u00ae in Chemotherapy Na\u00efve Metastatic Castration Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07635524",
      "title": "A Phase 2 Trial of 61Cu-NU101 PET/CT Compared Against Current Standard-of-care 18F-piflufolastat (Pylarify\u00ae) PET/CT.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07636707",
      "title": "QLF4113 in Participants With Metastatic Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07639801",
      "title": "68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07650240",
      "title": "Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07674771",
      "title": "Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-24",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07677566",
      "title": "177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized Prostate Cancer: a Prospective, Single-arm, Multi-center Clinical Trial",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-01",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07682649",
      "title": "Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07711002",
      "title": "Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA \u2265 0.2 ng/mL (EvoPAR-PR05)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07725523",
      "title": "Safety and Efficacy of OTL78 (Zopocianine)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07733908",
      "title": "Effectiveness of Posluma PET Scan for Post-Treatment Monitoring of Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07737925",
      "title": "LuX: Xaluritamig in Participants With Metastatic Castrate Resistant Prostate Cancer and Suboptimal Response to Lutetium 177 Vipivotide Tetraxetan",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07747493",
      "title": "68Ga-PSMA-11 PET/MRI for Selecting Men With Prostate Cancer for Focal Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07765940",
      "title": "Safety and Preliminary Diagnostic Performance of [\u2076\u2074Cu]Cu-RAX301 in Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07766486",
      "title": "Prospective Study on the Role of Radical Prostatectomy in Oligo-metastatic Hormone-sensitive Prostate Cancer in Patients on Androgen Deprivation Therapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07795268",
      "title": "Study to Evaluate the Efficacy and Safety of 177Lu-NYM032 Injection in Participants With Progressive, PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07813637",
      "title": "Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     }
    ],
    "cell_therapy": {
     "n": 10,
     "n_observational": 0,
     "n_active": 4,
     "n_withdrawn": 0,
     "trials": [
      {
       "nct": "NCT05354375",
       "title": "Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer",
       "status": "RECRUITING",
       "last_update": "2022-04-29",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT05656573",
       "title": "CART-PSMA Cells for Advanced Prostate Cancer",
       "status": "RECRUITING",
       "last_update": "2024-11-15",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT07298239",
       "title": "An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC)",
       "status": "RECRUITING",
       "last_update": "2026-01-22",
       "phase": "EARLY_PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT01140373",
       "title": "Adoptive Transfer of Autologous T Cells Targeted to Prostate Specific Membrane Antigen (PSMA) for the Treatment of Castrate Metastatic Prostate Cancer (CMPC)",
       "status": "ACTIVE_NOT_RECRUITING",
       "last_update": "2026-07-07",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT01929239",
       "title": "Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning",
       "status": "SUSPENDED",
       "last_update": "2016-06-17",
       "phase": "PHASE1/PHASE2",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT03692663",
       "title": "Study of Anti-PSMA CAR NK Cell (TABP EIC) in Metastatic Castration-Resistant Prostate Cancer",
       "status": "UNKNOWN",
       "last_update": "2022-08-01",
       "phase": "EARLY_PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT04227275",
       "title": "A Study of CART-PSMA-TGF\u03b2RDN in Patients With Metastatic Castration Resistant Prostate Cancer",
       "status": "TERMINATED",
       "last_update": "2023-08-21",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT04249947",
       "title": "P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)",
       "status": "TERMINATED",
       "last_update": "2025-02-17",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT05489991",
       "title": "A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
       "status": "TERMINATED",
       "last_update": "2023-08-18",
       "phase": "PHASE1/PHASE2",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT05732948",
       "title": "PD-1 Silent PSMA/PSCA Targeted CAR-T for the Treatment of Prostate Cancer",
       "status": "UNKNOWN",
       "last_update": "2023-11-29",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      }
     ]
    },
    "synonyms_searched": [
     "PSMA",
     "FOLH1",
     "prostate-specific membrane antigen",
     "lutetium-177",
     "177Lu-PSMA",
     "Pluvicto",
     "PSMA-617"
    ]
   },
   "PSCA": {
    "n": 12,
    "n_observational": 1,
    "n_active": 6,
    "n_withdrawn": 0,
    "trials": [
     {
      "nct": "NCT05805371",
      "title": "PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06193486",
      "title": "Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-03-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07543055",
      "title": "A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07641049",
      "title": "Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-06-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02092948",
      "title": "Phase I Study to evaluate124I-A11 PSCA Minibody in Patients With Metastatic Prostate, Bladder and Pancreatic Cancer",
      "status": "COMPLETED",
      "last_update": "2020-07-27",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02163317",
      "title": "Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-05-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02744287",
      "title": "Safety and Activity Study of PSCA-Targeted CAR-T Cells (BPX-601) in Subjects With Selected Advanced Solid Tumors",
      "status": "TERMINATED",
      "last_update": "2026-02-23",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03579654",
      "title": "Study of Proscavax Vaccine in Patients With Localized Prostate Cancer vs Active Surveillance",
      "status": "UNKNOWN",
      "last_update": "2019-03-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03600350",
      "title": "pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03873805",
      "title": "PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03927573",
      "title": "Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker",
      "status": "TERMINATED",
      "last_update": "2023-07-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05732948",
      "title": "PD-1 Silent PSMA/PSCA Targeted CAR-T for the Treatment of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-11-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     }
    ],
    "cell_therapy": {
     "n": 8,
     "n_observational": 0,
     "n_active": 5,
     "n_withdrawn": 0,
     "trials": [
      {
       "nct": "NCT05805371",
       "title": "PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer",
       "status": "RECRUITING",
       "last_update": "2026-08-21",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT06193486",
       "title": "Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC",
       "status": "RECRUITING",
       "last_update": "2026-03-31",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT07543055",
       "title": "A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread",
       "status": "RECRUITING",
       "last_update": "2026-08-28",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT07641049",
       "title": "Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer",
       "status": "RECRUITING",
       "last_update": "2026-06-11",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT02744287",
       "title": "Safety and Activity Study of PSCA-Targeted CAR-T Cells (BPX-601) in Subjects With Selected Advanced Solid Tumors",
       "status": "TERMINATED",
       "last_update": "2026-02-23",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT03873805",
       "title": "PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer",
       "status": "ACTIVE_NOT_RECRUITING",
       "last_update": "2026-06-02",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT03927573",
       "title": "Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker",
       "status": "TERMINATED",
       "last_update": "2023-07-10",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT05732948",
       "title": "PD-1 Silent PSMA/PSCA Targeted CAR-T for the Treatment of Prostate Cancer",
       "status": "UNKNOWN",
       "last_update": "2023-11-29",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      }
     ]
    },
    "synonyms_searched": [
     "PSCA",
     "prostate stem cell antigen"
    ]
   },
   "STEAP1": {
    "n": 11,
    "n_observational": 3,
    "n_active": 10,
    "n_withdrawn": 0,
    "trials": [
     {
      "nct": "NCT04221542",
      "title": "Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06236139",
      "title": "Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06613100",
      "title": "Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07140900",
      "title": "Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07213674",
      "title": "A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-na\u00efve Metastatic Castration-resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07493512",
      "title": "Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05617040",
      "title": "Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer",
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      "last_update": "2025-11-10",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06555796",
      "title": "Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06691984",
      "title": "Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)",
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      "last_update": "2026-05-15",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07737925",
      "title": "LuX: Xaluritamig in Participants With Metastatic Castrate Resistant Prostate Cancer and Suboptimal Response to Lutetium 177 Vipivotide Tetraxetan",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07803653",
      "title": "IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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       "nct": "NCT06236139",
       "title": "Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer",
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       "last_update": "2026-08-11",
       "phase": "PHASE1/PHASE2",
       "study_type": "INTERVENTIONAL"
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      {
       "nct": "NCT07803653",
       "title": "IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer",
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      "nct": "NCT05652686",
      "title": "A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)",
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     {
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      "title": "Efficacy and Safety Evaluation of Tarlatamab in Advanced Extrapulmonary Neuroendocrine Carcinoma Patients",
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      "nct": "NCT07006727",
      "title": "Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors",
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      "last_update": "2026-09-09",
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      "nct": "NCT07111507",
      "title": "A Study of Tarlatamab for People With Prostate Cancer",
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      "last_update": "2026-08-31",
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     {
      "nct": "NCT07488923",
      "title": "A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)",
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     {
      "nct": "NCT02709889",
      "title": "Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors",
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      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04471727",
      "title": "A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)",
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      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04702737",
      "title": "A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06941480",
      "title": "A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate",
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      "last_update": "2026-08-06",
      "phase": "PHASE1",
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     {
      "nct": "NCT07052760",
      "title": "Imaging of Solid Tumors Using DLL3 SPECT",
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      "last_update": "2026-04-29",
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      "title": "A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors",
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      "title": "A Study of MGC026 in Participants With Advanced Solid Tumors",
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      "last_update": "2026-08-11",
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     {
      "nct": "NCT06863272",
      "title": "A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)",
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     {
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      "title": "A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)",
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      "nct": "NCT07181473",
      "title": "A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors",
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     {
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      "title": "177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors",
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     {
      "nct": "NCT07503808",
      "title": "A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types",
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     {
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      "title": "Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors",
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      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07581184",
      "title": "A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-07-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02628535",
      "title": "Safety Study of MGD009 in B7-H3-expressing Tumors",
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      "last_update": "2022-02-08",
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      "study_type": "INTERVENTIONAL"
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     {
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      "title": "MGC018 With or Without MGA012 in Advanced Solid Tumors",
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      "title": "A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)",
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      "phase": "PHASE1/PHASE2",
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     {
      "nct": "NCT05293496",
      "title": "A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors",
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      "last_update": "2025-10-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07802704",
      "title": "A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)",
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      "last_update": "2026-09-03",
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      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
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      "last_update": "2026-08-28",
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     {
      "nct": "NCT06095089",
      "title": "A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer",
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     {
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      "title": "A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer",
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     {
      "nct": "NCT07164443",
      "title": "A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)",
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      "last_update": "2026-08-28",
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      "nct": "NCT07225946",
      "title": "A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-08-28",
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     {
      "nct": "NCT07319871",
      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07746713",
      "title": "A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer",
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      "last_update": "2026-08-31",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00773773",
      "title": "Combination of Serum Measurements of Molecular Biomarkers and Serum Protein Profiling Can be Used to Predict Which Patients Undergoing Prostatic Biopsy Will be Diagnosed With Cancer",
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      "last_update": "2024-09-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04116164",
      "title": "Safety and Targeting of Anti-hk2 Antibody in mCRPC",
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     {
      "nct": "NCT04644770",
      "title": "A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer",
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     {
      "nct": "NCT04898634",
      "title": "A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05022849",
      "title": "A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants",
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      "last_update": "2026-04-17",
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      "nct": "NCT02391051",
      "title": "Focal Brachytherapy in Patients With Selected \"Low-risk\" Prostate Cancer - a Phase-II-trial",
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      "last_update": "2017-08-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT03495427",
      "title": "PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores",
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      "last_update": "2026-03-02",
      "phase": "PHASE2/PHASE3",
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     },
     {
      "nct": "NCT04249154",
      "title": "Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer",
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      "last_update": "2025-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04363164",
      "title": "Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression",
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      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04402151",
      "title": "Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer",
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      "last_update": "2026-01-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05393791",
      "title": "Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC",
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      "last_update": "2024-11-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05469269",
      "title": "Cleveland African American Prostate Cancer Project",
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      "last_update": "2026-04-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05574647",
      "title": "Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer",
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      "last_update": "2025-07-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05629494",
      "title": "Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test",
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      "last_update": "2024-10-18",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05647564",
      "title": "PET/CT Characterization of Treatment Resistance",
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      "last_update": "2026-09-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05806515",
      "title": "Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation",
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      "last_update": "2026-01-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05847166",
      "title": "A Phase 2/3,PSMA-T4, Prostate Cancer",
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      "last_update": "2026-04-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05919329",
      "title": "Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy",
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      "last_update": "2025-10-24",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05939414",
      "title": "An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.",
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      "last_update": "2026-09-01",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05948657",
      "title": "Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr",
      "status": "RECRUITING",
      "last_update": "2026-05-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06001619",
      "title": "Prostate Medication, Metabolism and Gut Microbiota",
      "status": "RECRUITING",
      "last_update": "2023-08-21",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06216249",
      "title": "Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)",
      "status": "RECRUITING",
      "last_update": "2026-03-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06267729",
      "title": "Study of AZD0754 in Participants With Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-02-23",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06288113",
      "title": "Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial",
      "status": "RECRUITING",
      "last_update": "2026-03-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06450106",
      "title": "Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy",
      "status": "RECRUITING",
      "last_update": "2026-02-19",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06582628",
      "title": "Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer: (TEAM PC)",
      "status": "RECRUITING",
      "last_update": "2024-12-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06592924",
      "title": "Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
      "status": "RECRUITING",
      "last_update": "2026-07-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06617481",
      "title": "PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence",
      "status": "RECRUITING",
      "last_update": "2024-10-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06824818",
      "title": "Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients",
      "status": "RECRUITING",
      "last_update": "2025-10-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06943495",
      "title": "Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)",
      "status": "RECRUITING",
      "last_update": "2025-09-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07055165",
      "title": "Connect2Care: Prostate Cancer Education and Screenings for African American Men",
      "status": "RECRUITING",
      "last_update": "2025-09-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07190300",
      "title": "TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)",
      "status": "RECRUITING",
      "last_update": "2026-06-23",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07200830",
      "title": "Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial",
      "status": "RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07210086",
      "title": "Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)",
      "status": "RECRUITING",
      "last_update": "2026-01-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07259213",
      "title": "A Study of Terbium 161 (161Tb)-RAD402 in Participants With CRPC",
      "status": "RECRUITING",
      "last_update": "2026-04-01",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07282808",
      "title": "Focal or Radical Therapy: a Lesion-based Molecular Evaluation in Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-01-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07369570",
      "title": "Evolution of Lesions in Repeated Biparametric Prostate Magnetic Resonance Imaging",
      "status": "RECRUITING",
      "last_update": "2026-02-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07393867",
      "title": "Androgen-responsive POSLUMA-guided Intra-prostatic Boost",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07426055",
      "title": "PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07426094",
      "title": "PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07567521",
      "title": "A Study of TRC003 in the Treatment of Patients With Progressive PSMA-positive mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07569926",
      "title": "Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence",
      "status": "RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07621692",
      "title": "Exploring Auger-Enhanced PSMA-Targeted Radioligand Therapy: A First-in-Taiwan Clinical Study of 161Tb-PSMA-I&T",
      "status": "RECRUITING",
      "last_update": "2026-06-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07698535",
      "title": "Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial",
      "status": "RECRUITING",
      "last_update": "2026-08-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07711314",
      "title": "Adjuvant Rezvilutamide Monotherapy for High-Risk Prostate Cancer After Radical Prostatectomy",
      "status": "RECRUITING",
      "last_update": "2026-07-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07762911",
      "title": "Evaluation of an MRI-based Prostate Cancer Screening Program (VISIONING): 5-Year Follow-up Round (VISIONING III)",
      "status": "RECRUITING",
      "last_update": "2026-08-13",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00001266",
      "title": "A Phase II Trial of Leuprolide + Flutamide + Suramin in Untreated Poor Prognosis Prostate Carcinoma",
      "status": "COMPLETED",
      "last_update": "2008-03-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00001382",
      "title": "A Phase I Study of Recombinant Vaccinia Virus That Expresses Prostate Specific Antigen in Adult Patients With Adenocarcinoma of the Prostate",
      "status": "COMPLETED",
      "last_update": "2008-03-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00002540",
      "title": "Screening for Prostate Cancer in Older Patients (PLCO Screening Trial)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00002651",
      "title": "SWOG-9346, Hormone Therapy in Treating Men With Stage IV Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-04-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00003367",
      "title": "Diet and PSA Levels in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-06-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00003653",
      "title": "Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-06-23",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00003871",
      "title": "PSA Vaccine Therapy in Treating Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-06-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00004211",
      "title": "Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-03-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00004635",
      "title": "Thalidomide for the Treatment of Hormone-Dependent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-05-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00005039",
      "title": "Vaccine Therapy in Treating Patients With Advanced Adenocarcinoma of the Prostate (Prostate Cancer)",
      "status": "TERMINATED",
      "last_update": "2013-01-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00020254",
      "title": "Vaccine Therapy Plus Sargramostim and Interleukin-2 Compared With Nilutamide Alone in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-04-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00031746",
      "title": "Soy Protein Supplement in Preventing Prostate Cancer in Patients With Elevated Prostate-Specific Antigen Levels",
      "status": "COMPLETED",
      "last_update": "2016-07-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00045227",
      "title": "Vaccine Therapy With or Without Docetaxel in Treating Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-06-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00054574",
      "title": "Monoclonal Antibody Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00058214",
      "title": "Perifosine in Treating Patients With Recurrent Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2015-02-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00060528",
      "title": "Sequential Vaccinations in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2017-10-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00068731",
      "title": "Lycopene in Treating Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-07-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00076531",
      "title": "Clinical Trial for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2008-01-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00081601",
      "title": "Study of CEP-701 in Treatment of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-08-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00082134",
      "title": "Study of ILX651 in Patients With Hormone-Refractory Prostate Cancer Previously Treated With Docetaxel",
      "status": "COMPLETED",
      "last_update": "2015-03-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00090363",
      "title": "ZD4054 (Zibotentan) in Pain-free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)",
      "status": "COMPLETED",
      "last_update": "2013-01-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00090545",
      "title": "A Phase II Study of BAY 43-9006 (Sorafenib) in Metastatic, Androgen-Independent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-06-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00106418",
      "title": "A Research Study for Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-11-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00108732",
      "title": "A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-06-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00109811",
      "title": "Vaccine Therapy in Treating Patients With Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-01-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00110162",
      "title": "Androgen Deprivation Therapy in Treating Patients With Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2013-08-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00121238",
      "title": "Cilengitide in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-04-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00136487",
      "title": "Celecoxib (Celebrex) Versus Placebo in Men With Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2009-12-09",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00138008",
      "title": "Trial to Evaluate Radiotherapy Followed by Endocrine Therapy Vs Endocrine Therapy Alone for PSA Failure After Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2016-09-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00148772",
      "title": "Study of Erlotinib in Patients With Non-Metastatic Prostate Cancer With a Rising Prostate Specific Antigen (PSA) on Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2011-06-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00165399",
      "title": "Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment",
      "status": "COMPLETED",
      "last_update": "2018-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00178113",
      "title": "A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia",
      "status": "COMPLETED",
      "last_update": "2015-05-27",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00201916",
      "title": "Shorter Radiation Schedule for the Treatment of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2010-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00207649",
      "title": "Shared Decision Making: Prostate Cancer Screening",
      "status": "COMPLETED",
      "last_update": "2024-10-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00220194",
      "title": "A Six-Month, Open-Label, Crossover Study Of the Maintenance Of Serum Testosterone And PSA Suppression After Switching Between Lupron 22.5 Mg And Eligard 22.5 Mg Or Zoladex 10.8 Mg And Eligard 22.5 Mg In Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-10-14",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00242567",
      "title": "Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-05-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00243321",
      "title": "High Dose-Rate Brachytherapy and/or Intensity Modulated External Beam Radiation Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-07-13",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00258765",
      "title": "Adjuvant Docetaxel-Zoledronic Acid in High-risk Early Prostate Cancer Following Prostatectomy.",
