Research assistant

Research Assistant

Do you want to contribute to top quality medical research?

Applied developmental neurobiology group led by Carl Sellgren is looking for a highly motivated research assistant with background in cell and molecular biology to contribute towards research on neuropsychiatric disorders. The position will be placed in the Department of Physiology and Pharmacology at the Karolinska Institutet, which has a collegial, international and dynamic research environment. We offer an exciting, open, and collaborative research work environment where you can make a difference.

Your Mission

The ideal candidate will be highly motivated, detail-oriented, and eager to contribute to cutting-edge research in neurogenetics and stem cell biology.

The candidate will join a multidisciplinary team working on genetic screening projects aimed at furthering our understanding of the genetic basis of neurological and psychiatric disorders. The successful candidate's responsibilities will include:

• In vitro culture of human pluripotent stem cells (hPSCs), including maintenance and differentiation into various central nervous system (CNS) cell types using both 2D and 3D differentiation protocols.
• Characterization and analysis of hPSC-derived neuronal and non-neuronal CNS cells using techniques such as microscopy and electrophysiological assays.
• Preparation of samples for single-cell RNA sequencing (scRNA-seq).
• Application of standard molecular biology techniques.
• Data analysis and documentation.

  Your Profile

  • Applicants must hold a Master degree (or equivalent) in a field relevant for the work.
  • Applicants must have experience in eukaryotic cell culture.
  • Experience in human pluripotent stem cell culture and differentiation is preferred.
  • Familiarity with standard molecular biological techniques, including molecular cloning and basic molecular analyses at the transcriptional and protein levels.
  • Experience with genetic screening using CRISPR/Cas9 is desirable.
  • Strong interpersonal skills, with ability to work independently as well as collaboratively as part of a team.

    What Do We Offer?

    A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.