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Genome wide mapping of the effects of SMAD2/3 ligand treatment upon the distribution of senescence associated transcription factors

GSE146569 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 7 samples Submitted 2025/05/30 Platform GPL16791
Summary
Analysis of SMAD2/3 and NFI binding in replicative senescent BJ fibroblasts upon treatment with SAMD2/3 regulating ligands.
Published in
Ligand-specific regulation of a binary enhancer code dictating cellular senescence
Suter T, Friedman MJ, Tazearslan C et al. · Proceedings of the National Academy of Sciences of the United States of America 2025 · PMID 40493192 · doi:10.1073/pnas.2506321122
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Also filed as BioProject PRJNA610865 and SRA study SRP251898. Searching any of these in the dataset finder brings you back here.

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