GEO series

ChIP-seq of the response regulator CovR in Group B Streptococcus (GBS)

GSE158046 Streptococcus agalactiae Genome binding/occupancy profiling by high throughput sequencing 16 samples Submitted 2021/08/23 Platform GPL29157

Summary

We report the characterization of the major regulator of virulence gene expression (CovR) in Group B Streptococcus. The ChIP-seq experiments define the binding of CovR on the chromosome of the BM110 strain, a representative of the hypervirulent GBS lineage responsible of neonatal meningitis. Regulatory evolution of CovR signaling was investigated by comparing ChIP-seq done in parallel in a second GBS clinical isolate (NEM316) not belonging to the hypervirulent lineage.

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Direct links to NCBI, no account and no request form: the whole study as GSE158046_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 16 samples. Raw sequencing reads are also available from ENA.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗ Raw reads on ENA ↗

Also filed as BioProject PRJNA663857 and SRA study SRP282586. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 34491998) ↗

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