Research Lab Manager – Gastroenterology (Hepatology)

Laboratory Scientist

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at WashU Medicine in St. Louis is seeking motivated and creative scientists to join our interdisciplinary research program investigating the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection. Our long-term goal is to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver related morbidity and mortality.

Our laboratory has a strong history of developing innovative human models of viral infection. We were among the first groups to establish hepatitis B and hepatitis C virus infection models using stem cell-derived hepatocytes, and we have continued to combine these systems with primary human hepatocytes, CRISPR/Cas9 gene editing, and genetically distinct HBV clones to dissect the host and viral factors that determine infection and persistence. Recent work from the laboratory, published in Cell, identified a nucleosome-level molecular switch that primes and influences HBV infection.

Performs, oversees and coordinates research projects. Oversees entire laboratory setting to promote smooth operation, regulatory compliance and interaction with other laboratories.

Primary Duties & Responsibilities:

• With principal investigator, designs, performs and evaluates research procedures.
• Assists with grant preparation and journal article submission.
• Develops and implements policies and procedures. Provides comprehensive direction to laboratory personnel.
• Hires, trains and evaluates the performance of laboratory personnel.
• Oversees and directs all support activities of the lab including human resources, budgets, facility maintenance, purchasing, supplies, materials and equipment.
• Researches and recommends new methods and procedures to maintain current capabilities, quality and standards.

  Working Conditions:

  • Works in a laboratory environment with potential exposure to biological and chemical hazards.
  • Must be physically able to wear protective equipment and to provide standard care to research animals.

    The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

    WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

    Analytical Problem Solving, Communication, Prioritization

    R12

    $63,400.00 – $115,000.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

    All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

    All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

    Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University's policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.