Sr. Scientist, Cell Therapy Analytical Development

Job Title

A successful candidate will be expected to have a solid background in developing various bioassays to support release and characterization of cell therapy products. Also, a depth technical knowledge and experience in method qualification, validation, and transfer to internal or external partners is required.

Responsibilities

• Develop accurate, precise and robust functional (flow cytometry, ELISA, Western) and molecular (ddPCR, RT-qPCR) analytical methods for in process control and final product release.
• Design, test, and implement fit-for-purpose analytical assays to support the product quality and impurity characterization in cell therapy product development.
• Perform and coordinate testing to support research development, process development, and method troubleshooting across functional groups.
• Execute analytical method qualification and technology transfer to QC and partners.
• Providing technical support to QC laboratories, and assisting in investigations
• Write development/technical reports, SOPs and test procedures.
• Review and discuss analytical results and conclusions both orally and in writing.
• Work in a team-based structure and interface with research and process development departments.
• Maintain and ensure safe laboratory environment and work practices.
• Ensure timely completion of testing and tasks as assigned.

  Qualifications and Requirements

  • Master with 5+ yrs. or PhD with 2+ yrs. experience in industry or academia with a focus on cell and gene therapy products.
  • Extensive hands-on cell-based assay development experience.
  • Hands-on operation and data analysis experience with immune cell-based assay and flow cytometry (FACS) is required.
  • High level of proficiency in molecular biology (e.g. PCR, qPCR, ddPCR, RT-qPCR) is preferred.
  • Understanding of ICH guidelines, method qualification and validation preferred.
  • Strong desire to learn and troubleshoot technical challenges.
  • Collaborative mindset with strong communication skills, and the ability to effectively present data, write reports and document test procedures.
  • Excellent presentation skills, written and verbal.
  • Demonstrated ability to work in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlines.

    What We Offer To Our Valued Employees

    • Market competitive compensation package including performance-based annual bonus scheme
    • Company shares (generous welcome grant!)
    • In-house and external learning and development opportunities
    • Fantastic benefits program and keep improving!
    • Plus you get to work with a dynamic team of collaborative, supportive, inclusive, and fun professionals whose mission is clear: Cancer has no borders and neither do we.
    • Join us and Make momentum in your career!

      BeOne Global Competencies

      When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

      • Fosters Teamwork
      • Provides and Solicits Honest and Actionable Feedback
      • Self-Awareness
      • Acts Inclusively
      • Demonstrates Initiative
      • Entrepreneurial Mindset
      • Continuous Learning
      • Embraces Change
      • Results-Oriented
      • Analytical Thinking/Data Analysis
      • Financial Excellence
      • Communicates with Clarity