GEO series
HDAC inhibition drives treatment duration-dependent changes in proliferation and effector function of tumor-infiltrating CD8 T cells.
GSE140285
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2025/11/01
GPL19057
Summary
To determine how Entinostat (ENT) treatment affected tumor-infiltrating CD8 T cells, we treated TS/A tumor-bearing mice with vehicle or ENT daily beginning at day 7 and performed RNAseq on CD8 T cells isolated from tumors on day 10 and day 17. These data show that ENT progressively altered both the function and distribution of infiltrating CD8 T cells.
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