      "status": "TERMINATED",
      "last_update": "2010-04-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00269555",
      "title": "Effects of GCP on Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2010-06-29",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00283062",
      "title": "Adjuvant Leuprolide With or Without Docetaxel in High Risk Prostate Cancer After Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2012-01-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00304759",
      "title": "PROFIT - Prostate Fractionated Irradiation Trial",
      "status": "COMPLETED",
      "last_update": "2017-07-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00307294",
      "title": "Thalidomide and Doxil\u00ae in Patients With Androgen Independent Prostate Cancer (AIPC)",
      "status": "COMPLETED",
      "last_update": "2017-11-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00336934",
      "title": "Pomegranate Extract in Treating Patients With Rising Prostate-Specific Antigen Levels After Surgery or Radiation Therapy for Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2011-08-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00378690",
      "title": "A Phase IIIb Study of Intermittent Versus Continuous Hormone Deprivation Treatment With ELIGARD",
      "status": "COMPLETED",
      "last_update": "2014-06-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00379561",
      "title": "PSA-Activated PSA-PAH1 for Locally Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-10-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00428714",
      "title": "Phase 2 Trial of Enzastaurin in Prostate Cancer in Participants Who Have Had Hormonal and Chemotherapy",
      "status": "COMPLETED",
      "last_update": "2020-11-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00433797",
      "title": "Dietary Intervention With Phytochemicals and Polyunsaturated Fatty Acids in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2013-12-19",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00450008",
      "title": "Safety and Efficacy Study of GM-CSF, Thalidomide Plus Docetaxel in Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2016-03-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00450463",
      "title": "Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-11-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00499408",
      "title": "Vitamin D and Soy Supplements in Treating Patients With Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-11-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00514917",
      "title": "A Study of Androgen Deprivation With Leuprolide, +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Participants With a Rising Prostate Specific Antigen (PSA)",
      "status": "TERMINATED",
      "last_update": "2013-11-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00544830",
      "title": "Hormone Therapy and Intensity-Modulated Radiation Therapy in Treating Patients With Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00551525",
      "title": "Samarium Sm 153 Lexidronam Pentasodium and 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Rising Prostate-Specific Antigen Levels After Radical Prostatectomy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-07-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00554086",
      "title": "Open Label,Phase II Trial of MAB Dose Escalation OF Bicalutamide For Biochemical Failure In Prostate Cancer Patients.",
      "status": "COMPLETED",
      "last_update": "2011-05-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00558363",
      "title": "ARTS - AVODART After Radical Therapy For Prostate Cancer Study",
      "status": "COMPLETED",
      "last_update": "2012-03-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00567580",
      "title": "Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2025-05-09",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00629330",
      "title": "Dissemination of Prostate Cancer Screening to PCP's in African American Communities",
      "status": "TERMINATED",
      "last_update": "2015-10-14",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00630188",
      "title": "Shared Decision Making for Prostate Cancer Screening: a Practice-Based Randomized Controlled Trial",
      "status": "COMPLETED",
      "last_update": "2008-03-06",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00637208",
      "title": "Sclerotherapy of Internal Spermatic Veins in Patients With Varicocele and Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2008-03-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00658697",
      "title": "Docetaxel, Bevacizumab and Androgen Deprivation Therapy After Definitive Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-05-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00667862",
      "title": "Efficacy and Safety Study of Panobinostat in Participants With Metastatic Hormone Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00676780",
      "title": "Green Tea Extract and Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-08-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00681148",
      "title": "Botulinum Toxin Injection With Prostate Brachytherapy",
      "status": "WITHDRAWN",
      "last_update": "2013-11-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00685633",
      "title": "Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2013-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00705835",
      "title": "Vaccine Therapy of Prostate Cancer Patients With Recombinant Soluble Prostate-Specific Membrane Antigen (Rs-PSMA) Plus the Immunological Adjuvant Alhydrogel",
      "status": "COMPLETED",
      "last_update": "2012-01-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00715078",
      "title": "To Evaluate Sipuleucel-T Manufactured With Different Concentrations of (PA2024) Antigen",
      "status": "COMPLETED",
      "last_update": "2017-05-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00726596",
      "title": "Hydroxychloroquine in Treating Patients With Rising PSA Levels After Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00731848",
      "title": "Open-label Extension Study of the Effects of Pomegranate Extract on Rising PSA After Primary Therapy for Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2012-03-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00732043",
      "title": "Extension to Study of Effects of Pomegranate Extract on Rising PSA Levels After Primary Therapy for Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2012-03-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00738673",
      "title": "Degarelix as Second-Line Hormonal Treatment After Prostate-specific Antigen (PSA)-Failure in GnRH Agonist Treated Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-01-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00761124",
      "title": "Informed Decision-Making Regarding Prostate Specific Antigen (PSA) Screening in 50-70 Year Old Latino Men",
      "status": "COMPLETED",
      "last_update": "2026-08-31",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00774436",
      "title": "Study of Focal Cryoablation in Low-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-07-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00817739",
      "title": "Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c",
      "status": "COMPLETED",
      "last_update": "2015-07-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00831792",
      "title": "TKI258 in Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00853710",
      "title": "Test Semiquantitative Prostate Specific Antigen (PSA)",
      "status": "COMPLETED",
      "last_update": "2025-11-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00859729",
      "title": "Dose Finding Study of a DNA Vaccine Delivered With Intradermal Electroporation in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-03-17",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00860652",
      "title": "Radiotherapy - Adjuvant Versus Early Salvage",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2022-11-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00861471",
      "title": "Docetaxel (Taxotere) and Imatinib Mesylate (Gleevec) in Hormone Refractory Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2016-06-30",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00872157",
      "title": "BMTP-11 in Patients With Castrate-Resistant Prostate Cancer With Bone Mets",
      "status": "COMPLETED",
      "last_update": "2015-10-23",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00878436",
      "title": "Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration",
      "status": "COMPLETED",
      "last_update": "2018-02-07",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00901342",
      "title": "Open Label Study of Sipuleucel-T in Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-05-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00911079",
      "title": "Pilot Study of a Catheter-based Ultrasound Hyperthermia System",
      "status": "TERMINATED",
      "last_update": "2021-07-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00916123",
      "title": "Docetaxel/Prednisone Plus Fractionated 177Lu- J591 Antibody for Metastatic, Castrate-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00928434",
      "title": "A Study of Degarelix in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-12-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00955058",
      "title": "Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients",
      "status": "UNKNOWN",
      "last_update": "2009-09-03",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01036594",
      "title": "Ketoconazole and Dexamethasone in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-06-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01046916",
      "title": "Safety and Efficacy Study of TAK-700 in Patients With Nonmetastatic Castration-resistant Prostate Cancer and a Rising Prostate-specific Antigen",
      "status": "COMPLETED",
      "last_update": "2016-04-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01054079",
      "title": "Cinacalcet Hydrochloride in Treating Men With Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-07-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01095848",
      "title": "A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-12-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01118741",
      "title": "Study of Recurrent Prostate Cancer With Rising Prostate Specific Antigen (PSA)",
      "status": "COMPLETED",
      "last_update": "2018-06-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01145508",
      "title": "Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2017-09-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01162135",
      "title": "Digoxin for Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01168323",
      "title": "Spaced Education to Optimize Prostate Cancer Screening",
      "status": "COMPLETED",
      "last_update": "2010-08-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01171898",
      "title": "Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2026-06-05",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01194960",
      "title": "TroVax\u00ae In Subjects With Hormone Refractory Prostate Cancer (HRPC)",
      "status": "TERMINATED",
      "last_update": "2020-10-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01220817",
      "title": "Safety and Efficacy of POMx Capsules in Men With Recurrent Prostate Cancer: An 18-Month Study",
      "status": "COMPLETED",
      "last_update": "2012-04-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01220973",
      "title": "Atorvastatin Calcium and Celecoxib in Treating Patients With Rising PSA Levels After Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-06-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01241656",
      "title": "Decision Support Interventions (DESI) for Prostate Cancer Screening - Study 1",
      "status": "COMPLETED",
      "last_update": "2013-06-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01296672",
      "title": "3 Month Finasteride Challenge Test Can Significantly Improve the Performance of Screening for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-10-06",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01302041",
      "title": "A Study to Test if Enzalutamide is Effective and Safe in Prostate Cancer Patients Who Have Never Had Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2018-10-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01304485",
      "title": "PET Imaging Characteristics of C11-Acetate in Patients With Recurrent Prostate Carcinoma",
      "status": "COMPLETED",
      "last_update": "2019-03-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01309672",
      "title": "S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2025-02-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01314118",
      "title": "IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen",
      "status": "COMPLETED",
      "last_update": "2026-02-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01317199",
      "title": "Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-04-02",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01337518",
      "title": "A Phase 1a/1b Study to Evaluate the Safety of EZN-4176, in Adult Patients With Castration-Resistant Prostate Cancer",
      "status": "SUSPENDED",
      "last_update": "2012-12-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01377389",
      "title": "Ipilimumab + Androgen Depravation Therapy in Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01415375",
      "title": "Prostate Cancer Education in African American Men",
      "status": "COMPLETED",
      "last_update": "2015-04-17",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01415960",
      "title": "Efficacy and Safety of Leuprolide Acetate 22.5 mg Depot in Treatment of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-03-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01417182",
      "title": "Biodistribution and Pharmacokinetic Study of 18F-DCFBC Prostate Specific Membrane Antigen Based PET in Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-01-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01420861",
      "title": "GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-10-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01434004",
      "title": "Eating, Activity, and Stress Education",
      "status": "COMPLETED",
      "last_update": "2019-04-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01477749",
      "title": "Sipuleucel-T Manufacturing Demonstration Study",
      "status": "COMPLETED",
      "last_update": "2015-12-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01487863",
      "title": "Concurrent vs. Sequential Sipuleucel-T & Abiraterone Treatment in Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01516801",
      "title": "A Pragmatic Trial of the Effect of a Mailed Patient Flyer About Prostate Specific Antigen (PSA) Testing Prior to an Annual Exam",
      "status": "COMPLETED",
      "last_update": "2012-01-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01521949",
      "title": "Study of Acai Juice in Asymptomatic or Minimally Symptomatic Prostate Cancer Patients With Rising PSA",
      "status": "COMPLETED",
      "last_update": "2018-06-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01538316",
      "title": "Prostate Cancer Prevention Trial With Quercetin and Genistein",
      "status": "UNKNOWN",
      "last_update": "2012-05-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01558427",
      "title": "Non-systemic Treatment for Patients With Low-volume Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-09-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01561482",
      "title": "Study of Metformin With Simvastatin for Men With Prostate Carcinoma",
      "status": "WITHDRAWN",
      "last_update": "2015-07-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01576029",
      "title": "Continued Treatment With Docetaxel Versus Switch to Cabazitaxel After Minor Prostate Specific Antigen Response to Docetaxel in Patients With Castration-Resistant Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-12-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01681433",
      "title": "OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone",
      "status": "TERMINATED",
      "last_update": "2022-07-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01681823",
      "title": "Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA",
      "status": "COMPLETED",
      "last_update": "2020-01-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01682941",
      "title": "Soy Isoflavones in Treating Patients With Recurrent Prostate Cancer or Rising Prostate-Specific Antigen",
      "status": "COMPLETED",
      "last_update": "2023-11-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01685983",
      "title": "A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01696877",
      "title": "A Neoadjuvant Study of Androgen Ablation Combined With Cyclophosphamide and GVAX Vaccine for Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-28",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01739062",
      "title": "The ProCaRis Study: Prostate Cancer Risk Assessment in General Practice",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2023-12-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01812902",
      "title": "Prospective Study Comparing Extended With Limited Pelvic Lymphadenectomy in Intermediate and High Risk Prostate Cancer Patients Undergoing Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2018-05-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01827813",
      "title": "Comparison Of Effectiveness of Transrectal Ultrasonography-Guided Saturation Biopsy And 10-12 Core Biopsy In Repeated Prostate Biopsies",
      "status": "COMPLETED",
      "last_update": "2013-04-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01867333",
      "title": "Enzalutamide With or Without Vaccine Therapy for Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-09-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01875250",
      "title": "Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02044172",
      "title": "Prostate Testing for Cancer and Treatment",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2022-11-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02048150",
      "title": "Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02058680",
      "title": "Phase 1A/1B Study of PSA/IL-2/GM-CSF Vaccine for Recurrent Prostate Cancer in Hormone Naive and Hormone Independent Patients",
      "status": "UNKNOWN",
      "last_update": "2018-09-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02091531",
      "title": "Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients",
      "status": "COMPLETED",
      "last_update": "2019-11-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02153918",
      "title": "Vaccine Plus Booster Shots in Men With Prostate Cancer Undergoing Treatment With Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2018-10-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02176161",
      "title": "Metformin Prostate Cancer Adjuvant Trial",
      "status": "COMPLETED",
      "last_update": "2022-10-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02190279",
      "title": "18F-DCFBC PET/CT in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-04-23",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02202447",
      "title": "Phase 1 of EC1169 In Patients With Recurrent MCRPC",
      "status": "COMPLETED",
      "last_update": "2019-02-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02203695",
      "title": "Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2025-10-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02217566",
      "title": "Study of Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC), Chemo-Naive, Who Received a Prior Diethylstilbestrol Therapy",
      "status": "COMPLETED",
      "last_update": "2020-01-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02252978",
      "title": "Ciprofloxacin Compared to Placebo in Diagnosing Prostate Cancer in Patients Undergoing Prostate Biopsy",
      "status": "WITHDRAWN",
      "last_update": "2018-07-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02282137",
      "title": "68Ga-PSMA PET-CT Scan for Diagnosis and Management of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2020-08-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02294461",
      "title": "An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer Participants",
      "status": "COMPLETED",
      "last_update": "2025-10-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02319239",
      "title": "Prostate Cancer Stereotactic Radiotherapy",
      "status": "COMPLETED",
      "last_update": "2020-10-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02326805",
      "title": "PROSTVAC (PSA-TRICOM) in Preventing Disease Progression in Patients With Localized Prostate Cancer Undergoing Active Surveillance",
      "status": "COMPLETED",
      "last_update": "2023-07-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02381015",
      "title": "Clinical Validity and Utility of Genomic-targeted Chemoprevention of PCa: Aim 4a",
      "status": "COMPLETED",
      "last_update": "2019-11-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02410577",
      "title": "89Zr-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients With Glioblastoma Multiforme",
      "status": "COMPLETED",
      "last_update": "2019-03-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02415621",
      "title": "Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-04",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02420652",
      "title": "Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy",
      "status": "TERMINATED",
      "last_update": "2023-02-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02485964",
      "title": "A Pilot Study to Assess the Immunogenicity of Candidate PSA Peptides for a Prostate Cancer Vaccine",
      "status": "COMPLETED",
      "last_update": "2021-10-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02497638",
      "title": "LIpitor and biGuanide to Androgen Delay Trial",
      "status": "WITHDRAWN",
      "last_update": "2021-04-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02506114",
      "title": "Neoadjuvant PROSTVAC-VF With or Without Ipilimumab for Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2021-11-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02649439",
      "title": "Prostvac in Patients With Biochemically Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-11-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02649855",
      "title": "Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-04-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02678351",
      "title": "68Ga-PSMA-11 PET/MRI in Finding Tumors in Patients With Intermediate or High-Risk Prostate Cancer Undergoing Surgery",
      "status": "COMPLETED",
      "last_update": "2022-03-04",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02680041",
      "title": "18F Fluciclovine (FACBC) PET/CT in Patients With Rising PSA After Initial Prostate Cancer Treatment",
      "status": "COMPLETED",
      "last_update": "2019-01-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02710422",
      "title": "Miami Membrane for Potency (MMEP) Trial",
      "status": "TERMINATED",
      "last_update": "2019-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02796898",
      "title": "Study of the Efficacy, Safety, and Pharmacokinetics of SM88 in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-07-22",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02799303",
      "title": "MRI Versus PSA in Prostate Cancer Screening",
      "status": "UNKNOWN",
      "last_update": "2019-10-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02852122",
      "title": "The Role of C-11 Choline PET in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-01-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02918968",
      "title": "Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-12-09",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02919111",
      "title": "Gallium-68 PSMA-11 PET in Intermediate to High-risk Preprostatectomy Patients",
      "status": "COMPLETED",
      "last_update": "2020-12-10",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02933255",
      "title": "PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-05-31",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03042312",
      "title": "Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy",
      "status": "TERMINATED",
      "last_update": "2021-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03087903",
      "title": "A Study of Grape Seed Extract in Asymptomatic Non-Metastatic Prostate Cancer Patients With Rising PSA",
      "status": "COMPLETED",
      "last_update": "2025-03-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03187990",
      "title": "Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men With Elevated PSA",
      "status": "COMPLETED",
      "last_update": "2021-09-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03207113",
      "title": "Adoption, Acceptability, and Effectiveness of a Mobile Health App for Personalised Prostate Cancer Survivorship Care.",
      "status": "UNKNOWN",
      "last_update": "2017-10-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03315871",
      "title": "Combination Immunotherapy in Biochemically Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-06-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03362359",
      "title": "Ga-68-PSMA-11 in High-risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-07-27",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03368547",
      "title": "68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery",
      "status": "COMPLETED",
      "last_update": "2023-04-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03392428",
      "title": "A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03423303",
      "title": "A Randomized Trial of Early Detection of Clinically Significant Prostate Cancer (ProScreen)",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2025-04-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03431753",
      "title": "Early and Accurate Detection of Prostate Cancer in General Practice",
      "status": "UNKNOWN",
      "last_update": "2021-05-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03443609",
      "title": "Study of 68Ga-HBED-PSMA PET/CT and Conventional Imaging in Occult Biological Relapse Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-21",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03449719",
      "title": "Phase II Randomized Trial of Radiation Therapy in Oligometastatic mCRPC Prostate Cancer (ARTO)",
      "status": "UNKNOWN",
      "last_update": "2018-02-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03453528",
      "title": "Investigation of PSMA PET/CT as an Imaging Biomarker in Solid Tumors",
      "status": "COMPLETED",
      "last_update": "2025-01-08",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03471650",
      "title": "Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03477591",
      "title": "Evaluating the Impact of Evidence-based Information About PSA Testing on Prostate Cancer Screening Decisions",
      "status": "COMPLETED",
      "last_update": "2023-10-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03515577",
      "title": "Gallium Ga 68-labeled PSMA-11 PET/CT and Fluciclovine F18 PET/CT in Imaging Participants With Recurrent Prostate Cancer After Surgery",
      "status": "COMPLETED",
      "last_update": "2020-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03517969",
      "title": "M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03531827",
      "title": "Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment",
      "status": "TERMINATED",
      "last_update": "2022-07-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03532217",
      "title": "Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-08-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03533946",
      "title": "Rucaparib in Nonmetastatic prOstAte With BRCAness",
      "status": "TERMINATED",
      "last_update": "2024-03-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03535675",
      "title": "Muscadine Plus (MPX) In Men With Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-05-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03537391",
      "title": "Novel Imaging in Staging of Primary Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-05-04",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03568188",
      "title": "Efficacy Evaluation of Focused HIFU (High Intensity Focused Ultrasound) Therapy in Patients With Localized Intermediate Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03579654",
      "title": "Study of Proscavax Vaccine in Patients With Localized Prostate Cancer vs Active Surveillance",
      "status": "UNKNOWN",
      "last_update": "2019-03-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03600350",
      "title": "pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03604757",
      "title": "68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Prostate Cancer Imaging According to Various Metastatic Risks",
      "status": "COMPLETED",
      "last_update": "2026-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03632980",
      "title": "Dynamic Focusing Evaluation for Prostate Cancer Treatment",
      "status": "UNKNOWN",
      "last_update": "2018-08-16",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03690141",
      "title": "An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03739684",
      "title": "Study of 18F-DCFPyL PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-06-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03762759",
      "title": "Fluciclovine F18 or Ga68-PSMA PET/CT to Enhance Prostate Cancer Outcomes",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03796767",
      "title": "Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-07-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03803475",
      "title": "Gallium-68 PSMA-11 PET Imaging in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2021-08-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03823001",
      "title": "Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2022-05-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03824275",
      "title": "18F-DCFPyL Positron Emission Tomography (PET)/Computed Tomography (CT) in Men With Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2022-05-11",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03828838",
      "title": "Lutetium-177-PSMA-617 in Low Volume Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-11-14",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03869216",
      "title": "Fostering Shared Decision-making About Prostate Cancer Screening Among Clinicians and African American Men",
      "status": "COMPLETED",
      "last_update": "2025-12-29",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03976843",
      "title": "Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03979573",
      "title": "Prospective Evaluation of Mp-MRI, MR-guided Biopsy, and Molecular Markers for Active Surveillance of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2019-06-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03995888",
      "title": "Assessing Radio-hybrid Prostate Specific Membrane Antigen (rhPSMA-7.3) (18F) in Healthy Volunteers and Subjects With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04019964",
      "title": "Nivolumab in Biochemically Recurrent dMMR Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04053062",
      "title": "LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer",
      "status": "SUSPENDED",
      "last_update": "2024-01-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04063566",
      "title": "ReIMAGINE Prostate Cancer Screening",
      "status": "COMPLETED",
      "last_update": "2021-10-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04090528",
      "title": "pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04108208",
      "title": "A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant Prostate Cancer (NM-CRPC)",
      "status": "COMPLETED",
      "last_update": "2026-07-30",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04186819",
      "title": "Imaging Study to Investigate the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) in Newly Diagnosed Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2025-02-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04227275",
      "title": "A Study of CART-PSMA-TGF\u03b2RDN in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04248621",
      "title": "Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2021-07-29",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04249947",
      "title": "P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)",
      "status": "TERMINATED",
      "last_update": "2025-02-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04282824",
      "title": "Impact of Monosodium Glutamate on 68GA-PSMA-11, PET Imaging Biodistribution in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-12-02",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04317625",
      "title": "Screening for Prostate Cancer Among Those Prostate-specific Antigen Value Between 2.5 and 4.0 ng/mL",
      "status": "UNKNOWN",
