IRF3 and type I interferons fuel a fatal response to myocardial infarction
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE106473_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA416978 and SRA study SRP124082. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 9 more — browse all 9 samples with per-sample file links →
- GSE106471 IRF3 and type I interferons fuel a fatal response to myocardial infarction [bulk RNA-Seq] 6 samples shares irf3, interferons, myocardial, infarction, fatal, type, fuel
- GSE252027 Temporal co-regulation of microRNA arms among cell types after myocardial infarction [RNA-Seq] 96 samples shares myocardial, infarction, type
- GSE306097 Distinct immunometabolic signatures of type 1 versus type 2 diabetes in a murine model of myocardial infarction 55 samples shares myocardial, infarction, type
- GSE276317 Sleep fragmentation aggravates myocardial infarction through promoting type I interferon-mediated SiglecFhi neutrophil expansion 6 samples shares myocardial, infarction, type
- GSE252028 A cell type-specific expression atlas of small and total RNA in the heart after myocardial infarction 192 samples shares myocardial, infarction, type
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares interferons, type
- GSE291292 Navarixin alleviates cardiac remodeling after myocardial infarction by decreasing neutrophil infiltration and the inflammatory response 10 samples shares myocardial, infarction
- GSE254698 Myocardial infarction accelerates hepatic pathological progression of NASH by triggering immunoinflammatory response and induction of periostin 6 samples shares myocardial, infarction
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.