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A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

GSE11892 Homo sapiens Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 11 samples Submitted 2008/07/03 Platform GPL6104Platform GPL9052
Summary
Transcriptome of HEK and B cells were analyzed by microarray and RNA-Seq parallely. Both platforms were then compared in terms of sensitivity. To assess whether values were a reliable indicator of gene activity, we correlated these values with hypophosphorylated RNA polymerase II (PolIIa) occupancy, used as a landmark of transcription initiation. For HEK, we identified PolIIa islands by chromatin immunoprecipitation and sequencing (ChIP-Seq).
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Also filed as BioProject PRJNA105719 and SRA study SRP000714. Searching any of these in the dataset finder brings you back here.

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