      "last_update": "2020-03-23",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04322045",
      "title": "Combined Prostate-specific Antigen, Multi-parametric MRI and Targeted Prostate Biopsy for Prostate Cancer Screening",
      "status": "UNKNOWN",
      "last_update": "2020-03-26",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04429451",
      "title": "PSMA-specific CAR-T Cell Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04530552",
      "title": "Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland",
      "status": "COMPLETED",
      "last_update": "2026-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04716725",
      "title": "68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04727736",
      "title": "18F-DCFPyL Positron Emission Tomography (PET) in Intermediate or High Risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-02-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04745871",
      "title": "Diagnostic Performance of PSMA PET/CT for Pre-operative Lymph Node Assessment in Intermediate and High-risk Non-metastasic Prostate Cancer (PREOP-PSMA ).",
      "status": "TERMINATED",
      "last_update": "2026-06-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04773821",
      "title": "Performance of Prostate MRI and Following Biopsy to Detect Prostate Cancer Recurrence After Focal Therapy",
      "status": "UNKNOWN",
      "last_update": "2022-03-29",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04776889",
      "title": "The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2021-03-02",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04782713",
      "title": "Smart Prostate Specific Antigen (PSA) Screening Study",
      "status": "COMPLETED",
      "last_update": "2026-01-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04790968",
      "title": "Combined PSMA PET/MRI for Detection of Lymph Node Metastases in High-risk Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2024-11-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04808427",
      "title": "Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer",
      "status": "SUSPENDED",
      "last_update": "2026-08-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04931979",
      "title": "SRT in Combination With Pembrolizumab in Patients With Recurrent Prostate Cancer After Radical Prostatectomy",
      "status": "UNKNOWN",
      "last_update": "2023-03-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04936334",
      "title": "The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05009186",
      "title": "Changing of Prostate Specific Antigen Value in Patients With Covid-19",
      "status": "UNKNOWN",
      "last_update": "2021-08-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05025527",
      "title": "Biparametric MRI in Prostate Cancer Screening: a Noninferior Randomized Controlled Study",
      "status": "UNKNOWN",
      "last_update": "2022-10-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05114746",
      "title": "Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan",
      "status": "COMPLETED",
      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05160597",
      "title": "Image-Guided (68Ga-PSMA-11 PET/CT) Prostate Biopsy for the Diagnosis of Prostate Cancer in Men With Prior Negative/Inconclusive Biopsy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-12",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05219500",
      "title": "Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST).",
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      "last_update": "2026-04-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05232578",
      "title": "Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2022-08-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05331638",
      "title": "Prostate Cancer Genius App Education and Home-based PSA Screening for African American Men",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05489991",
      "title": "A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2023-08-18",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05500846",
      "title": "Targeted Cryoablation of Prostate Cancer Lesions: An Investigator-initiated Trial",
      "status": "UNKNOWN",
      "last_update": "2024-06-21",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05522257",
      "title": "PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell Carcinomas",
      "status": "COMPLETED",
      "last_update": "2024-12-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05603351",
      "title": "Prostate Cancer Screening With Abbreviated MRI Protocol",
      "status": "UNKNOWN",
      "last_update": "2022-11-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05617040",
      "title": "Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-11-10",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05680675",
      "title": "Dual-Tracer Theranostic PET",
      "status": "COMPLETED",
      "last_update": "2025-02-06",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05700370",
      "title": "MyProstateScore Equivalency With and Without DRE",
      "status": "UNKNOWN",
      "last_update": "2023-01-26",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05733351",
      "title": "Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-09-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05794906",
      "title": "A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo Given With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05836623",
      "title": "A Phase I Study to Assess PSMA+ and PSMA- Tumour Lesions",
      "status": "UNKNOWN",
      "last_update": "2024-02-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05900973",
      "title": "A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05902247",
      "title": "Actium-225-Prostate Specific Membrane Antigen Imaging & Therapy",
      "status": "UNKNOWN",
      "last_update": "2023-06-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05961514",
      "title": "the Beijing Randomized Study Of Prostate Cancer Screening",
      "status": "UNKNOWN",
      "last_update": "2023-11-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06101927",
      "title": "Molecular Imaging of Prostate-Specific Membrane Antigen Using Labeled Technetium-99m BQ0413",
      "status": "COMPLETED",
      "last_update": "2026-06-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06129851",
      "title": "Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2023-11-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06237491",
      "title": "The Safety and Dosimetry Study of 177Lu-LNC1003 Injection",
      "status": "UNKNOWN",
      "last_update": "2024-07-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06238661",
      "title": "Prostate Cancer Screening: a Pilot Study",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2026-03-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06384222",
      "title": "Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone",
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      "last_update": "2026-09-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06441994",
      "title": "Clinical Trial of Targeted Alpha Therapy Using [At-211]PSMA-5 for Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06549036",
      "title": "Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06765902",
      "title": "Immunotherapy Before and After Surgery",
      "status": "WITHDRAWN",
      "last_update": "2026-05-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06849544",
      "title": "Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection",
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      "last_update": "2026-08-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06966089",
      "title": "ExosomeDx in MRI-negative Men With High PSA",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-05-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06982222",
      "title": "Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones",
      "status": "WITHDRAWN",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07069465",
      "title": "Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging",
      "status": "COMPLETED",
      "last_update": "2025-07-16",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07101354",
      "title": "Research on PSMA-Targeted Intraoperative Fluorescent Imaging Agents",
      "status": "COMPLETED",
      "last_update": "2025-08-03",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07387510",
      "title": "PSMA-Targeted Intraoperative Fluorescent Imaging Agents (DGPR1008): Validation Across Different Time Windows",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-02-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07489729",
      "title": "Hypo Fractionated Versus Conventional IMRT in Unfavorable Intermediate- and High-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-03-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07593079",
      "title": "Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer",
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      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07644754",
      "title": "Patients With Metastasized Prostate Cancer Whose Prostate-specific Antigen-level (PSA) Remains >0,2 ng/ml After Six Months of Dual Antihormonal Therapy Will Receive Radiotherapy to the Prostate and Radiotherapy to Refractory Metastases",
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      "last_update": "2026-06-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07645326",
      "title": "RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)",
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      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07650240",
      "title": "Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial",
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      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07686380",
      "title": "IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07733440",
      "title": "PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-29",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07733908",
      "title": "Effectiveness of Posluma PET Scan for Post-Treatment Monitoring of Prostate Cancer",
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      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07747493",
      "title": "68Ga-PSMA-11 PET/MRI for Selecting Men With Prostate Cancer for Focal Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-05",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07766486",
      "title": "Prospective Study on the Role of Radical Prostatectomy in Oligo-metastatic Hormone-sensitive Prostate Cancer in Patients on Androgen Deprivation Therapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-14",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07813637",
      "title": "Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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    ],
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       "nct": "NCT04053062",
       "title": "LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer",
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       "last_update": "2024-01-05",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT04227275",
       "title": "A Study of CART-PSMA-TGF\u03b2RDN in Patients With Metastatic Castration Resistant Prostate Cancer",
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       "last_update": "2023-08-21",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT04249947",
       "title": "P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)",
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       "last_update": "2025-02-17",
       "phase": "PHASE1",
       "study_type": "INTERVENTIONAL"
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      {
       "nct": "NCT04429451",
       "title": "PSMA-specific CAR-T Cell Therapy",
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       "last_update": "2026-08-26",
       "phase": "PHASE1/PHASE2",
       "study_type": "INTERVENTIONAL"
      },
      {
       "nct": "NCT05489991",
       "title": "A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
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       "last_update": "2023-08-18",
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       "study_type": "INTERVENTIONAL"
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     ]
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     "KLK3"
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      "nct": "NCT05489211",
      "title": "Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)",
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      "last_update": "2026-08-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06851663",
      "title": "Trop2-targeted immunoPET Imaging of Solid Tumors",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07179783",
      "title": "Sacituzumab Tirumotecan in Combination With Tagitanlimab in the Treatment of Aggressive Variant Prostate Cancer (AVPC) and Neuroendocrine Prostate Cancer (NEPC)",
      "status": "RECRUITING",
      "last_update": "2025-09-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01631552",
      "title": "Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer",
      "status": "COMPLETED",
      "last_update": "2021-08-12",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03725761",
      "title": "Sacituzumab Govitecan in Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Second Generation AR-Directed Therapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04381832",
      "title": "Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-07-22",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07639086",
      "title": "Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ],
    "cell_therapy": {
     "n": 0,
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      "title": "Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer",
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     {
      "nct": "NCT04221542",
      "title": "Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT04633252",
      "title": "A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer",
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      "title": "A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer",
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      "title": "Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer",
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      "title": "Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer",
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      "title": "Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.",
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      "phase": "PHASE2",
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     {
      "nct": "NCT05818683",
      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
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      "nct": "NCT06059118",
      "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer",
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     {
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      "title": "Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer",
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      "title": "A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer",
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      "last_update": "2025-09-26",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06350825",
      "title": "Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients",
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      "last_update": "2024-04-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06369610",
      "title": "Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer",
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      "last_update": "2025-11-14",
      "phase": "PHASE2",
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     {
      "nct": "NCT06378866",
      "title": "Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial",
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      "last_update": "2026-07-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06496581",
      "title": "Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)",
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      "last_update": "2024-12-20",
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     {
      "nct": "NCT06592924",
      "title": "Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
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      "last_update": "2026-07-14",
      "phase": "PHASE3",
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     {
      "nct": "NCT06832774",
      "title": "Exploration of Treatment Effect of Novel Hormone Therapy Combined With Local Treatment Based on PSMA PET/CT Evaluation in mHSCP Patients",
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      "last_update": "2026-03-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06844383",
      "title": "A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide",
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      "last_update": "2026-08-21",
      "phase": "PHASE2",
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     {
      "nct": "NCT06863272",
      "title": "A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)",
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      "last_update": "2026-09-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06952803",
      "title": "A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation",
      "status": "RECRUITING",
      "last_update": "2026-08-21",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07001709",
      "title": "Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate Cancer (the ENABLE Study)",
      "status": "RECRUITING",
      "last_update": "2025-06-03",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07230106",
      "title": "A Study of SHR3680, HS-20093 and SHR2554 in Subjects With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-03-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07237269",
      "title": "Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer",
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      "last_update": "2026-08-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07287150",
      "title": "A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07483658",
      "title": "Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.",
      "status": "RECRUITING",
      "last_update": "2026-07-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07611110",
      "title": "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)",
      "status": "RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07717268",
      "title": "Fractionated Stereotactic Radiotherapy Plus Second-generation Antiandrogen for Oligometastatic Castration-resistant Prostate Cancer Patients.",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07751133",
      "title": "Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00473746",
      "title": "Abiraterone Acetate Dose-Escalation Study in Hormone Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-04-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00485303",
      "title": "An Efficacy and Safety Study of Abiraterone Acetate and Prednisone in Participants With Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy",
      "status": "COMPLETED",
      "last_update": "2013-07-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00544440",
      "title": "An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma",
      "status": "COMPLETED",
      "last_update": "2014-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00600535",
      "title": "A Pharmacokinetics Study to Assess Abiraterone Acetate Capsule and Tablet Formulations in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-04-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00924469",
      "title": "A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone Acetate in Male Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-04-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01023061",
      "title": "Abiraterone Prednisone and Hormonal Therapy Before and During Radiation Therapy in Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-06-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01088529",
      "title": "Neo-adjuvant Abiraterone + Luteinizing Hormone-Releasing Hormone (LHRH) Versus LHRH in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01309672",
      "title": "S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2025-02-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01314118",
      "title": "IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen",
      "status": "COMPLETED",
      "last_update": "2026-02-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01400555",
      "title": "A Safety Study of Abiraterone Acetate Administered in Combination With Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
      "status": "COMPLETED",
      "last_update": "2018-03-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01424930",
      "title": "A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-07-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01511536",
      "title": "Cabazitaxel and Abiraterone Acetate in Patients With Metastatic Castrate-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-07-28",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01517802",
      "title": "A Study That Provides Long-term Safety Follow-up and Examines Long-term Exposure to Abiraterone Acetate",
      "status": "COMPLETED",
      "last_update": "2022-05-10",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01543776",
      "title": "Food Effect Study of Abiraterone Acetate for Treatment of Patients With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-07-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01553188",
      "title": "AMG 386 and Abiraterone for Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01574937",
      "title": "XL-184+Abiraterone in Post-Chemo CRPC",
      "status": "COMPLETED",
      "last_update": "2021-08-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01576172",
      "title": "Abiraterone Acetate and Prednisone With or Without Veliparib in Treating Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-11-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01591122",
      "title": "Study of Abiraterone Acetate Plus Prednisone in Patients With Chemo-naive Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-21",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01605227",
      "title": "Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100",
      "status": "COMPLETED",
      "last_update": "2018-03-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01681433",
      "title": "OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone",
      "status": "TERMINATED",
      "last_update": "2022-07-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01685125",
      "title": "Abiraterone Acetate and Prednisone With or Without Dasatinib in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2017-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01685268",
      "title": "A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate",
      "status": "COMPLETED",
      "last_update": "2024-08-02",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01685983",
      "title": "A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01688492",
      "title": "Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-na\u00efve Patients With Progressive Metastatic Castration-resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-12",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01695135",
      "title": "A Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Docetaxel-Based Chemotherapy",
      "status": "COMPLETED",
      "last_update": "2019-07-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01715285",
      "title": "A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)",
      "status": "COMPLETED",
      "last_update": "2025-02-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01717053",
      "title": "Abiraterone, Radiotherapy and Short-Term Androgen Deprivation in Unfavorable Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-10-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01735396",
      "title": "Abiraterone Acetate Trial in African American Prostate Cancer Patients",
      "status": "TERMINATED",
      "last_update": "2017-05-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01741753",
      "title": "BKM120+Abiraterone Acetate for Metastatic CRPC",
      "status": "TERMINATED",
      "last_update": "2019-02-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01780220",
      "title": "Radiotherapy Plus Hormone Therapy in Biochemically-relapsing Prostate Cancer Patients Following Surgery",
      "status": "COMPLETED",
      "last_update": "2022-05-19",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01786265",
      "title": "Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01828476",
      "title": "Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating Patients With Progressive Metastatic Castrate Refractory Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2017-05-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01848067",
      "title": "Alisertib, Abiraterone Acetate and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-04",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01884285",
      "title": "AZD8186 First Time In Patient Ascending Dose Study",
      "status": "COMPLETED",
      "last_update": "2020-05-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01946165",
      "title": "Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2019-12-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01994590",
      "title": "Dovitinib (TKI258) and Abiraterone Acetate in Metastatic Castrate-Resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2019-03-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01995513",
      "title": "Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2023-09-18",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02001571",
      "title": "A Study to Assess the Effect of Abiraterone Acetate in Male Participants With Mild or Moderate Hepatic Impairment Compared to Matched Control Participants With Normal Hepatic Function",
      "status": "COMPLETED",
      "last_update": "2013-12-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02034552",
      "title": "A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2019-07-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02043678",
      "title": "Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms",
      "status": "COMPLETED",
      "last_update": "2025-02-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02091531",
      "title": "Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients",
      "status": "COMPLETED",
      "last_update": "2019-11-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02097303",
      "title": "Open Label Phase Two Trial of Radium Ra 223 Dichloride With Concurrent Administration of Abiraterone Acetate Plus Prednisone in Symptomatic Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Bone Metastasis",
      "status": "COMPLETED",
      "last_update": "2018-02-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02121600",
      "title": "18F-FCH PET/MRI to Assess Tumor Response in Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2019-05-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02123758",
      "title": "A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02130947",
      "title": "Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer Receiving Abiraterone or Enzalutamide",
      "status": "WITHDRAWN",
      "last_update": "2016-02-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02159690",
      "title": "A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and Degarelix in Men With Localized Prostate Cancer Pre-prostatectomy",
      "status": "WITHDRAWN",
      "last_update": "2015-01-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02202447",
      "title": "Phase 1 of EC1169 In Patients With Recurrent MCRPC",
      "status": "COMPLETED",
      "last_update": "2019-02-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02204072",
      "title": "BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2025-07-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02218606",
      "title": "Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-12-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02257736",
      "title": "An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02268175",
      "title": "Enzalutamide/Leuprolide +/- Abiraterone/Pred in Prostate",
      "status": "COMPLETED",
      "last_update": "2022-04-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
      "status": "COMPLETED",
      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02405858",
      "title": "A Study of Abiraterone Acetate in Metastatic Castration-Resistant Prostate Cancer Participants Who Responded Poorly to the First-line Combined Androgen Blockade Therapy",
      "status": "COMPLETED",
      "last_update": "2025-02-03",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02415621",
      "title": "Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-04",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02543255",
      "title": "Anti-Androgens and Cabazitaxel in Defining Complete Response in Prostatectomy (ACDC Trial)",
      "status": "COMPLETED",
      "last_update": "2024-01-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02656615",
      "title": "Abiraterone-Rechallenge Study for CRPC Patients",
      "status": "TERMINATED",
      "last_update": "2017-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02703623",
      "title": "Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02730975",
      "title": "Pharmacokinetic Food-effect Study of Abiraterone Acetate (AA) in Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-01-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02740985",
      "title": "A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies",
      "status": "COMPLETED",
      "last_update": "2023-05-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02758132",
      "title": "Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases",
      "status": "TERMINATED",
      "last_update": "2019-11-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02789878",
      "title": "Neoadjuvant Androgen Deprivation Therapy Plus Abiraterone With or Without Apalutamide for High-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-09-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02849990",
      "title": "A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy",
      "status": "COMPLETED",
      "last_update": "2022-01-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02887976",
      "title": "Extension of SoluMatrix TM Abiraterone Acetate in Patients Who Completed Study Number CHL-AA-201",
      "status": "COMPLETED",
      "last_update": "2020-07-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02903160",
      "title": "Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2024-02-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02924766",
      "title": "A Safety and Pharmacokinetics Study of Niraparib Plus an Androgen Receptor-Targeted Therapy in Men With Metastatic Castration-Resistant Prostate Cancer (BEDIVERE)",
      "status": "COMPLETED",
      "last_update": "2020-07-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02975934",
      "title": "A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency",
      "status": "COMPLETED",
      "last_update": "2025-07-25",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02987543",
      "title": "Study of Olaparib (Lynparza\u2122) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)",
      "status": "COMPLETED",
      "last_update": "2023-10-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02991911",
      "title": "A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03002220",
      "title": "Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 Status",
      "status": "COMPLETED",
      "last_update": "2024-12-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03012321",
      "title": "Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03016741",
      "title": "Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-24",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03043807",
      "title": "A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2023-02-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03072238",
      "title": "Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Metastatic Castrate-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-06-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03093272",
      "title": "A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2020-04-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03141671",
      "title": "Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)",
      "status": "UNKNOWN",
      "last_update": "2024-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03148795",
      "title": "A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-04-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03170960",
      "title": "Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03279250",
      "title": "Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-08-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03348670",
