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Senior Research Associate, Flow Cytometry

🏛️ Beamtherapeutics 📍 Cambridge, MA 🗓️ Posted 16 hours, 23 minutes ago

About this role

Company Overview:

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Primary Responsibilities:

  • Supporting all internal/external research programs.
  • Execute specimen preparation, staining and sample acquisition of flow cytometric data.
  • Perform cell sorting on BD FACS Melody, FACSAria Fusion or BD FACS Symphony S6.
  • Design, plan, and execute assay development and/or platform development within the core flow cytometry group and cross-functionally.
  • Perform flow data analyses and interpretation, and present data at group meetings.
  • Maintain electronic notebook record of performed experiments.
  • Provide basic training to researcher on various flow cytometers and cell sorters.
  • Evaluate and troubleshoot instrument issues.
  • Assist in coordinating core lab logistics (e.g. user scheduling, vendor/maintenance calls, etc.)

    Qualifications:

    • Bachelor’s degree (or foreign equivalent) with five years of progressive, post-baccalaureate experience, or a master’s degree (or foreign equivalent) with two years of progressive, post-baccalaureate experience, with degree fields in biology, immunology, cell biology, molecular biology, pharmaceutical sciences, biochemistry, biomedical engineering, biotechnology or a closely related field, and demonstrated experience in all of the following:

      (a) performing high-parameter flow cytometry analyses of hematopoietic stem and immune cell subsets, and,

      (b) designing and executing flow-based assay development for preclinical or translational research; and,

      (c) conducting quantitative flow cytometry data analysis using FlowJo or FCS Express; and,

      (d) troubleshooting instrument performance and coordinating maintenance; and,

      (e) operating and maintaining high-parameter flow cytometers and cell sorters.

      Other Information: