Sr. Scientist, Discovery Oncology
About this role
Discovery Oncology Scientist
We are seeking a highly qualified scientist with a strong background in oncology to join our Discovery Oncology team in Boston. The successful candidate will have a proven track record of innovative, collaborative, and rigorous research. Primary responsibilities include providing scientific leadership from the bench, combining deep cancer biology expertise with creativity and rigor to drive the experimental strategy, and effectively communicating with multidisciplinary teams in the early discovery pipeline.
The specific responsibilities of the candidate include but are not limited to:
- Scientific leadership through the development and implementation of multiple impactful experimental approaches, technologies, or capabilities to drive target validation, pathway interrogation, and mechanistic studies
- Contribute to therapeutic mechanistic understanding, biomarker discovery, and preclinical candidate characterization
- Monitor, review and critically interpret published literature to guide internal research
- Effectively communicate experimental findings to appropriate stakeholders.
- Leverage broad scientific expertise and deep domain knowledge to influence scientific direction
Education:
- PhD or equivalent in oncology, biology, biochemistry, immunology, or related STEM discipline and 0 years of experience; MS with 5+ yrs of experience; OR BS with 7+ yrs working experience in a pharma or biotech setting.
Required:
- Demonstrated ability to work independently to create and drive experimental strategy, interpret data, troubleshoot, and define critical next steps.
- Strong experience in molecular and cellular biology techniques with an emphasis on mammalian cell culture, western blot, ELISA/Mesoscale, flow cytometry, qPCR, stable cell line generation, CRISPR.
- Strong team player and experienced working with collaborative cross functional teams.
Preferred experience and skills:
- Previous experience working with different therapeutic modalities.
- Experience integrating data from multiple experimental approaches to build mechanistic understanding, generate hypotheses, and connect experimental findings to broader program objectives to enable effective decision-making across stakeholders
- Prior oncology research experience
Required Skills: Assay Development, Biology, Cancer Therapy, Cell Culture Techniques, Design of Experiments (DOE), Drug Target Identification, Flow Cytometry, Immunoassays, Independent Thinking, Mechanism of Action, Molecular Biology, Oncology, Target Discovery
Preferred Skills:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
The salary range for this role is $119,100.00 – $187,500.00
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
- PhD or equivalent in oncology, biology, biochemistry, immunology, or related STEM discipline and 0 years of experience; MS with 5+ yrs of experience; OR BS with 7+ yrs working experience in a pharma or biotech setting.
Details
Organization
Merck
Location
United States (US)
Position type
Research
Posted
September 8, 2026
Source
jobRxiv
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