GEO series
Changes in global open chromatin structure caused by acute deletion of TERT in spermatogonial stem cells
GSE145658
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
22 samples
2024/07/11
GPL21103
Summary
To understand the catalytic activity-independent functions of TERT in global chromatin structure, we acutely deleted TERT in spermatogonial stem cell (SSC) populations in the testis, and performed ATAC-seq. We find significant global loss of open chromatin structure in TERT-deleted SSC populations.
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