      "title": "Pharmacogenomics IND Commercial SNP Clinical Study - Abiraterone and Single Nucleotide Polymorphisms",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-10",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03418324",
      "title": "Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy",
      "status": "COMPLETED",
      "last_update": "2020-12-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03449719",
      "title": "Phase II Randomized Trial of Radiation Therapy in Oligometastatic mCRPC Prostate Cancer (ARTO)",
      "status": "UNKNOWN",
      "last_update": "2018-02-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03551782",
      "title": "A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-02-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03556904",
      "title": "FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE)",
      "status": "COMPLETED",
      "last_update": "2026-01-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03569280",
      "title": "Evaluation of Safety and Efficacy of KPG-121 Plus Enzalutamide, Abiraterone or Apalutamide in CRPC Patients",
      "status": "COMPLETED",
      "last_update": "2023-07-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03587285",
      "title": "A Pilot Study of Hormonal Therapy Combined With Central Memory T Cells (Tcm) for Patients With Advanced Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2019-08-01",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03649841",
      "title": "Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-10-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03690141",
      "title": "An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03811652",
      "title": "A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors",
      "status": "COMPLETED",
      "last_update": "2019-12-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03860987",
      "title": "Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03939689",
      "title": "I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).",
      "status": "COMPLETED",
      "last_update": "2025-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03999515",
      "title": "Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-09-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04015622",
      "title": "PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04115007",
      "title": "Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-06-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04139772",
      "title": "Docetaxel or Hormone Therapy as Second Line Treatment in Patients With Asymptomatic or Oligosymptomatic Metastatic Castration-resistent Prostate Cancer (mCRPC) Progressing After Abiraterone or Enzalutamide.",
      "status": "UNKNOWN",
      "last_update": "2023-03-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04267887",
      "title": "Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04296578",
      "title": "Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant Prostate Cancer Progressing on Abiraterone",
      "status": "WITHDRAWN",
      "last_update": "2021-08-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04356430",
      "title": "Neoadjuvant Therapy of Abiraterone Plus ADT for High Risk Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-12-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04458311",
      "title": "Abiraterone Acetate in Combination With Tildrakizumab",
      "status": "TERMINATED",
      "last_update": "2024-04-25",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04478279",
      "title": "A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04556617",
      "title": "PLX2853 in Combination With Abiraterone Acetate and Prednisone and in Combination With Olaparib in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2025-04-08",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04577833",
      "title": "A Study of Comparative Formulations of Niraparib and Abiraterone Acetate (AA) in Men With Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04597125",
      "title": "RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-06",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04603833",
      "title": "A Study of SHR3680 in Combination With Docetaxel in the Treatment of mCRPC",
      "status": "UNKNOWN",
      "last_update": "2021-02-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04628988",
      "title": "A Study of CC-90011 and Comparators in Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-09-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04647526",
      "title": "Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04677855",
      "title": "Study of PCUR-101 in Combination With ADT in Patients With mCRPC",
      "status": "TERMINATED",
      "last_update": "2024-04-10",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04726332",
      "title": "Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101)",
      "status": "TERMINATED",
      "last_update": "2024-05-14",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04736108",
      "title": "Neoadjuvant Therapy of Abiraterone Plus ADT for Intraductal Carcinoma of the Prostate",
      "status": "UNKNOWN",
      "last_update": "2021-02-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04748042",
      "title": "Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towards Castration Sensitive Oligometastatic Prostate Cancer (FAALCON)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04839055",
      "title": "The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC",
      "status": "UNKNOWN",
      "last_update": "2021-04-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04879589",
      "title": "Phase 1 Study of ATRS-2002 in Healthy Male Adults",
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      "nct": "NCT04887506",
      "title": "TAVT-45 (Abiraterone Acetate) Granules in Patients With Prostate Cancer",
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      "nct": "NCT04926155",
      "title": "The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer",
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      "nct": "NCT04992026",
      "title": "The Efficacy and Safety of Prostatectomy for Castration-Naive Oligometastatic Prostate Cancer",
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      "phase": "PHASE2",
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     {
      "nct": "NCT05022849",
      "title": "A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants",
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      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05114746",
      "title": "Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan",
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      "last_update": "2026-05-08",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05156450",
      "title": "TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2021-12-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05212857",
      "title": "Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer",
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      "last_update": "2022-03-16",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05223582",
      "title": "Fluzoparib and Abiraterone in the preSurgery Treatment of Prostate Cancer: FAST Trial",
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      "last_update": "2023-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05245435",
      "title": "Diagnostic and Prognostic Accuracy of FDHT-PET and Liquid Biopsies in Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2023-03-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05457257",
      "title": "Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations",
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      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05549778",
      "title": "Polaprezinc Treatment for Enzalutamide- or Abiraterone-resistant CRPC",
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      "last_update": "2023-07-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05574712",
      "title": "A Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate Cancer",
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      "last_update": "2024-03-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05588609",
      "title": "Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers",
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      "last_update": "2026-04-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05627752",
      "title": "Docetaxel Alone or in Combination With Enzalutamide for mCRPC Previously Treated With Abiraterone at mHSPC Stage",
      "status": "UNKNOWN",
      "last_update": "2024-02-28",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05707468",
      "title": "Neoadjuvant Radiohormonal Therapy for Oligometastatic Prostate Cancer",
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      "last_update": "2024-02-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05733351",
      "title": "Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer",
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      "last_update": "2025-09-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05771896",
      "title": "Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC",
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      "last_update": "2023-09-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06212583",
      "title": "High-Risk Metachronous Oligometastatic Prostate Cancer Trial",
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      "last_update": "2026-05-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06329830",
      "title": "177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2024-09-19",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06384222",
      "title": "Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone",
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      "last_update": "2026-09-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06421935",
      "title": "M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)",
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      "last_update": "2026-09-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06500247",
      "title": "Darxicilib Combined With Abiraterone Acetate Tablets (II) for the Treatment of Advanced Metastatic Castration-resistant Prostate Cancer.",
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      "last_update": "2024-07-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06505278",
      "title": "The Impact of Medication Timing Adjustment on the Effect of Novel Hormonal Therapy",
      "status": "UNKNOWN",
      "last_update": "2024-08-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06551324",
      "title": "A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06764485",
      "title": "A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer",
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      "last_update": "2026-09-08",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07172126",
      "title": "Clinical Trial to Evaluate the Tolerance of TQB3201 Tablets",
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      "last_update": "2025-09-15",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07268794",
      "title": "CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer",
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      "last_update": "2025-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07553988",
      "title": "A Comparative Dose-finding Study of RS-113 in Patients With Metastatic Castration-resistant Prostate Cancer",
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      "last_update": "2026-04-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07620574",
      "title": "Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study",
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      "last_update": "2026-08-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07641855",
      "title": "A Study of BL-B01D1 Combination Therapy in Patients With Metastatic Castration-resistant Prostate Cancer",
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      "last_update": "2026-07-23",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07645326",
      "title": "RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)",
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      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07650240",
      "title": "Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial",
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      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07730580",
      "title": "Study of XNW5004 Tablets in Advanced Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07802704",
      "title": "A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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      "nct": "NCT03903835",
      "title": "ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer",
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     {
      "nct": "NCT04423211",
      "title": "Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging",
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      "phase": "PHASE3",
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     {
      "nct": "NCT04729114",
      "title": "A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04787744",
      "title": "Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer",
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      "last_update": "2026-04-08",
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     {
      "nct": "NCT04812366",
      "title": "Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer",
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      "last_update": "2026-08-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04946370",
      "title": "Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer",
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      "last_update": "2026-04-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04947254",
      "title": "Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer",
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      "last_update": "2026-06-23",
      "phase": "PHASE2",
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      "nct": "NCT05191680",
      "title": "TherApeutics in Early ProState Cancer (TAPS02)",
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      "last_update": "2025-06-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05209243",
      "title": "START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC",
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      "last_update": "2023-05-19",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05406999",
      "title": "Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer",
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      "last_update": "2022-08-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05413421",
      "title": "Study of ORIC-944 in Patients With Metastatic Prostate Cancer",
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      "last_update": "2026-07-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05422911",
      "title": "Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.",
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      "last_update": "2026-06-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05534646",
      "title": "Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer",
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      "last_update": "2026-02-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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      "nct": "NCT05647564",
      "title": "PET/CT Characterization of Treatment Resistance",
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      "last_update": "2026-09-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05649943",
      "title": "Multimodal Approach in Patients With mHSPC. Randomized Trial of APA+ADT vs APA-ADT and Local Treatment",
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      "last_update": "2025-09-03",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05818683",
      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
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      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05974774",
      "title": "Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors",
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      "last_update": "2025-09-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06067269",
      "title": "Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial",
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      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06095089",
      "title": "A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer",
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      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06274047",
      "title": "PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.",
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      "last_update": "2026-07-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06320067",
      "title": "A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-09-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06350825",
      "title": "Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients",
      "status": "RECRUITING",
      "last_update": "2024-04-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06378866",
      "title": "Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial",
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      "last_update": "2026-07-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06496581",
      "title": "Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)",
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      "last_update": "2024-12-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06585007",
      "title": "Metastasis-directed Therapy in Oligoprogressive Castration-refractory Prostate Cancer",
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      "last_update": "2024-09-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06592924",
      "title": "Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
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      "last_update": "2026-07-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06758882",
      "title": "Surgical Treatment With or Without Apalutamide in Subjects With High Risk Prostate Cancer Who Are Candidates for Radical Prostatectomy and Staged as Oligometastatic With PSMA-PET",
      "status": "RECRUITING",
      "last_update": "2025-01-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06832774",
      "title": "Exploration of Treatment Effect of Novel Hormone Therapy Combined With Local Treatment Based on PSMA PET/CT Evaluation in mHSCP Patients",
      "status": "RECRUITING",
      "last_update": "2026-03-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06931340",
      "title": "Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial",
      "status": "RECRUITING",
      "last_update": "2026-09-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06992232",
      "title": "Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC",
      "status": "RECRUITING",
      "last_update": "2025-05-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07002320",
      "title": "Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07182279",
      "title": "Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-03-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07260435",
      "title": "Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-12-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07333066",
      "title": "Phase III Randomized International Open Label Clinical Trial of Treatment Intensification With Docetaxel Plus Apalutamide in Patients With Metastatic Hormone-sensitive Prostate Cancer Who Did Not Achieve a Deep PSA Response After Initial Treatment With Apalutamide: REINFORCE Trial.",
      "status": "RECRUITING",
      "last_update": "2026-06-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07611110",
      "title": "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)",
      "status": "RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07745361",
      "title": "Study of Oral MRT-2359 With Apalutamide in Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07751133",
      "title": "Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01171898",
      "title": "Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2026-06-05",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01790126",
      "title": "The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01792687",
      "title": "Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of Ascending Doses of ARN 509 in Combination With Abiraterone Acetate",
      "status": "COMPLETED",
      "last_update": "2025-03-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01946204",
      "title": "A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
      "status": "COMPLETED",
      "last_update": "2022-06-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02106507",
      "title": "ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone Acetate",
      "status": "COMPLETED",
      "last_update": "2023-05-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02123758",
      "title": "A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02257736",
      "title": "An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02489318",
      "title": "A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02531516",
      "title": "An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02578797",
      "title": "A JNJ-56021927 (ARN-509; Apalutamide) QT/QTc Study",
      "status": "COMPLETED",
      "last_update": "2023-11-09",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02703623",
      "title": "Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02711956",
      "title": "A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-11-30",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02721979",
      "title": "Apalutamide in Treating Patients With Prostate Cancer Who Are in Active Surveillance",
      "status": "TERMINATED",
      "last_update": "2023-02-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02770391",
      "title": "Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02772588",
      "title": "AASUR in High Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-04-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02789878",
      "title": "Neoadjuvant Androgen Deprivation Therapy Plus Abiraterone With or Without Apalutamide for High-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-09-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02811809",
      "title": "Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2020-02-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02849990",
      "title": "A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy",
      "status": "COMPLETED",
      "last_update": "2022-01-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02867020",
      "title": "Study of Abiraterone Acetate Plus ADT Versus APALUTAMIDE Versus Abiraterone and APALUTAMIDE in Patients With Advanced Prostate Cancer With Non-castrate Testosterone Levels",
      "status": "COMPLETED",
      "last_update": "2021-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02903368",
      "title": "Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2025-06-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02906605",
      "title": "A Study of the Clinical Activity and Safety of JNJ-64041809, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Apalutamide Versus Apalutamide in Subjects With Metastatic Castration-resistant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2016-11-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02913196",
      "title": "Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPC",
      "status": "COMPLETED",
      "last_update": "2026-04-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02924766",
      "title": "A Safety and Pharmacokinetics Study of Niraparib Plus an Androgen Receptor-Targeted Therapy in Men With Metastatic Castration-Resistant Prostate Cancer (BEDIVERE)",
      "status": "COMPLETED",
      "last_update": "2020-07-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02949284",
      "title": "Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate, Gonadotropin-Releasing Hormone Analog, and Prednisone in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03009981",
      "title": "A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-12-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03080116",
      "title": "Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy",
      "status": "UNKNOWN",
      "last_update": "2024-07-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03088124",
      "title": "Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-03-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03093272",
      "title": "A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2020-04-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03098836",
      "title": "Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03124433",
      "title": "Neoadjuvant Apalutamide (ARN509) and Radical Prostatectomy in Treatment of Intermediate to High Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-03-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03141671",
      "title": "Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)",
      "status": "UNKNOWN",
      "last_update": "2024-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03170960",
      "title": "Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03173859",
      "title": "Efficacy of Rotations Between Abiraterone Acetate and Apalutamide in mCRPC Patients",
      "status": "WITHDRAWN",
      "last_update": "2020-11-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03279250",
      "title": "Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-08-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03298087",
      "title": "Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-08-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03311555",
      "title": "A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR)",
      "status": "COMPLETED",
      "last_update": "2024-03-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03360721",
      "title": "Apalutamide, Abiraterone Acetate, and Prednisone in Treating Participants With Metastatic Castration Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-03-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03365297",
      "title": "Therapeutics in Active Prostate Cancer Surveillance",
      "status": "COMPLETED",
      "last_update": "2019-11-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03371719",
      "title": "Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03412396",
      "title": "Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03436654",
      "title": "Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03488810",
      "title": "Apalutamide With Radiotherapy and Androgen Deprivation Therapy in Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2020-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03503344",
      "title": "Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-01-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03523442",
      "title": "A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03551782",
      "title": "A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-02-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03569280",
      "title": "Evaluation of Safety and Efficacy of KPG-121 Plus Enzalutamide, Abiraterone or Apalutamide in CRPC Patients",
      "status": "COMPLETED",
      "last_update": "2023-07-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03690141",
      "title": "An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03767244",
      "title": "A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03777982",
      "title": "Conventional Androgen Deprivation Therapy (ADT) With or Without Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT",
      "status": "TERMINATED",
      "last_update": "2024-09-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03821792",
      "title": "Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03840200",
      "title": "A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2023-10-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03899077",
      "title": "Radiotherapy Combined With a LHRH (Ant)Agonist Versus Apalutamide in Patients With Biochemical Recurrence After RP",
      "status": "UNKNOWN",
      "last_update": "2024-02-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03902951",
      "title": "Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04104893",
      "title": "A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04108208",
      "title": "A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant Prostate Cancer (NM-CRPC)",
      "status": "COMPLETED",
      "last_update": "2026-07-30",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04115007",
      "title": "Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-06-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04134260",
      "title": "Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04181203",
      "title": "Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-07-30",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04267887",
      "title": "Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04295447",
      "title": "Adjuvant Apalutamide in Subjects With High-risk Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2024-06-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04409288",
      "title": "Patient Preference of Apalutamide Versus Enzalutamide in Patients With Recurrent or Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-01-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04421222",
      "title": "Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-02-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04478279",
      "title": "A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04495179",
      "title": "A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.",
      "status": "COMPLETED",
      "last_update": "2023-08-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04513717",
      "title": "Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04523207",
      "title": "A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases",
      "status": "COMPLETED",
      "last_update": "2026-04-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04530552",
      "title": "Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland",
      "status": "COMPLETED",
      "last_update": "2026-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04557059",
      "title": "A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04585932",
      "title": "Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART Study",
      "status": "WITHDRAWN",
      "last_update": "2021-01-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04601441",
      "title": "Study to Evaluate ctDNA of mCSPC Patients Receiving Apalutamide in Japan",
      "status": "UNKNOWN",
      "last_update": "2020-12-08",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04662580",
      "title": "ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer",
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      "last_update": "2026-08-28",
      "phase": "PHASE1",
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     {
      "nct": "NCT04666129",
      "title": "Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2025-08-17",
      "phase": "PHASE1",
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     },
     {
      "nct": "NCT04926181",
      "title": "Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer",
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      "last_update": "2025-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04997252",
      "title": "An Evaluation of the Efficacy and Safety of Apalutamide as Neoadjuvant Endocrine Therapy in High-Risk and Oligometastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-03-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05192694",
      "title": "Evaluation of Fapi-pet in Prostate Cancer.",
      "status": "UNKNOWN",
      "last_update": "2022-03-11",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05212857",
      "title": "Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-03-16",
      "phase": "PHASE2",
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     {
      "nct": "NCT05241860",
      "title": "Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)",
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      "last_update": "2026-08-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05295927",
      "title": "A Study of EPI-7386 in Combination With Abiraterone Acetate Plus Prednisone, or Apalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC)",
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      "last_update": "2025-02-03",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05367440",
      "title": "Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05683964",
      "title": "Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-13",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05717582",
      "title": "Maximal Cytoreductive Therapies on Post-treatment Metastases in Pts With mHSPC During Apalutamide Plus ADT Treatment",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2023-02-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05717660",
