Mutant Kras co-opts a progenitor-derived enhancer network to initiate pancreatic tumorigenesis
Direct links to NCBI, no account and no request form: the whole study as GSE134236_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 166 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA554369 and SRA study SRP254548. Searching any of these in the dataset finder brings you back here.
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- GSE248948 Spatiotemporal control of SMARCA5 by a MAPK-RUNX1 axis distinguishes mutant KRAS-driven pancreatic malignancy from tissue regeneration 170 samples
- GSE248942 Spatiotemporal control of SMARCA5 by a MAPK-RUNX1 axis distinguishes mutant KRAS-driven pancreatic malignancy from tissue regeneration (ATAC-Seq) 123 samples
- GSE157927 Triptolide Targets Super-Enhancer Networks in Pancreatic Cancer Cells and Cancer Associated Fibroblasts 81 samples
- GSE289420 Astrocyte-derived cholesterol drives synaptic gene expression in developing neurons and reciprocal astrocytic transcriptional programs 416 samples
- GSE287736 Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytes 138 samples
- GSE287355 An EZH2—SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis 79 samples
- GSE292300 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: ChIP-seq 76 samples
- GSE315648 Sensitive monitoring of enhancer and noncoding RNA transcription via ribozyme-assisted RNA editing 71 samples
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