DNA Methylation Identifies Genetically and Prognostically Distinct Subtypes of Myelodysplastic Syndromes
DNA methylation · human · 141 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Topic
- Myelodysplastic syndromesThis series is part of our curated briefing on it.
- Samples
- 141 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE129828_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA532913. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 141 more — browse all 141 samples with per-sample file links →
- GSE256396 Somatic mutations and DNA methylation identify a subgroup of poor prognosis within lower risk myelodysplastic syndromes 374 samples same disease briefing · shares myelodysplastic, methylation, syndromes
- GSE261339 Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia 18 samples same disease briefing · shares myelodysplastic, identifies, syndromes
- GSE290183 Distinct routes of clonal progression in SF3B1-mutant myelodysplastic syndromes 15 samples same disease briefing · shares myelodysplastic, syndromes, distinct
- GSE15688 Acquired mutations in TET2 are common in myelodysplastic syndromes 122 samples same disease briefing · shares myelodysplastic, syndromes
- GSE275000 Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs 104 samples same disease briefing · shares methylation, distinct
- GSE31174 Affymetrix SNP array data for myelodysplastic syndromes (MDS) and related neoplasms 58 samples same disease briefing · shares myelodysplastic, syndromes
- GSE211032 Expression Analysis (RNA-Seq) of adult Myelodysplastic Syndromes (MDS)/Acute Myeloid Leukemia (AML) with isolated monosomy 7 compared to controls 45 samples same disease briefing · shares myelodysplastic, syndromes
- GSE272173 Molecular profiling of pre-and post-5-azacytidine myelodysplastic syndrome samples identifies predictors of response 34 samples same disease briefing · shares myelodysplastic, identifies
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.