      "title": "APalutamiAPalutamide and stEReotactic Body Radiation Therapy for Metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-02-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05740488",
      "title": "Efficacy and Safety of Apalutamide in Combination With 89Sr as Neoadjuvant Therapy in Prostate Cancer With \u226410 Bone Metastases",
      "status": "UNKNOWN",
      "last_update": "2024-03-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05751941",
      "title": "Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05771896",
      "title": "Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC",
      "status": "WITHDRAWN",
      "last_update": "2023-09-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05778097",
      "title": "Adjutant Apalutamide Plus ADT in Post-RP Patients With High Risk of Recurrence (ARES Study)",
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      "last_update": "2023-03-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05849298",
      "title": "A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05884398",
      "title": "A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05960578",
      "title": "Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06505278",
      "title": "The Impact of Medication Timing Adjustment on the Effect of Novel Hormonal Therapy",
      "status": "UNKNOWN",
      "last_update": "2024-08-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06734130",
      "title": "Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06894511",
      "title": "An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07268794",
      "title": "CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07389174",
      "title": "Safety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-02-05",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07645326",
      "title": "RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07783282",
      "title": "A Study to Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed in Men With Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07795177",
      "title": "A Prospective Study Based on Spatial Multi-omics to Predict the Efficacy of ADT Combined With Second-generation Novel Hormonal Agents in Metastatic Hormone-sensitive Prostate Cancer.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ]
   },
   "APC-100": {
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     {
      "nct": "NCT01436214",
      "title": "Dose-Escalation and Safety Study of APC-100 for the Treatment of Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2015-07-16",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ]
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     {
      "nct": "NCT01162395",
      "title": "Open Label Prostate Cancer Study",
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      "last_update": "2016-01-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01351688",
      "title": "An Open Label Prostate Cancer Study in Japanese Patients",
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    ]
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      "nct": "NCT03541928",
      "title": "Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery",
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      "last_update": "2021-04-06",
      "phase": "PHASE2",
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     {
      "nct": "NCT03678025",
      "title": "Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer",
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      "last_update": "2025-09-11",
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     {
      "nct": "NCT04734730",
      "title": "Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer",
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      "last_update": "2026-01-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04787744",
      "title": "Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer",
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      "last_update": "2026-04-08",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05019846",
      "title": "SRT Versus SRT+ADT in Prostate Cancer",
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      "last_update": "2023-04-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05781217",
      "title": "Short Versus Long-term Androgen Deprivation Therapy With Salvage Radiotherapy in Prostate Cancer. URONCOR 0624",
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      "last_update": "2023-11-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06650579",
      "title": "REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial",
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      "last_update": "2026-02-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07182279",
      "title": "Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer",
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      "last_update": "2026-03-09",
      "phase": "PHASE1/PHASE2",
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     {
      "nct": "NCT07393867",
      "title": "Androgen-responsive POSLUMA-guided Intra-prostatic Boost",
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      "last_update": "2026-05-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07455903",
      "title": "Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT",
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      "last_update": "2026-08-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00002633",
      "title": "Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-04-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00002651",
      "title": "SWOG-9346, Hormone Therapy in Treating Men With Stage IV Prostate Cancer",
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      "last_update": "2017-04-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00002855",
      "title": "Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer",
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      "last_update": "2018-10-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00002874",
      "title": "Radiation Therapy With or Without Bicalutamide for Recurrent pT3N0 Prostate Cancer After Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2022-06-15",
      "phase": "PHASE3",
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     {
      "nct": "NCT00003026",
      "title": "Hormone Therapy in Treating Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-07-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00003517",
      "title": "Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2013-07-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00003645",
      "title": "Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence",
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      "last_update": "2020-04-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00003653",
      "title": "Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer",
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      "last_update": "2021-06-23",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00004054",
      "title": "Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer",
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      "last_update": "2020-10-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00004124",
      "title": "S9921, Hormone Therapy With or Without Mitoxantrone and Prednisone in Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-12-30",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00005044",
      "title": "Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-15",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00006359",
      "title": "Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-07-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00014586",
      "title": "Bicalutamide Compared With Observation Followed by Bicalutamide Plus Either Goserelin or Orchiectomy in Treating Patients With Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2012-09-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00021450",
      "title": "Radiation Therapy With or Without Bicalutamide and Goserelin in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-09-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00023829",
      "title": "Adjuvant Radiation Therapy Plus Hormone Therapy Compared With Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-10-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00026377",
      "title": "SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-09-05",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00028769",
      "title": "S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00030654",
      "title": "Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-10-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00031889",
      "title": "Exemestane With or Without Bicalutamide in Treating Patients With Stage IV Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00055731",
      "title": "Hormone Therapy With or Without Docetaxel And Estramustine in Treating Patients With Prostate Cancer That is Locally Advanced or At High Risk of Relapse",
      "status": "COMPLETED",
      "last_update": "2023-01-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00067015",
      "title": "Radiation Therapy With or Without Bicalutamide and Goserelin in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-12-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00075192",
      "title": "CP-675,206 With Neoadjuvant Hormone Therapy in Patients With High Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-06-06",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00086736",
      "title": "Neoadjuvant Eflornithine and Bicalutamide Compared With Eflornithine Alone, Bicalutamide Alone, and No Neoadjuvant Therapy in Treating Patients With Localized Prostate Cancer Undergoing Brachytherapy or Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2013-11-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00099086",
      "title": "Docetaxel, Radiation Therapy, and Hormone Therapy in Treating Patients With Locally Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-01-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00108732",
      "title": "A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-06-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00165399",
      "title": "Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment",
      "status": "COMPLETED",
      "last_update": "2018-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00170157",
      "title": "Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00175396",
      "title": "Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy",
      "status": "UNKNOWN",
      "last_update": "2014-03-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00188708",
      "title": "Effect of Casodex on Tumour Hypoxia - Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-03-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00223145",
      "title": "Study on the Role of Hormonal Treatment for Two Dosage Levels of Prostate Radiation Therapy Versus Prostate Radiation Therapy Alone",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-01-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00223171",
      "title": "Duration of Androgen Blockade Combined With Pelvic Irradiation in Prostate Cancers",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-01-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00233610",
      "title": "Two Different Regimens of Nolvadex in Preventing Gynecomastia Induced by Casodex 150 mg in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2011-01-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00243646",
      "title": "Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A Prospective Randomized Trial",
      "status": "TERMINATED",
      "last_update": "2016-04-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00244920",
      "title": "Hormone Therapy With or Without Squalamine Lactate in Treating Patients Who Are Undergoing a Radical Prostatectomy for Locally Advanced Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2012-05-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00255268",
      "title": "CMAB vs IMAB in Metastatic Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2007-08-28",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00283803",
      "title": "Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00293696",
      "title": "Casodex/Zoladex Biomarkers in Localised Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2007-05-08",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00298155",
      "title": "Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-08-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00303784",
      "title": "Prostate Adenocarcinoma TransCutaneous Hormones",
      "status": "UNKNOWN",
      "last_update": "2020-11-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00309985",
      "title": "Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-12-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00319787",
      "title": "Combination Casodex\u00ae and Iressa\u2122 in Locally Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2011-01-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00328614",
      "title": "Samarium-153 With Neoadjuvant Hormonal and Radiation Therapy for Locally Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00348998",
      "title": "Bevacizumab, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2013-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00349557",
      "title": "Bevacizumab With Hormonal and Radiotherapy for High-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00388804",
      "title": "External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2012-08-08",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00418080",
      "title": "Survival Outcomes and Tumor Molecular Profile Following Bicalutamide Neoadjuvant Therapy",
      "status": "COMPLETED",
      "last_update": "2007-10-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00421694",
      "title": "Positive Surgical Margins Rate and EGFR Family Members Expression in Prostate Cancer Treated With Bicalutamide",
      "status": "COMPLETED",
      "last_update": "2007-10-08",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00430235",
      "title": "A Study of BAY 43-9006 in Combination With Bicalutamide in Patients With Chemo-Na\u00efve Hormone Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2010-08-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00470834",
      "title": "Prostate Cancer Study In Men Who Have Failed First-Line Androgen Deprivation Therapy",
      "status": "COMPLETED",
      "last_update": "2017-02-27",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00482807",
      "title": "Radiation Therapy, Docetaxel, and Hormone Therapy in High-Risk Locally Advanced Metastasized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-11-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00486642",
      "title": "Pazopanib Hydrochloride With or Without Bicalutamide in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2017-05-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00512668",
      "title": "Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2013-01-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00514917",
      "title": "A Study of Androgen Deprivation With Leuprolide, +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Participants With a Rising Prostate Specific Antigen (PSA)",
      "status": "TERMINATED",
      "last_update": "2013-11-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00520052",
      "title": "Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2007-08-23",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00521781",
      "title": "Study of Abraxane Plus Hormonal Therapy as Initial Treatment of Unresectable or Metastatic Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2016-03-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00528866",
      "title": "Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2019-04-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00536653",
      "title": "Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2007-09-28",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00541047",
      "title": "RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery",
      "status": "COMPLETED",
      "last_update": "2023-11-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00544830",
      "title": "Hormone Therapy and Intensity-Modulated Radiation Therapy in Treating Patients With Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00551044",
      "title": "Bicalutamide Monotherapy Has Significant Quality of Life Benefits for Men With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2007-10-30",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00554086",
      "title": "Open Label,Phase II Trial of MAB Dose Escalation OF Bicalutamide For Biochemical Failure In Prostate Cancer Patients.",
      "status": "COMPLETED",
      "last_update": "2011-05-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00567580",
      "title": "Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2025-05-09",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00586898",
      "title": "Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle",
      "status": "COMPLETED",
      "last_update": "2016-03-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00589472",
      "title": "Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-10-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00590213",
      "title": "Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX",
      "status": "COMPLETED",
      "last_update": "2008-01-25",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00630344",
      "title": "RAD001 and Bicalutamide for Androgen Independent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00631527",
      "title": "Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-01-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00637871",
      "title": "Casodex - Nolvadex Combination",
      "status": "COMPLETED",
      "last_update": "2011-01-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00651326",
      "title": "Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-08-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00657904",
      "title": "Bicalutamide (Casodex\u2122) Versus Placebo in Patients With Early Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-06-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00658697",
      "title": "Docetaxel, Bevacizumab and Androgen Deprivation Therapy After Definitive Local Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-05-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00659438",
      "title": "Efficacy and Safety of Zactima\u2122 in Patients With Castration-refractory Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-12-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00666666",
      "title": "R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-12-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00669162",
      "title": "Postoperative Radiation Therapy, Hormonal Therapy and Concurrent Docetaxel for High Risk Pathologic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-07-24",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00672282",
      "title": "Casodex vs Placebo in Non-Metastatic Early Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2009-05-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00673205",
      "title": "(Bicalutamide) Casodex vs Placebo in Non-metastatic Early Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2010-12-10",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00684905",
      "title": "Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy",
      "status": "COMPLETED",
      "last_update": "2012-11-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00685633",
      "title": "Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2013-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00702923",
      "title": "CP-675,206 in Combination With Short Term Androgen Deprivation in Patients With Stage D0 Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2019-11-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00757692",
      "title": "Efficacy and Safety Study of Vandetanib (ZD 6474) in Combination With Bicalutamide Versus Bicalutamide Alone in Patients With Chemotherapy Naive Hormone Refractory Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2013-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00764166",
      "title": "A Prospective Randomized Phase III Study Comparing Hormonal Therapy +/-Docetaxel",
      "status": "UNKNOWN",
      "last_update": "2008-10-01",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00769795",
      "title": "Study of Effectiveness of IMC-A12 Antibody Combined With Hormone Therapy Prior to Surgery to Treat Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-03-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00771017",
      "title": "Androgen Ablation Therapy With or Without Vaccine Therapy in Treating Patients With Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2023-05-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00776594",
      "title": "Androgen Deprivation Therapy +/- Bevacizumab for PSA Recurrence of Prostate Cancer After Definitive Local Therapy",
      "status": "COMPLETED",
      "last_update": "2016-10-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00777959",
      "title": "Bicalutamide and Ridaforolimus in Men With Prostate Cancer (MK-8669-002)",
      "status": "COMPLETED",
      "last_update": "2015-08-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00814788",
      "title": "Bicalutamide With or Without Everolimus in Treating Patients With Recurrent or Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-01-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00831233",
      "title": "Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2013-11-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00833248",
      "title": "Neoadjuvant Study Investigating Degarelix in Patients Suffering From Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2012-10-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00841113",
      "title": "Abarelix Versus Goserelin Plus Bicalutamide in Patients With Advanced or Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2009-02-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00846976",
      "title": "Treatment Protocol to Monitor the Safety of a 200 mg Dose of Bicalutamide in Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-01-21",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00866554",
      "title": "Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for Brachytherapy",
      "status": "COMPLETED",
      "last_update": "2023-06-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00878436",
      "title": "Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration",
      "status": "COMPLETED",
      "last_update": "2018-02-07",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00884273",
      "title": "Investigation of the Effect of Degarelix in Terms of Prostate Volume Reduction in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2013-11-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00924807",
      "title": "Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2018-12-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00928434",
      "title": "A Study of Degarelix in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-12-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00936390",
      "title": "Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-03-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00943956",
      "title": "Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-05-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00959335",
      "title": "Relative Bioavailability Study of Bicalutamide 50 mg Tablet and Casodex Following a 50 mg Dose in Healthy Subjects Under Fasting Conditions",
      "status": "COMPLETED",
      "last_update": "2017-03-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00960310",
      "title": "Relative Bioavailability Study of Bicalutamide 50 mg Tablet and Casodex Following a 50 mg Dose in Healthy Subjects Under Fed Conditions",
      "status": "COMPLETED",
      "last_update": "2017-03-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01020305",
      "title": "Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2014-10-13",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01050842",
      "title": "Bicalutamide and Raloxifene in Treating Patients With Metastatic or Hormone-Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-03-23",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01120236",
      "title": "Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-02-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01200810",
      "title": "Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2017-12-02",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01250717",
      "title": "Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2014-02-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01251861",
      "title": "Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-06-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01288911",
      "title": "A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-12-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01313273",
      "title": "Study of Lanreotide in Non Metastatic Castration-resistant Prostate Cancer Patients",
      "status": "TERMINATED",
      "last_update": "2019-11-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01342367",
      "title": "Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-06-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01420250",
      "title": "Cabazitaxel With Radiation and Hormone Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01531205",
      "title": "Neoadjuvant Chemohormonal Therapy Followed by Salvage Surgery for High Risk PSA",
      "status": "TERMINATED",
      "last_update": "2014-11-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01546987",
      "title": "Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-03-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01642732",
      "title": "Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2017-05-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01658527",
      "title": "TAK-700 in Castration Resistant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2016-06-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01664923",
      "title": "Safety and Efficacy Study of Enzalutamide Versus Bicalutamide in Men With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-01-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01674270",
      "title": "Degarelix Neo-Adjuvant Radical Prostatectomy Trial",
      "status": "COMPLETED",
      "last_update": "2015-12-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01786265",
      "title": "Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01809691",
      "title": "S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-12-31",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02058706",
      "title": "LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-05-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02059213",
      "title": "A Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02064036",
      "title": "Stereotactic Boost and Long-Term Androgen Deprivation for Adenocarcinoma of the Prostate",
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      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02085252",
      "title": "A Study of the Effect of Enantone LP 11.25 mg (Leuprorelin) on the Histological Progression of Indolent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-06-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
      "status": "COMPLETED",
      "last_update": "2022-06-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02175212",
      "title": "Clinical Trials of Adjuvant Androgen Deprivation in Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-11-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02346253",
      "title": "High-Dose Brachytherapy in Treating Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-07-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02346578",
      "title": "Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.",
      "status": "COMPLETED",
      "last_update": "2021-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02382094",
      "title": "Clinical Trial to Study Quality of Life in Prostate Cancer Patients by Randomizing Anti-androgen Versus Total Androgen Blockage Prior to Curative Intended Radiation Therapy",
      "status": "COMPLETED",
      "last_update": "2015-03-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02454543",
      "title": "Impact of Radical Prostatectomy as Primary Treatment in Patients With Prostate Cancer With Limited Bone Metastases",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02458716",
      "title": "Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-04-08",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02487823",
      "title": "Dose Finding Study of BKM 120 in Combination With LH-RH Agonists and Bicalutamide in Men With Non Castrate Metastatic Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2017-11-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02531516",
      "title": "An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02582749",
      "title": "Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases",
      "status": "TERMINATED",
      "last_update": "2022-07-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02605226",
      "title": "Cryoablation Therapy or Radiotherapy Therapy for Stage III Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2017-06-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02614859",
      "title": "Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2022-03-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02615223",
      "title": "Endocrine Therapy With or Without Cryoablation for Stage IV Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2017-06-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02678520",
      "title": "Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients",
      "status": "WITHDRAWN",
      "last_update": "2016-07-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02716974",
      "title": "A Study of Definitive Therapy to Treat Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-08-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02742675",
      "title": "Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)",
      "status": "UNKNOWN",
      "last_update": "2020-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02799706",
      "title": "Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-22",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02911350",
      "title": "Safety Study of Combination of Hormone Therapy, Paclitaxel and Radiation Therapy to Treat Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-10-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02918968",
      "title": "Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-12-09",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03009981",
      "title": "A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer",
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      "last_update": "2025-12-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03043807",
      "title": "A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy",
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      "last_update": "2023-02-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03070886",
      "title": "Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery",
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      "last_update": "2026-06-25",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03119857",
      "title": "Early Rising PSA Endocrine Treatment Versus Chemo-endocrine Therapy- SPCG14",
      "status": "UNKNOWN",
      "last_update": "2021-08-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03141671",
      "title": "Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)",
      "status": "UNKNOWN",
      "last_update": "2024-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03147196",
      "title": "Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery",
      "status": "WITHDRAWN",
      "last_update": "2019-01-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03348670",
      "title": "Pharmacogenomics IND Commercial SNP Clinical Study - Abiraterone and Single Nucleotide Polymorphisms",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-06-10",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03358563",
      "title": "Pilot Trial of Chemohormonal Therapy Followed by Prostatectomy in High Risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-05-03",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03488810",
      "title": "Apalutamide With Radiotherapy and Androgen Deprivation Therapy in Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2020-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03520478",
      "title": "A Study of SHR3680 in Treating Patients With Hormone Sensitive Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2021-03-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03587285",
