Postdoc Position – Cancer Biology

The Chen lab at the Department of Cancer Sciences, Cleveland Clinic, is seeking a self-motivated postdoc fellow to join our team. The ideal applicants should receive a doctoral degree (PhD or MD/PhD) recently or will receive doctoral degree soon. Experience in cancer biology, tumor immunology, cancer genetics/epigenetics, and bioinformatics is preferred. Preference will be given to candidates with first-author publications in peer-reviewed journals. Interested applicants please send your curriculum vitae, cover letter, and names and contact information of three references to Dr. Chen at [email protected]

About the PI and the lab

The PI of the lab is Dr. Peiwen Chen, who received PhD degree from University of Padova, Italy, in 2015 and finished his postdoc training at MD Anderson Cancer Center in 2020. Dr. Chen joined the Department of Cancer Biology, Cleveland Clinic, as an Associate Professor in July 2024 from Feinberg School of Medicine, Northwestern University, where he was a tenure-track Assistant Professor since October 2020. Dr. Chen’s laboratory at Cleveland Clinic studies the molecular and biological processes governing the development of primary (e.g., glioblastoma) and metastatic (brain metastatic breast cancer) brain cancers and aims to develop novel therapeutic strategies for patients with these diseases. Specifically, Dr. Chen’s lab focuses on: 1_) characterizing the molecular mechanisms governing the symbiotic interactions between cancer cells/cancer stem cells and immune cells (including myeloid cells and T cells) in brain cancers; and 2) developing therapeutic approaches to target the tumor-immune symbiosis, and testing whether targeting the symbiosis can improve the effectiveness of immunotherapy in brain cancers; and 3) developing/using novel platforms to identify therapeutic targets in brain tumors under specific genetic backgrounds. The work conducted in the lab has been published in high-impact journals, including Nature Cancer, Nature Immunology, Nature Communications, Journal of Clinical Investigation, Cancer Research, Cell Reports Medicine,_ and Cell Reports. Ongoing research projects in the lab are supported by several highly competitive grants. For more information, please refer to following recent publications and our labpage: https://www.lerner.ccf.org/cancer-sciences/peiwen-chen/

About Cleveland Clinic

Cleveland Clinic ranks one of two best hospitals in the World for Sixth Consecutive Year by the Newsweek, and in the United States by the U.S. News & World Report. Cleveland Clinic Research is home to laboratory-based research at Cleveland Clinic. Scientists at Cleveland Clinic have unrivaled access to cancer patient samples and data, which play a significant role in answering fundamental biological questions and performing translational research.

Compensation and benefits

Postdoctoral salary adheres to NIH standards and is commensurate with prior research experience. Additionally, the Cleveland Clinic offers excellent insurance and benefits.