Epigenetic regulation of the mesenchymal niche during pancreatic epithelial development
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 14 distinct titles, 4 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE155875_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA655909 and SRA study SRP276667. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 18 sample titles: 14 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM4714995 ctl_panc_rna_rep1
- GSM4714996 ctl_panc_rna_rep2
- GSM4714997 eed_panc_rna_rep1
- GSM4714998 eed_panc_rna_rep2
- GSM4714999 ctl_panc_atac_rep1
- GSM4715000 ctl_panc_atac_rep2
- GSM4715001 eed_panc_atac_rep1
- GSM4715002 eed_panc_atac_rep2
- GSM4715003 GSM4430322_WT_Int_ATAC_rep1_re-analyzed
- GSM4715004 GSM4430323_WT_Int_ATAC_rep2_re-analyzed
- GSM4715005 GSM4430324_KO_Int_ATAC_rep1_re-analyzed
- GSM4715006 GSM4430325_KO_Int_ATAC_rep2_re-analyzed
- GSM4715007 GSM4430326_WT_St_ATAC_rep1_re-analyzed
- GSM4715008 GSM4430327_WT_St_ATAC_rep2_re-analyzed
- GSM4715009 GSM4430328_KO_St_ATAC_rep1_re-analyzed
- GSM4715010 GSM4430329_KO_St_ATAC_rep2_re-analyzed
- GSM4715011 ctrl_panc_scrna
- GSM4715012 eed_panc_scrna
- GSE248586 A conserved epithelial wound-like transcriptional program driven by FOSL1 underlies malignant progression of pancreatic ductal adenocarcinoma 57 samples shares pancreatic, epithelial
- GSE248585 A conserved epithelial wound-like transcriptional program driven by FOSL1 underlies malignant progression of pancreatic ductal adenocarcinoma (ssRNA-Seq) 46 samples shares pancreatic, epithelial
- GSE287625 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity 18 samples shares pancreatic, epithelial
- GSE249931 Temporal single-cell profiling of distinct mesenchymal, epithelial, endothelial, and immune cell lineages in the lung after injury 17 samples shares mesenchymal, epithelial
- GSE266584 Epigenetic and transcriptional regulation of dendritic cell development and anti-tumor function by HDAC1 34 samples shares epigenetic
- GSE279810 Genetic and epigenetic regulation of Treg cell fitness by autism-related chromatin remodeler CHD8 18 samples shares epigenetic
- GSE236580 Adipose tissue retains an epigenetic memory of obesity after weight loss 135 samples shares epigenetic
- GSE247970 Cell of origin epigenetic priming determines susceptibility to Tet2 oncogenic mutation 76 samples shares epigenetic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.