      "title": "A Pilot Study of Hormonal Therapy Combined With Central Memory T Cells (Tcm) for Patients With Advanced Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2019-08-01",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03809000",
      "title": "A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery",
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      "last_update": "2025-12-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03878524",
      "title": "Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial",
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      "last_update": "2024-03-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03971110",
      "title": "A Study of Neoadjuvant Hormone Therapy in Patient With Advanced Prostate Cancer Undergoing Radical Prostatectomy.",
      "status": "TERMINATED",
      "last_update": "2022-12-16",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04025372",
      "title": "INTREPId (INTermediate Risk Erection PreservatIon Trial)",
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      "last_update": "2025-12-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04049747",
      "title": "Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-03-24",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04220398",
      "title": "Neoadjuvant Chemo-hormonal Therapy Combined With Radical Prostatectomy for Locally Advanced Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2020-01-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04248621",
      "title": "Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2021-07-29",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04284761",
      "title": "A Study to Establish the Feasibility of Biolen for the Local Delivery of Bicalutamide in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-06-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04513717",
      "title": "Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04563936",
      "title": "Efficacy and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX\u00ae",
      "status": "COMPLETED",
      "last_update": "2021-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04622761",
      "title": "Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome",
      "status": "UNKNOWN",
      "last_update": "2021-01-05",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04943536",
      "title": "Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-27",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05050084",
      "title": "Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05100472",
      "title": "A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-11-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05140512",
      "title": "Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX\u00ae",
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      "last_update": "2023-05-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05555017",
      "title": "Tracer-Guided Surgery for Recurrent Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-10-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05628363",
      "title": "Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05700903",
      "title": "Contributions to Hypertension With Androgen Deprivation Therapy",
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      "last_update": "2026-09-02",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05746806",
      "title": "Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-31",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05983198",
      "title": "Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06528210",
      "title": "Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2025-09-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07593079",
      "title": "Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07783282",
      "title": "A Study to Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed in Men With Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-24",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     }
    ]
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   "CAPROMAB": {
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     {
      "nct": "NCT00562315",
      "title": "FACBC PET/CT for Recurrent Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00992745",
      "title": "A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer",
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      "last_update": "2011-10-12",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02349022",
      "title": "Comparison of PET With [89Zr]-Df-IAb2M and [111In]-Capromab Pendetide in the Detection of Prostate Cancer Pre-Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2020-02-13",
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      "study_type": "INTERVENTIONAL"
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    ]
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     {
      "nct": "NCT00003653",
      "title": "Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-06-23",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00005623",
      "title": "Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-03-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00196339",
      "title": "A Clinical Trial to Study DR-2031 for the Treatment of Hot Flashes in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2016-07-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00363285",
      "title": "Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2013-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00849082",
      "title": "Radiation Therapy With or Without Goserelin and Cyproterone in Treating Patients With Prostate Cancer",
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      "nct": "NCT00955058",
      "title": "Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients",
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      "nct": "NCT01011751",
      "title": "Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT01819285",
      "title": "Early Compared With Delayed Hormone Therapy in Treating Patients With Nonmetastatic Prostate Cancer",
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      "nct": "NCT00441571",
      "title": "Safety Study of a Radiolabeled Antibody (7E11) in Patients With Progressive Hormone Refractory Prostate Cancer",
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      "nct": "NCT03903835",
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      "title": "A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer",
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      "title": "Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
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      "title": "Working Out M0 Bipolar Androgen Therapy",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06625970",
      "title": "Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse",
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      "title": "Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer",
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      "title": "A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC",
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     {
      "nct": "NCT06844383",
      "title": "A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide",
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      "last_update": "2026-08-21",
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      "title": "Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC",
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      "phase": "PHASE2",
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     {
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      "title": "Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07103018",
      "title": "A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)",
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      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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      "nct": "NCT07140900",
      "title": "Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer",
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      "last_update": "2026-07-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07142551",
      "title": "Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response",
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      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07172685",
      "title": "Study on Triple Therapy Combined With HIFU for High-Tumor-Burden mHSPC",
      "status": "RECRUITING",
      "last_update": "2025-09-15",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07182279",
      "title": "Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer",
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      "last_update": "2026-03-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07190300",
      "title": "TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)",
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      "last_update": "2026-06-23",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07244341",
      "title": "A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)",
      "status": "RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07450599",
      "title": "A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer.",
      "status": "RECRUITING",
      "last_update": "2026-08-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07611110",
      "title": "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)",
      "status": "RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07617272",
      "title": "Prostate Androgen Response Investigation Using a Stratification BIOmarker; Predicting Prostate Cancer Downstaging by Neoadjuvant Darolutamide With PCAI ImmunoScore",
      "status": "RECRUITING",
      "last_update": "2026-06-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07723248",
      "title": "A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)",
      "status": "RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07751133",
      "title": "Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01317641",
      "title": "Safety and Pharmacokinetics Study of ODM-201 in Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-03-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01429064",
      "title": "Safety and Tolerability of ODM-201 in Castrate Resistant Prostate Cancer; Extension Study to Study 3104001",
      "status": "COMPLETED",
      "last_update": "2017-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01784757",
      "title": "Bioavailability Study of ODM-201 in Subjects With Metastatic Chemotherapy-naive Castration-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-03-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02200614",
      "title": "Efficacy and Safety Study of Darolutamide (ODM-201) in Men With High-risk Non-metastatic Castration-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-06-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02363855",
      "title": "Phase 1 Dose Escalation Study of BAY 1841788 in Japanese Metastatic Castration-resistant Prostate Cancer (mCRPC) Subjects",
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      "last_update": "2018-01-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02799602",
      "title": "Darolutamide in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-12-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02933801",
      "title": "ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents.",
      "status": "TERMINATED",
      "last_update": "2024-03-13",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02972060",
      "title": "ODM-201 vs Androgen Deprivation Therapy in Hormone na\u00efve Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-09-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03237416",
      "title": "Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers",
      "status": "COMPLETED",
      "last_update": "2018-11-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03314324",
      "title": "A Study of Patient Preference Between ODM-201 and Enzalutamide in Men With Metastatic Castrate-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-08-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03385655",
      "title": "Prostate Cancer Biomarker Enrichment and Treatment Selection",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03551782",
      "title": "A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-02-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03568656",
      "title": "Study to Evaluate CCS1477 in Advanced Tumours",
      "status": "COMPLETED",
      "last_update": "2025-08-08",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03724747",
      "title": "Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Antitumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate Alone and in Combination With Darolutamide, in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-11-08",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03878524",
      "title": "Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial",
      "status": "TERMINATED",
      "last_update": "2024-03-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04025372",
      "title": "INTREPId (INTermediate Risk Erection PreservatIon Trial)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04070209",
      "title": "Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04104893",
      "title": "A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04136353",
      "title": "Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04157088",
      "title": "Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)",
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      "last_update": "2023-08-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04176081",
      "title": "Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2024-01-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04237584",
      "title": "A Study Comparing ARB With Radium-223 vs ARB Therapy With Placebo and the Effect Upon Survival for mCRPC Patients",
      "status": "TERMINATED",
      "last_update": "2022-10-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04319783",
      "title": "Darolutamide + Consolidation Radiotherapy in Advanced Prostate Cancer Detected by PSMA",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04335682",
      "title": "Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2026-06-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04484818",
      "title": "Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04495179",
      "title": "A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.",
      "status": "COMPLETED",
      "last_update": "2023-08-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04558866",
      "title": "Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)",
      "status": "COMPLETED",
      "last_update": "2026-08-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04641078",
      "title": "Stereotactic Body Radiotherapy With or Without Darolutamide for OligoRecurrent Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2024-02-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04736199",
      "title": "Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-02-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04737109",
      "title": "Neoadjuvant Androgen Deprivation, Darolutamide, and Ipatasertib in Men With Localized, High Risk Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-11-13",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04925648",
      "title": "Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction",
      "status": "COMPLETED",
      "last_update": "2026-04-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05050084",
      "title": "Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05059236",
      "title": "A Study to Learn How Well Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works in Men With Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study.",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05171387",
      "title": "Darolutamide + Androgen Deprivation Therapy (ADT) in Chinese Men With High Risk, Nonmetastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-06-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05249712",
      "title": "Efficacy and Safety of Darolutamide Combined With ADT in High-risk/Very High-risk Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-01-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05367440",
      "title": "Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05526248",
      "title": "A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05617885",
      "title": "Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-06-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05676203",
      "title": "A Trial Comparing Docetaxel 75 mg/m2 (3w) Versus Docetaxel 50 mg/m2 (2w) in Combination With Darolutamide + ADT in mHSPC Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05683964",
      "title": "Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-13",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05771896",
      "title": "Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC",
      "status": "WITHDRAWN",
      "last_update": "2023-09-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05794906",
      "title": "A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo Given With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05826509",
      "title": "SUrGery With or Without dARolutamide in High-risk and/or Locally Advanced Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05849298",
      "title": "A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05900973",
      "title": "A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05938270",
      "title": "A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.",
      "status": "COMPLETED",
      "last_update": "2026-06-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05999968",
      "title": "Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment",
      "status": "TERMINATED",
      "last_update": "2026-06-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06029036",
      "title": "A Phase II Neoadjuvant Study of Darolutamide Plus ADT in Men With Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-12-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06120491",
      "title": "Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-29",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06463457",
      "title": "Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06627530",
      "title": "COACTION Trial - COmbination Androgen bloCkade in inTermediate to hIgh-risk prOstate caNcer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-11",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06660862",
      "title": "Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-01-08",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06734130",
      "title": "Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06894511",
      "title": "An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-05-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07268794",
      "title": "CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07282197",
      "title": "Darolutamide+ADT Post-RP w/o ePLND in hrPC: Briganti 2019",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07389174",
      "title": "Safety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-02-05",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07476677",
      "title": "Darolutamide \u00b1 ADT as Neoadjuvant Therapy in High-Risk/Very High-Risk Localized Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-03-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07516704",
      "title": "Safety and Efficacy of Docetaxel, Darolutamide, and Homoharringtonine Combined With Androgen Deprivation Therapy in Neoadjuvant Treatment of High-Risk Prostate Cancer: A Multicenter Prospective, Single-Arm Clinical Study",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-04-08",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07591467",
      "title": "Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07645326",
      "title": "RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07649421",
      "title": "PSMA PET/CT-Guided SBRT Plus Darolutamide in mHSPC",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07677566",
      "title": "177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized Prostate Cancer: a Prospective, Single-arm, Multi-center Clinical Trial",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-01",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07711002",
      "title": "Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA \u2265 0.2 ng/mL (EvoPAR-PR05)",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07717099",
      "title": "Radium-223 for High-Volume Metastatic Hormone Sensitive Prostate Cancer",
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      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07730151",
      "title": "Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07795177",
      "title": "A Prospective Study Based on Spatial Multi-omics to Predict the Efficacy of ADT Combined With Second-generation Novel Hormonal Agents in Metastatic Hormone-sensitive Prostate Cancer.",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-08-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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      "nct": "NCT03753243",
      "title": "Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer",
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      "last_update": "2022-04-20",
      "phase": "PHASE2",
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     {
      "nct": "NCT04104776",
      "title": "A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas",
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      "phase": "PHASE1/PHASE2",
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     {
      "nct": "NCT04221542",
      "title": "Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-08-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04363164",
      "title": "Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression",
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      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04729114",
      "title": "A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer",
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      "last_update": "2026-02-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04946370",
      "title": "Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer",
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      "last_update": "2026-04-21",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04986423",
      "title": "ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05393791",
      "title": "Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC",
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      "last_update": "2024-11-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05422911",
      "title": "Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.",
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      "last_update": "2026-06-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05743621",
      "title": "Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-11-21",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05818683",
      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05974774",
      "title": "Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors",
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      "last_update": "2025-09-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06059118",
      "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-01-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT06096870",
      "title": "Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy",
      "status": "RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06126731",
      "title": "Combination Study of Antibiotics With Enzalutamide (PROMIZE)",
      "status": "RECRUITING",
      "last_update": "2025-11-24",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06136624",
      "title": "Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)",
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      "last_update": "2026-09-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06257693",
      "title": "Enzalutamide Implants (Enolen) in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06320067",
      "title": "A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2025-09-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06350825",
      "title": "Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients",
      "status": "RECRUITING",
      "last_update": "2024-04-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06378866",
      "title": "Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial",
      "status": "RECRUITING",
      "last_update": "2026-07-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06496581",
      "title": "Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)",
      "status": "RECRUITING",
      "last_update": "2024-12-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06499870",
      "title": "Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial",
      "status": "RECRUITING",
      "last_update": "2026-06-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06592924",
      "title": "Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
      "status": "RECRUITING",
      "last_update": "2026-07-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06655259",
      "title": "Combination of TURP and Standard Systemic Therapy for MPCa",
      "status": "RECRUITING",
      "last_update": "2024-10-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06844383",
      "title": "A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide",
      "status": "RECRUITING",
      "last_update": "2026-08-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06863272",
      "title": "A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)",
      "status": "RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06922318",
      "title": "The COSMYC Trial (COmbined Suppression of MYC)",
      "status": "RECRUITING",
      "last_update": "2026-06-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07182279",
      "title": "Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-03-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07230106",
      "title": "A Study of SHR3680, HS-20093 and SHR2554 in Subjects With Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-03-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07241416",
      "title": "A Phase III Clinical Study of Rezvilutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-05-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07287150",
      "title": "A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07611110",
      "title": "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)",
      "status": "RECRUITING",
      "last_update": "2026-08-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07717268",
      "title": "Fractionated Stereotactic Radiotherapy Plus Second-generation Antiandrogen for Oligometastatic Castration-resistant Prostate Cancer Patients.",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07751133",
      "title": "Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00510718",
      "title": "A Phase 1 Study of MDV3100 in Patients With Castration-Resistant (Hormone-Refractory) Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-10-03",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01091103",
      "title": "Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2018-10-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01534052",
      "title": "A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100",
      "status": "COMPLETED",
      "last_update": "2024-12-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01547299",
      "title": "Study of Enzalutamide (Formerly MDV3100) as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-10-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01565928",
      "title": "Safety and Tolerability Study of MDV3100 in Combination With Docetaxel in Men With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-04-22",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01605227",
      "title": "Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100",
      "status": "COMPLETED",
      "last_update": "2018-03-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01663415",
      "title": "A Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Na\u00efve, Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2012-09-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01875250",
      "title": "Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01885949",
      "title": "Tivozanib + Enzalutamide in Adv Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2026-05-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01911728",
      "title": "Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates",
      "status": "COMPLETED",
      "last_update": "2017-06-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01927627",
      "title": "Enzalutamide in Patients With High-risk Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01946165",
      "title": "Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2019-12-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01977651",
      "title": "A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2024-12-06",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01990196",
      "title": "Neoadjuvant Phase 2 Study Comparing the Effects of AR Inhibition With/Without SRC or MEK Inhibition in Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01995513",
      "title": "Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2023-09-18",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02034552",
      "title": "A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2019-07-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02091531",
      "title": "Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients",
      "status": "COMPLETED",
      "last_update": "2019-11-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02125084",
      "title": "Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-04",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02130700",
      "title": "Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer",
      "status": "COMPLETED",
      "last_update": "2018-05-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02130947",
      "title": "Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer Receiving Abiraterone or Enzalutamide",
      "status": "WITHDRAWN",
      "last_update": "2016-02-11",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02159690",
      "title": "A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and Degarelix in Men With Localized Prostate Cancer Pre-prostatectomy",
      "status": "WITHDRAWN",
      "last_update": "2015-01-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02199197",
      "title": "Radium Ra 223 With Enzalutamide Compared to Enzalutamide Alone in Men With Metastatic Castration Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-10-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02202447",
      "title": "Phase 1 of EC1169 In Patients With Recurrent MCRPC",
      "status": "COMPLETED",
      "last_update": "2019-02-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02203695",
      "title": "Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy",
      "status": "COMPLETED",
      "last_update": "2025-10-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02204072",
      "title": "BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2025-07-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02207504",
      "title": "Crizotinib in Combination With Enzalutamide in Metastatic Castration-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-01-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02256111",
      "title": "EXTEND Exercise Trial",
      "status": "COMPLETED",
      "last_update": "2019-04-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02268175",
      "title": "Enzalutamide/Leuprolide +/- Abiraterone/Pred in Prostate",
      "status": "COMPLETED",
      "last_update": "2022-04-19",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02278185",
      "title": "Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
      "status": "COMPLETED",
      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02288247",
      "title": "A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone",
      "status": "COMPLETED",
      "last_update": "2025-04-08",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02339168",
      "title": "Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-01",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02346578",
      "title": "Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.",
      "status": "COMPLETED",
      "last_update": "2021-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02407054",
      "title": "A Study of Enzalutamide and LY3023414 in Men With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02438007",
      "title": "A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC",
      "status": "TERMINATED",
      "last_update": "2023-03-15",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02441517",
      "title": "A Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer After Docetaxel and/or Cabazitaxel Treatment",
