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RNA sequencing of the left ventricle from non-failing donors and heart failure samples from the MAGNet consortium

GSE141910 Homo sapiens Expression profiling by high throughput sequencing 366 samples Submitted 2019/12/13 Platform GPL16791
Summary
The Myocardial Applied Genomics Network (MAGNet; www.med.upenn.edu/magnet), collects and banks human cardiac tissue for genomic research. All subjects or next of kin provided written informed consent for tissue donation and analyses and all study protocols were approved by relevant institutional review boards. Left ventricular free-wall tissue was harvested at the time of cardiac surgery from subjects with heart failure undergoing transplantation and from unused donor hearts with apparently normal function. The heart was perfused with cold cardioplegia prior to cardiectomy to arrest contraction and prevent ischemic damage, and tissue specimens were frozen in liquid nitrogen.
Published in
Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy
Flam E, Jang C, Murashige D et al. · Nature cardiovascular research 2022 · PMID 36776621 · doi:10.1038/s44161-022-00117-6
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Direct links to NCBI, no account and no request form: the whole study as GSE141910_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 366 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA595151 and SRA study SRP237337. Searching any of these in the dataset finder brings you back here.

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