Functional heterogeneity of dentate gyrus mossy cells along the longitudinal axis of the hippocampus
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × Mossy cells_Dorsal vs 5 × Mossy cells_VentralGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Translational Profiling of Drd2-Expressing Populations Reveals Molecular Heterogeneity of Dentate Gyrus Mossy Cells along the Dorsoventral AxiseNeuro · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE156004_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA656298 and SRA study SRP276952. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM4718842 Mossy cells_Dorsal_rep1 Mossy cells_Dorsal
- GSM4718843 Mossy cells_Dorsal_rep2 Mossy cells_Dorsal
- GSM4718844 Mossy cells_Dorsal_rep3 Mossy cells_Dorsal
- GSM4718845 Mossy cells_Dorsal_rep4 Mossy cells_Dorsal
- GSM4718846 Mossy cells_Dorsal_rep5 Mossy cells_Dorsal
- GSM4718847 Mossy cells_Ventral_rep1 Mossy cells_Ventral
- GSM4718848 Mossy cells_Ventral_rep2 Mossy cells_Ventral
- GSM4718849 Mossy cells_Ventral_rep3 Mossy cells_Ventral
- GSM4718850 Mossy cells_Ventral_rep4 Mossy cells_Ventral
- GSM4718851 Mossy cells_Ventral_rep5 Mossy cells_Ventral
- GSE104323 Transcriptome analysis of single cells from the developing mouse dentate gyrus 232 samples shares dentate, gyrus
- GSE273494 Pattern separation memory requires Cerebellin 4-Neogenin 1 signaling at dentate gyrus synapses 36 samples shares dentate, gyrus
- GSE309750 Translational reprogramming of dentate gyrus peptidergic circuitry gates antidepressant efficacy 34 samples shares dentate, gyrus
- GSE317534 Differential Circadian Time Modulates of Dentate Gyrus and CA1 Excitation-Inhibition Balance and Seizure Threshold. 12 samples shares dentate, gyrus
- GSE290434 A stress response axis in tumor-associated macrophages dictates phenotype heterogeneity and immunotherapy evasion 21 samples shares heterogeneity, axis
- GSE233363 Multimodal transcriptomics reveal neurogenic aging trajectories and age-related regional inflammation in the dentate gyrus 20 samples shares dentate, gyrus
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares hippocampus
- GSE284500 Transcriptional profiling of hippocampus from a zQ175 KI mouse model of Huntington's disease treated with either HTT-10150 siRNA targeting full-length HTT or combination of HTT-634 and HTT-486 siRNAs targeting HTT1a 192 samples shares hippocampus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.