      "status": "TERMINATED",
      "last_update": "2018-04-19",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02446405",
      "title": "Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-02-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02522715",
      "title": "Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-24",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02525068",
      "title": "A Study of Enzalutamide in Combination With AZD5363 in Patients With mCRPC",
      "status": "UNKNOWN",
      "last_update": "2018-08-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02588001",
      "title": "Japanese Research for Patients With Non-metastatic Castration Resistant Prostate Cancer - Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2022-05-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02685267",
      "title": "Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2021-04-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02740985",
      "title": "A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies",
      "status": "COMPLETED",
      "last_update": "2023-05-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02758132",
      "title": "Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases",
      "status": "TERMINATED",
      "last_update": "2019-11-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02814968",
      "title": "PET/CT and WB MRI for Staging and Response in CRPC Patients Receiving Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2022-04-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02815033",
      "title": "Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2022-04-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02833883",
      "title": "Use of an Experimental Drug, CC-115, With Enzalutamide in Men With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-01-19",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02903160",
      "title": "Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)",
      "status": "COMPLETED",
      "last_update": "2024-02-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02935205",
      "title": "Enzalutamide and Indomethacin in Treating Patients With Recurrent or Metastatic Hormone-Resistant Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-11-29",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02975934",
      "title": "A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency",
      "status": "COMPLETED",
      "last_update": "2025-07-25",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02987543",
      "title": "Study of Olaparib (Lynparza\u2122) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)",
      "status": "COMPLETED",
      "last_update": "2023-10-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02991911",
      "title": "A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03002220",
      "title": "Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 Status",
      "status": "COMPLETED",
      "last_update": "2024-12-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03016312",
      "title": "A Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide in Participants With Metastatic Castration-Resistant Prostrate Cancer (mCRPC) After Failure of an Androgen Synthesis Inhibitor And Failure of, Ineligibility For, or Refusal of a Taxane Regimen",
      "status": "COMPLETED",
      "last_update": "2024-08-09",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03016741",
      "title": "Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-24",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03103724",
      "title": "A Phase II Study Evaluating the Efficacy of Enzalutamide and the Role of ARv7 in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients With Visceral Disease.",
      "status": "COMPLETED",
      "last_update": "2021-04-26",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03123978",
      "title": "Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03124615",
      "title": "Effect of Enzalutamide Dose Reduction on Fatigue, Cognition, and Drug Trough Levels in Patients With Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2017-04-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03148795",
      "title": "A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-04-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03170960",
      "title": "Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03177187",
      "title": "Combination Study of AZD5069 and Enzalutamide.",
      "status": "TERMINATED",
      "last_update": "2024-09-26",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03196388",
      "title": "Enzalutamide and External Beam Hypofractionated Radiotherapy For Intermediate Risk Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2018-01-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03246347",
      "title": "A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03297385",
      "title": "Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation",
      "status": "COMPLETED",
      "last_update": "2017-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03305224",
      "title": "The Combination Therapy With Ra-223 and Enzalutamide",
      "status": "UNKNOWN",
      "last_update": "2021-09-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03314324",
      "title": "A Study of Patient Preference Between ODM-201 and Enzalutamide in Men With Metastatic Castrate-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-08-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03336983",
      "title": "Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2024-08-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03338790",
      "title": "An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-01-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03418324",
      "title": "Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy",
      "status": "COMPLETED",
      "last_update": "2020-12-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03531827",
      "title": "Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment",
      "status": "TERMINATED",
      "last_update": "2022-07-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03551782",
      "title": "A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-02-25",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03556904",
      "title": "FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE)",
      "status": "COMPLETED",
      "last_update": "2026-01-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03569280",
      "title": "Evaluation of Safety and Efficacy of KPG-121 Plus Enzalutamide, Abiraterone or Apalutamide in CRPC Patients",
      "status": "COMPLETED",
      "last_update": "2023-07-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03674814",
      "title": "Study of Drug 1 (Enzalutamide) Plus Drug 2 (Relacorilant) for Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-03-31",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03690141",
      "title": "An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-06-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03709550",
      "title": "Enzalutamide and Decitabine in Treating Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2022-10-05",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03734653",
      "title": "Testosterone Therapy in Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-11-06",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03751436",
      "title": "Enzalutamide With Venetoclax in Treating Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-10-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03776968",
      "title": "A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics",
      "status": "COMPLETED",
      "last_update": "2024-10-23",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03778047",
      "title": "A Study Evaluating Enzalutamide Pharmacokinetics and Pharmacodynamics, and Related Changes After Drug Switch",
      "status": "COMPLETED",
      "last_update": "2020-11-03",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03811652",
      "title": "A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors",
      "status": "COMPLETED",
      "last_update": "2019-12-30",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03850795",
      "title": "HC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
      "status": "TERMINATED",
      "last_update": "2024-08-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03860987",
      "title": "Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-05-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03899467",
      "title": "The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC",
      "status": "COMPLETED",
      "last_update": "2024-02-12",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03939689",
      "title": "I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).",
      "status": "COMPLETED",
      "last_update": "2025-10-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03999515",
      "title": "Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-09-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04015622",
      "title": "PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04094519",
      "title": "A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-11-20",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04115007",
      "title": "Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-06-26",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04139772",
      "title": "Docetaxel or Hormone Therapy as Second Line Treatment in Patients With Asymptomatic or Oligosymptomatic Metastatic Castration-resistent Prostate Cancer (mCRPC) Progressing After Abiraterone or Enzalutamide.",
      "status": "UNKNOWN",
      "last_update": "2023-03-24",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04157088",
      "title": "Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)",
      "status": "TERMINATED",
      "last_update": "2023-08-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04191096",
      "title": "Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)",
      "status": "COMPLETED",
      "last_update": "2026-04-29",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04207255",
      "title": "Addition of Opaganib to Androgen Antagonists in Patients With mCRPC",
      "status": "COMPLETED",
      "last_update": "2024-09-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04237584",
      "title": "A Study Comparing ARB With Radium-223 vs ARB Therapy With Placebo and the Effect Upon Survival for mCRPC Patients",
      "status": "TERMINATED",
      "last_update": "2022-10-07",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04332744",
      "title": "Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)",
      "status": "COMPLETED",
      "last_update": "2025-05-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04381832",
      "title": "Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-07-22",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04471974",
      "title": "ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04478279",
      "title": "A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-09",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04597125",
      "title": "RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-06",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04628988",
      "title": "A Study of CC-90011 and Comparators in Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-09-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04647526",
      "title": "Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04655365",
      "title": "Detecting Metastases by PyL PET/CT in Subjects Starting Enzalutamide for Untreated Castration Resistant Prostate Cancer.",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04742972",
      "title": "Prostate PMSABR Study",
      "status": "WITHDRAWN",
      "last_update": "2022-12-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04821622",
      "title": "Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-04",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05011188",
      "title": "FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-08-27",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05022849",
      "title": "A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants",
      "status": "COMPLETED",
      "last_update": "2026-04-17",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05075577",
      "title": "EPI-7386 in Combination with Enzalutamide Compared with Enzalutamide Alone in Subjects with MCRPC",
      "status": "TERMINATED",
      "last_update": "2025-02-28",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05114746",
      "title": "Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan",
      "status": "COMPLETED",
      "last_update": "2026-05-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05191017",
      "title": "Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC",
      "status": "WITHDRAWN",
      "last_update": "2022-08-05",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05212857",
      "title": "Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2022-03-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05245435",
      "title": "Diagnostic and Prognostic Accuracy of FDHT-PET and Liquid Biopsies in Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2023-03-20",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05457257",
      "title": "Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-21",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05526248",
      "title": "A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05546268",
      "title": "Study of Oral MRT-2359 in Selected Cancer Patients",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-03-03",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05549778",
      "title": "Polaprezinc Treatment for Enzalutamide- or Abiraterone-resistant CRPC",
      "status": "COMPLETED",
      "last_update": "2023-07-11",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05588609",
      "title": "Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers",
      "status": "TERMINATED",
      "last_update": "2026-04-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05627752",
      "title": "Docetaxel Alone or in Combination With Enzalutamide for mCRPC Previously Treated With Abiraterone at mHSPC Stage",
      "status": "UNKNOWN",
      "last_update": "2024-02-28",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05700903",
      "title": "Contributions to Hypertension With Androgen Deprivation Therapy",
      "status": "TERMINATED",
      "last_update": "2026-09-02",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05730712",
      "title": "Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-06-09",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05733351",
      "title": "Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2025-09-15",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05771896",
      "title": "Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC",
      "status": "WITHDRAWN",
      "last_update": "2023-09-14",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06312670",
      "title": "Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-05-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06505278",
      "title": "The Impact of Medication Timing Adjustment on the Effect of Novel Hormonal Therapy",
      "status": "UNKNOWN",
      "last_update": "2024-08-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06551324",
      "title": "A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-11",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06734130",
      "title": "Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06764485",
      "title": "A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-08",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07172126",
      "title": "Clinical Trial to Evaluate the Tolerance of TQB3201 Tablets",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-09-15",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07268794",
      "title": "CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2025-12-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07512076",
      "title": "A Dose Optimization Study of Enzalutamide in Elderly Patients With Advanced Prostate Cancer",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-04-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07592910",
      "title": "A Study of Mevrometostat With Enzalutamide in People With Prostate Cancer Who Have Previously Received Androgen Receptor Pathway Inhibitor Therapy",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-05-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07620574",
      "title": "Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study",
      "status": "ENROLLING_BY_INVITATION",
      "last_update": "2026-08-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07645326",
      "title": "RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)",
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      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07730580",
      "title": "Study of XNW5004 Tablets in Advanced Prostate Cancer",
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      "last_update": "2026-07-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07802704",
      "title": "A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)",
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      "last_update": "2026-09-03",
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      "nct": "NCT00900614",
      "title": "Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer",
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      "nct": "NCT03678025",
      "title": "Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer",
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      "nct": "NCT04787744",
      "title": "Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer",
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      "nct": "NCT00001266",
      "title": "A Phase II Trial of Leuprolide + Flutamide + Suramin in Untreated Poor Prognosis Prostate Carcinoma",
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     {
      "nct": "NCT00002597",
      "title": "Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer",
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     {
      "nct": "NCT00002633",
      "title": "Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer",
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      "nct": "NCT00002855",
      "title": "Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer",
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     {
      "nct": "NCT00002889",
      "title": "Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00003026",
      "title": "Hormone Therapy in Treating Patients With Advanced Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00003124",
      "title": "Hormone Therapy Plus Radiation Therapy in Treating Patients With Prostate Cancer",
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     {
      "nct": "NCT00003323",
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      "nct": "NCT00003517",
      "title": "Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer",
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     {
      "nct": "NCT00003645",
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      "nct": "NCT00003653",
      "title": "Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer",
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     {
      "nct": "NCT00003734",
      "title": "Combination Hormone Therapy Followed by Radiation Therapy in Treating Patients With Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00004054",
      "title": "Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer",
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     {
      "nct": "NCT00005044",
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      "phase": "PHASE3",
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     {
      "nct": "NCT00006214",
      "title": "Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate",
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      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00006359",
      "title": "Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer",
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      "phase": "PHASE2",
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     {
      "nct": "NCT00023829",
      "title": "Adjuvant Radiation Therapy Plus Hormone Therapy Compared With Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer",
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      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00026377",
      "title": "SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer",
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     {
      "nct": "NCT00028769",
      "title": "S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer",
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     {
      "nct": "NCT00030654",
      "title": "Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer",
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     {
      "nct": "NCT00054106",
      "title": "Hormone Therapy and OGX-011 Before Radical Prostatectomy in Treating Patients With Prostate Cancer",
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     {
      "nct": "NCT00104741",
      "title": "Triptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer",
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      "last_update": "2021-02-21",
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     {
      "nct": "NCT00116220",
      "title": "Study of External Beam Radiation Therapy With and Without Hormonal Therapy to Treat Prostate Cancer",
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     {
      "nct": "NCT00170157",
      "title": "Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer",
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     {
      "nct": "NCT00175396",
      "title": "Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy",
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     {
      "nct": "NCT00223665",
      "title": "Effects of IAS in Men With Localized Biochemical Relapsed Prostate Cancer",
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     {
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      "title": "Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer",
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      "last_update": "2018-08-07",
      "phase": "PHASE2",
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     {
      "nct": "NCT00303784",
      "title": "Prostate Adenocarcinoma TransCutaneous Hormones",
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      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00309985",
      "title": "Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer",
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     {
      "nct": "NCT00388804",
      "title": "External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer",
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     {
      "nct": "NCT00450463",
      "title": "Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer",
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      "last_update": "2018-11-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00512668",
      "title": "Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer",
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      "last_update": "2013-01-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00528866",
      "title": "Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy",
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      "phase": "PHASE2",
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     {
      "nct": "NCT00567580",
      "title": "Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2025-05-09",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00651326",
      "title": "Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer",
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      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00767286",
      "title": "Goserelin, Flutamine, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer",
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      "last_update": "2014-01-28",
      "phase": "PHASE3",
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     {
      "nct": "NCT00769548",
      "title": "Radiation Therapy and Hormone Therapy in Treating Patients With Prostate Cancer",
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      "last_update": "2017-01-04",
      "phase": "PHASE3",
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     {
      "nct": "NCT00817739",
      "title": "Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c",
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      "last_update": "2015-07-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00936390",
      "title": "Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer",
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      "last_update": "2026-03-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT01011751",
      "title": "Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma",
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      "last_update": "2015-07-30",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT01122121",
      "title": "Leuprorelin Associated With Radiotherapy Versus Leuprorelin Alone in T3 - T4 or pT3 (on Biopsy) N0, M0 Prostate Cancer",
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      "last_update": "2015-07-29",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01546987",
      "title": "Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer",
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      "last_update": "2026-03-06",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01786265",
      "title": "Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer",
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      "last_update": "2026-08-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
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      "last_update": "2022-06-27",
      "phase": "PHASE2",
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     },
     {
      "nct": "NCT02341404",
      "title": "A Study of 2-hydroxyflutamide (Liproca Depot), Injected Into the Prostate in Patients With Localized Prostate Cancer",
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      "last_update": "2016-03-11",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02346578",
      "title": "Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.",
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      "last_update": "2021-09-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02454543",
      "title": "Impact of Radical Prostatectomy as Primary Treatment in Patients With Prostate Cancer With Limited Bone Metastases",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-01-12",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02742675",
      "title": "Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)",
      "status": "UNKNOWN",
      "last_update": "2020-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02799706",
      "title": "Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer",
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      "last_update": "2026-05-22",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02911350",
      "title": "Safety Study of Combination of Hormone Therapy, Paclitaxel and Radiation Therapy to Treat Prostate Cancer",
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      "last_update": "2017-10-02",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02918968",
      "title": "Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer",
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      "last_update": "2024-12-09",
      "phase": "PHASE4",
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     {
      "nct": "NCT03070886",
      "title": "Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT03488810",
      "title": "Apalutamide With Radiotherapy and Androgen Deprivation Therapy in Prostate Cancer",
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      "last_update": "2020-08-17",
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     {
      "nct": "NCT03507608",
      "title": "Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression",
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      "phase": "EARLY_PHASE1",
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     {
      "nct": "NCT04248621",
      "title": "Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04513717",
      "title": "Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial",
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     {
      "nct": "NCT05050084",
      "title": "Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial",
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     {
      "nct": "NCT05628363",
      "title": "Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer",
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     {
      "nct": "NCT05700903",
      "title": "Contributions to Hypertension With Androgen Deprivation Therapy",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05983198",
      "title": "Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT",
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      "last_update": "2026-09-11",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06601205",
      "title": "Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer.",
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      "last_update": "2024-09-19",
      "phase": "PHASE2/PHASE3",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00959959",
      "title": "ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer",
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     {
      "nct": "NCT01709734",
      "title": "A 2 Part, Phase 2 Trial of Galeterone in the Treatment of Castration Resistant Prostate Cancer",
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     {
      "nct": "NCT02438007",
      "title": "A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC",
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      "nct": "NCT00716794",
      "title": "A Phase I/II Study of HE3235 in Patients With Prostate Cancer",
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     {
      "nct": "NCT00859781",
      "title": "177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-04-08",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT00081172",
      "title": "Radiolabeled Monoclonal Antibody in Treating Patients With Progressive Metastatic Androgen-Independent Adenocarcinoma (Cancer) of the Prostate",
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     {
      "nct": "NCT00195039",
      "title": "Treatment With Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-J591) in Patients With Metastatic Prostate Cancer",
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     {
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      "title": "A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer",
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      "title": "Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer",
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      "title": "Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)",
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      "title": "A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-na\u00efve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study",
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      "nct": "NCT07219147",
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      "title": "Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial",
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      "title": "A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC",
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      "title": "Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function",
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      "title": "The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients with ACC- an Open, Non-commercial Clinical Trial",
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      "title": "Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer",
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      "title": "LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer",
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      "title": "NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.",
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      "title": "A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto\u00ae) in Patients With Non-curative Metastatic Prostate Cancer",
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      "title": "An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC",
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     {
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      "last_update": "2026-02-24",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT07047118",
      "title": "A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
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     {
      "nct": "NCT07650240",
      "title": "Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial",
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     {
      "nct": "NCT07682649",
