GEO series

Expression data from human foetal neural stem (NS) cell lines and human glioma neural stem (GNS) cell lines

GSE15209 Homo sapiens Expression profiling by array 20 samples Submitted 2009/03/13 Platform GPL570

Summary

Gliomas have been proposed to be driven by a population of neural stem-like cells. We isolated a panel of novel human glioma cell lines using adherent neural stem cell conditions. The normal human foetal (hf) NS cells and the tumorigenic glioma NS cell lines were expanded using growth factors EGF and FGF in adherent culture conditions. In these conditions apoptosis and differentiation are suppressed resulting in more homogeneous populations of stem cells than has been reported previously. We included parallel primary biopsies of non-malignant brain tissue ('Normal Brain').

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Direct links to NCBI, no account and no request form: the whole study as GSE15209_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 20 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA116447. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 19497285) ↗

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