GEO series
Investigation of ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines
GSE130956
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/04/30
GPL21697
Summary
We identified that upregulation of ST8SIA1 promotes melanoma brain metastasis. The goal of this RNA-seq is to analyze the ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines (DP-0574 and WP-0614 cell lines) In vitro functional studies demonstrate that ST8SIA1 overexpression promotes cell proliferation and colony formation and that this can be halted by icaritin treatment.
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