      "title": "Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate Cancer",
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      "title": "A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer",
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      "title": "Impact of Peri-operative tEstosterone Levels on oNcological and Functional Outcomes in RadiCal prostatEctomy",
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      "title": "Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study",
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      "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer",
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      "title": "Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC",
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     {
      "nct": "NCT06733350",
      "title": "Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance",
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      "phase": "PHASE4",
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     {
      "nct": "NCT06922318",
      "title": "The COSMYC Trial (COmbined Suppression of MYC)",
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      "nct": "NCT07142551",
      "title": "Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response",
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      "last_update": "2026-03-11",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT07476001",
      "title": "Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC",
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      "nct": "NCT00006044",
      "title": "Testosterone in Treating Patients With Progressive Prostate Cancer That No Longer Responds to Hormone Therapy",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT00515112",
      "title": "Testosterone Replacement in Men With Non-Metastatic Castrate Resistant Prostate Cancer",
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      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT00586898",
      "title": "Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT00587431",
      "title": "Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer",
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      "last_update": "2023-11-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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      "nct": "NCT00853697",
      "title": "Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer",
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      "last_update": "2015-10-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT01084759",
      "title": "A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer",
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      "nct": "NCT01187485",
      "title": "A Randomized Study of Testosterone Replacement in Patients With Low Risk Hormone Refractory Prostate Cancer",
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      "phase": "PHASE1",
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     {
      "nct": "NCT01750398",
      "title": "Bipolar Androgen-based Therapy for Prostate Cancer (BAT)",
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     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
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      "phase": "PHASE2",
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     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
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      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT02995330",
      "title": "Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer",
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      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT03516812",
      "title": "Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer",
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      "last_update": "2025-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
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      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT03716739",
      "title": "Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency",
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      "last_update": "2026-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04134130",
      "title": "The Role of Follicle Stimulating Hormone in Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04424654",
      "title": "Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy",
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      "last_update": "2022-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT04558866",
      "title": "Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)",
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      "last_update": "2026-08-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05081193",
      "title": "Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06305598",
      "title": "Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07278362",
      "title": "Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-22",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     }
    ]
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      "nct": "NCT00020254",
      "title": "Vaccine Therapy Plus Sargramostim and Interleukin-2 Compared With Nilutamide Alone in Treating Patients With Prostate Cancer",
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     {
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     {
      "nct": "NCT00175396",
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     {
      "nct": "NCT00512668",
      "title": "Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer",
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     {
      "nct": "NCT00918385",
      "title": "Genomic Guided Therapy With Dasatinib or Nilutamide in Metastatic Castration-Resistant Prostate Cancer",
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     {
      "nct": "NCT01786265",
      "title": "Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer",
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     {
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      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
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     {
      "nct": "NCT03070886",
      "title": "Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery",
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     {
      "nct": "NCT01046916",
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     {
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     {
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     {
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      "title": "Phase Ib/II Study Evaluating Orteronel (Without Prednisone) Combined With Itraconazole In Men With Castration-Resistant Prostate Cancer (CRPC)",
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     {
      "nct": "NCT03211052",
      "title": "A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery Alone",
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      "phase": "PHASE2",
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      "title": "A Phase III Clinical Study of Rezvilutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer",
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      "title": "Clinical Study of Rezvilutamide Combined With Docetaxel Chemotherapy in the Treatment of Abiraterone-Resistant Prostate Cancer",
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      "last_update": "2026-08-31",
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      "nct": "NCT02012920",
      "title": "A Study to Evaluate Oral VT-464 in Patients With Castration-Resistant Prostate Cancer",
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     {
      "nct": "NCT02130700",
      "title": "Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer",
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     {
      "nct": "NCT02445976",
      "title": "Once-daily Oral Seviteronel in Patients With Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone.",
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      "title": "High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers",
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      "phase": "NA",
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     {
      "nct": "NCT05726292",
      "title": "A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer",
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      "nct": "NCT06059118",
      "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer",
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      "last_update": "2026-01-14",
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      "last_update": "2025-12-31",
      "phase": "PHASE2",
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      "title": "Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy",
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      "last_update": "2026-09-03",
      "phase": "PHASE2",
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      "nct": "NCT06100705",
      "title": "Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC",
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      "last_update": "2026-09-10",
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      "study_type": "INTERVENTIONAL"
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      "nct": "NCT06594926",
      "title": "Working Out M0 Bipolar Androgen Therapy",
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      "last_update": "2026-04-24",
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      "nct": "NCT06655259",
      "title": "Combination of TURP and Standard Systemic Therapy for MPCa",
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      "last_update": "2024-10-23",
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      "nct": "NCT06733350",
      "title": "Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance",
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      "last_update": "2026-05-14",
      "phase": "PHASE4",
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     {
      "nct": "NCT06824818",
      "title": "Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients",
      "status": "RECRUITING",
      "last_update": "2025-10-01",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06855277",
      "title": "Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-08-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06922318",
      "title": "The COSMYC Trial (COmbined Suppression of MYC)",
      "status": "RECRUITING",
      "last_update": "2026-06-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07142551",
      "title": "Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response",
      "status": "RECRUITING",
      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07299292",
      "title": "Castration With Abiraterone 250 mg Without LHRH Analogs or Blockers in Patients With Prostate Cancer Requiring Hormonal Intensification (Multicenter Phase 2)",
      "status": "RECRUITING",
      "last_update": "2025-12-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07302451",
      "title": "REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients)",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07393867",
      "title": "Androgen-responsive POSLUMA-guided Intra-prostatic Boost",
      "status": "RECRUITING",
      "last_update": "2026-05-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07476001",
      "title": "Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07552922",
      "title": "Determining INdividual Preferences for Gynecomastia avOidance (DINGO) - Stage 1",
      "status": "RECRUITING",
      "last_update": "2026-04-27",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07572760",
      "title": "Low to Moderate Load Power Training for Men With Metastatic Prostate Cancer.",
      "status": "RECRUITING",
      "last_update": "2026-05-07",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00005073",
      "title": "Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No Symptoms",
      "status": "TERMINATED",
      "last_update": "2013-05-01",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00006044",
      "title": "Testosterone in Treating Patients With Progressive Prostate Cancer That No Longer Responds to Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2013-01-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00056654",
      "title": "Study of a 6-Month Sustained-Release Formulation of Leuprolide Acetate in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2008-09-17",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00142506",
      "title": "Study of Sildenafil Citrate During and After Radiotherapy/Hormone Therapy for Erectile Function Versus Radiotherapy/Hormone Therapy for Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-10-20",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00175383",
      "title": "Long Acting LHRH Versus Short Acting LHRH in the Treatment of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-07-02",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00215657",
      "title": "Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients",
      "status": "TERMINATED",
      "last_update": "2011-05-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00220194",
      "title": "A Six-Month, Open-Label, Crossover Study Of the Maintenance Of Serum Testosterone And PSA Suppression After Switching Between Lupron 22.5 Mg And Eligard 22.5 Mg Or Zoladex 10.8 Mg And Eligard 22.5 Mg In Patients With Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-10-14",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00245518",
      "title": "Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy",
      "status": "COMPLETED",
      "last_update": "2017-10-13",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00283803",
      "title": "Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-08-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00450463",
      "title": "Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-11-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00515112",
      "title": "Testosterone Replacement in Men With Non-Metastatic Castrate Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2014-06-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00544440",
      "title": "An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma",
      "status": "COMPLETED",
      "last_update": "2014-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00577980",
      "title": "Testosterone in Castration-Resistant Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2013-04-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00586898",
      "title": "Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle",
      "status": "COMPLETED",
      "last_update": "2016-03-25",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00587431",
      "title": "Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-11-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00635856",
      "title": "Open Label Trial to Assess Iressa in Prostate Cancer Patients",
      "status": "COMPLETED",
      "last_update": "2009-04-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00685633",
      "title": "Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2013-08-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00728533",
      "title": "Open-Label, Randomised Parallel-Group Study",
      "status": "WITHDRAWN",
      "last_update": "2011-03-18",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00853697",
      "title": "Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2015-10-30",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00924469",
      "title": "A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone Acetate in Male Participants With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2013-04-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00928434",
      "title": "A Study of Degarelix in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-12-13",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01084759",
      "title": "A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-05-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01132404",
      "title": "Study in Men With Prostate Cancer to Assess the Safety, Pharmacokinetics and Testosterone-Lowering Efficacy of TAK-448",
      "status": "TERMINATED",
      "last_update": "2012-01-31",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01136226",
      "title": "Evaluate Recovery of Testosterone for Patients Using Eligard",
      "status": "COMPLETED",
      "last_update": "2018-10-24",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01187485",
      "title": "A Randomized Study of Testosterone Replacement in Patients With Low Risk Hormone Refractory Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2023-11-29",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01193244",
      "title": "Study Comparing Orteronel Plus Prednisone in Participants With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-05-17",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01326312",
      "title": "Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-06-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01344564",
      "title": "Initiation of Androgen Deprivation Therapy for Prostate Cancer Using Degarelix Followed by Leuprolide",
      "status": "COMPLETED",
      "last_update": "2013-03-18",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01394263",
      "title": "Study of Histrelin Subdermal Implant in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2024-01-02",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01415960",
      "title": "Efficacy and Safety of Leuprolide Acetate 22.5 mg Depot in Treatment of Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2017-03-03",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01420861",
      "title": "GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2023-10-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01615120",
      "title": "Study of the Effect of GTx-758 on Serum PSA and Testosterone in Men With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-03-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01696877",
      "title": "A Neoadjuvant Study of Androgen Ablation Combined With Cyclophosphamide and GVAX Vaccine for Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2019-03-28",
      "phase": "PHASE1/PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01750398",
      "title": "Bipolar Androgen-based Therapy for Prostate Cancer (BAT)",
      "status": "COMPLETED",
      "last_update": "2016-12-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01852864",
      "title": "Degarelix Before Radical Prostatectomy",
      "status": "UNKNOWN",
      "last_update": "2014-12-16",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01867424",
      "title": "Gadoxetate Enhanced Imaging Study to Detect Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-07-08",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01961843",
      "title": "Abiraterone Acetate for Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-11-25",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
      "status": "COMPLETED",
      "last_update": "2022-06-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
      "status": "COMPLETED",
      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02297386",
      "title": "[18F] Dihydro-testosterone Pet and MR Imaging In Patients With Localized Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2018-08-06",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02349386",
      "title": "Maintaining Suppression of Testosterone With Transdermal Estradiol Gel",
      "status": "TERMINATED",
      "last_update": "2022-03-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02430480",
      "title": "Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02737332",
      "title": "A Study to Evaluate Serum Testosterone Levels in Patients With Metastatic Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-11-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02867020",
      "title": "Study of Abiraterone Acetate Plus ADT Versus APALUTAMIDE Versus Abiraterone and APALUTAMIDE in Patients With Advanced Prostate Cancer With Non-castrate Testosterone Levels",
      "status": "COMPLETED",
      "last_update": "2021-07-07",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02995330",
      "title": "Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-02-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03141671",
      "title": "Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)",
      "status": "UNKNOWN",
      "last_update": "2024-05-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03298087",
      "title": "Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-08-01",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03361969",
      "title": "Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.",
      "status": "COMPLETED",
      "last_update": "2021-06-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03436745",
      "title": "The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females",
      "status": "TERMINATED",
      "last_update": "2026-06-26",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03511196",
      "title": "Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-04",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03516812",
      "title": "Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03662958",
      "title": "Comparison of a Novel Leuprolide With Market Leuprolide",
      "status": "UNKNOWN",
      "last_update": "2018-09-10",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03716739",
      "title": "Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency",
      "status": "COMPLETED",
      "last_update": "2026-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03734653",
      "title": "Testosterone Therapy in Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-11-06",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03767244",
      "title": "A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-28",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03777982",
      "title": "Conventional Androgen Deprivation Therapy (ADT) With or Without Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT",
      "status": "TERMINATED",
      "last_update": "2024-09-19",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04025372",
      "title": "INTREPId (INTermediate Risk Erection PreservatIon Trial)",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2025-12-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04060043",
      "title": "Pilot Study to Evaluate the Effects of a Generic Goserelin Acetate in Patients With Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2021-05-10",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04104893",
      "title": "A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04134130",
      "title": "The Role of Follicle Stimulating Hormone in Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04248621",
      "title": "Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients",
      "status": "UNKNOWN",
      "last_update": "2021-07-29",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04424654",
      "title": "Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy",
      "status": "COMPLETED",
      "last_update": "2022-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04455750",
      "title": "A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-02-05",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04558866",
      "title": "Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)",
      "status": "COMPLETED",
      "last_update": "2026-08-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04862091",
      "title": "Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA\u00ae in Patients With Metastatic Castration-resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2022-03-04",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05081193",
      "title": "Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05241860",
      "title": "Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)",
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      "last_update": "2026-08-31",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05249712",
      "title": "Efficacy and Safety of Darolutamide Combined With ADT in High-risk/Very High-risk Localized Prostate Cancer",
      "status": "UNKNOWN",
      "last_update": "2023-01-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05498272",
      "title": "Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-07-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05526248",
      "title": "A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide",
      "status": "COMPLETED",
      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05568537",
      "title": "Prostate MRI and Pylarify PSMA PET/CT",
      "status": "WITHDRAWN",
      "last_update": "2025-01-03",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
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     {
      "nct": "NCT05617885",
      "title": "Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2026-06-16",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06305598",
      "title": "Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer",
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      "last_update": "2026-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06795178",
      "title": "Efficacy, Safety, and Pharmacokinetics of FP-014, 11.25 mg in Patients With Advanced Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2025-04-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06795191",
      "title": "Efficacy, Safety, and Pharmacokinetics of FP-014, 22.5 mg in Patients With Advanced Prostate Cancer",
      "status": "WITHDRAWN",
      "last_update": "2025-04-27",
      "phase": "PHASE3",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07069465",
      "title": "Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging",
      "status": "COMPLETED",
      "last_update": "2025-07-16",
      "phase": "EARLY_PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07278362",
      "title": "Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-22",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07335796",
      "title": "A Study of BMS986365 in Combination With Degarelix in People With Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-09-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07535905",
      "title": "Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Cancer Patients",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-06-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07649421",
      "title": "PSMA PET/CT-Guided SBRT Plus Darolutamide in mHSPC",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ]
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   "TESTOSTERONE CYPIONATE": {
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     {
      "nct": "NCT04363164",
      "title": "Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression",
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      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06039371",
      "title": "Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study",
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      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06059118",
      "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer",
      "status": "RECRUITING",
      "last_update": "2026-01-14",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06100705",
      "title": "Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-09-10",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06922318",
      "title": "The COSMYC Trial (COmbined Suppression of MYC)",
      "status": "RECRUITING",
      "last_update": "2026-06-18",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07142551",
      "title": "Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response",
      "status": "RECRUITING",
      "last_update": "2026-03-11",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07476001",
      "title": "Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-05-15",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01084759",
      "title": "A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2016-05-09",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01750398",
      "title": "Bipolar Androgen-based Therapy for Prostate Cancer (BAT)",
      "status": "COMPLETED",
      "last_update": "2016-12-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
      "status": "COMPLETED",
      "last_update": "2022-06-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
      "status": "COMPLETED",
      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02995330",
      "title": "Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer",
      "status": "TERMINATED",
      "last_update": "2024-02-13",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03516812",
      "title": "Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03716739",
      "title": "Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency",
      "status": "COMPLETED",
      "last_update": "2026-07-16",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04424654",
      "title": "Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy",
      "status": "COMPLETED",
      "last_update": "2022-08-03",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04558866",
      "title": "Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)",
      "status": "COMPLETED",
      "last_update": "2026-08-28",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06305598",
      "title": "Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT07278362",
      "title": "Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance",
      "status": "NOT_YET_RECRUITING",
      "last_update": "2026-07-22",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     }
    ]
   },
   "TESTOSTERONE ENANTHATE": {
    "n": 7,
    "n_observational": 0,
    "n_active": 3,
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    "trials": [
     {
      "nct": "NCT03522064",
      "title": "Bipolar Androgen Therapy + Carboplatin in mCRPC",
      "status": "RECRUITING",
      "last_update": "2026-04-23",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT04363164",
      "title": "Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression",
      "status": "RECRUITING",
      "last_update": "2026-07-17",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06594926",
      "title": "Working Out M0 Bipolar Androgen Therapy",
      "status": "RECRUITING",
      "last_update": "2026-04-24",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT01750398",
      "title": "Bipolar Androgen-based Therapy for Prostate Cancer (BAT)",
      "status": "COMPLETED",
      "last_update": "2016-12-05",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02090114",
      "title": "RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)",
      "status": "COMPLETED",
      "last_update": "2022-06-27",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT02286921",
      "title": "Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance",
      "status": "COMPLETED",
      "last_update": "2020-11-06",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03516812",
      "title": "Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ]
   },
   "TESTOSTERONE PROPIONATE": {
    "n": 7,
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    "n_active": 3,
    "n_withdrawn": 0,
    "trials": [
     {
      "nct": "NCT06039371",
      "title": "Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study",
      "status": "RECRUITING",
      "last_update": "2026-07-21",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06733350",
      "title": "Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance",
      "status": "RECRUITING",
      "last_update": "2026-05-14",
      "phase": "PHASE4",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT00006044",
      "title": "Testosterone in Treating Patients With Progressive Prostate Cancer That No Longer Responds to Hormone Therapy",
      "status": "COMPLETED",
      "last_update": "2013-01-18",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03516812",
      "title": "Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-29",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT03554317",
      "title": "COMbination of Bipolar Androgen Therapy and Nivolumab",
      "status": "COMPLETED",
      "last_update": "2024-02-20",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05081193",
      "title": "Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT06305598",
      "title": "Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer",
      "status": "ACTIVE_NOT_RECRUITING",
      "last_update": "2026-08-07",
      "phase": "PHASE1",
      "study_type": "INTERVENTIONAL"
     }
    ]
   },
   "TESTOSTERONE UNDECANOATE": {
    "n": 2,
    "n_observational": 0,
    "n_active": 0,
    "n_withdrawn": 0,
    "trials": [
     {
      "nct": "NCT04134130",
      "title": "The Role of Follicle Stimulating Hormone in Advanced Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2020-01-22",
      "phase": "NA",
      "study_type": "INTERVENTIONAL"
     },
     {
      "nct": "NCT05081193",
      "title": "Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer",
      "status": "COMPLETED",
      "last_update": "2025-09-22",
      "phase": "PHASE2",
      "study_type": "INTERVENTIONAL"
     }
    ]
   }
  }
 }
}