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Histone H4 is increased in SARS-CoV-2-infected lung epithelial cells and linked to COVID-19 severity

GSE167410 Homo sapiens Expression profiling by high throughput sequencing 16 samples 2025/02/24 GPL20301
Summary
We found that histone H4 is a potential biomarker of COVID-19 pathogenesis. Bulk RNA-sequencing of endothelial cell samples from idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) patients as well as controls was used in addition to published sequencing data from peripheral blood mononuclear cells or bronchoalveolar lavage fluid cells from COVID-19 and IPF patients as well as controls.
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