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Genome-wide maps of chromatin state in mouse Th17 cell [ChIP-seq]

GSE157577 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/12/31 Platform GPL21103
Summary
We applied ChIP-seq technology for mapping chromatin modification in Th17 cells. We find that acetylations on histone H3 lysine 27, an active enhancer mark, significantly overlap with open chromatin as defined by ATAC-seq. These results were used to define putative super enhancer loci in Th17 cells. Our study shows that super-enhancer mediated gene transcription is important for Th17 effector functions.
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Also filed as BioProject PRJNA661771 and SRA study SRP280292. Searching any of these in the dataset finder brings you back here.

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