GEO series
Time-series transcriptomic analysis of murine colon undergoing AOM-DSS tumorigenesis with and without LXR activation
GSE180078
Mus musculus
Expression profiling by high throughput sequencing
26 samples
2024/07/19
GPL24247
Summary
To unbiasedly characterize the differentially expressed genes and pathways during colorectal cancer initiation and progression, we performed a time-series transcriptional analysis of total colonic tissue during the course of azoxymethane (AOM)-dextran sodium sulfate (DSS) induced colorectal cancer from mice receiving standard (chow) diet. Additionally, to understand the role of LXR activation during AOM-DSS tumorigenesis, we also collected colonic tissues from mice fed with GW3965 diet.
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Paper (PMID 39567700) ↗
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