Idelalisib and pneumococcal infection induce distinct transcriptional responses in mouse precision-cut lung slices
RNA-seq (gene expression) · mouse · 40 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 40 samples: 8 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE181259_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA751233 and SRA study SRP330713. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 40 samples.
How we read this: 8 replicated groups read from 40 sample titles; they account for 40 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5493677 0_1uM_IDELA_1 0_1uM_IDELA
- GSM5493678 0_1uM_IDELA_2 0_1uM_IDELA
- GSM5493679 0_1uM_IDELA_3 0_1uM_IDELA
- GSM5493680 0_1uM_IDELA_4 0_1uM_IDELA
- GSM5493681 0_1uM_IDELA_5 0_1uM_IDELA
- GSM5493682 0_1uM_IDELA_Spn_1 0_1uM_IDELA_Spn
- GSM5493683 0_1uM_IDELA_Spn_2 0_1uM_IDELA_Spn
- GSM5493684 0_1uM_IDELA_Spn_3 0_1uM_IDELA_Spn
- GSM5493685 0_1uM_IDELA_Spn_4 0_1uM_IDELA_Spn
- GSM5493686 0_1uM_IDELA_Spn_5 0_1uM_IDELA_Spn
- GSM5493687 1_0_uM_IDELA_1 1_0_uM_IDELA
- GSM5493688 1_0_uM_IDELA_2 1_0_uM_IDELA
- GSM5493689 1_0_uM_IDELA_3 1_0_uM_IDELA
- GSM5493690 1_0_uM_IDELA_4 1_0_uM_IDELA
- GSM5493691 1_0_uM_IDELA_5 1_0_uM_IDELA
- GSM5493692 1_0_uM_IDELA_Spn_1 1_0_uM_IDELA_Spn
- GSM5493693 1_0_uM_IDELA_Spn_2 1_0_uM_IDELA_Spn
- GSM5493694 1_0_uM_IDELA_Spn_3 1_0_uM_IDELA_Spn
- GSM5493695 1_0_uM_IDELA_Spn_4 1_0_uM_IDELA_Spn
- GSM5493696 1_0_uM_IDELA_Spn_5 1_0_uM_IDELA_Spn
- GSM5493697 10_uM_IDELA_1 10_uM_IDELA
- GSM5493698 10_uM_IDELA_2 10_uM_IDELA
- GSM5493699 10_uM_IDELA_3 10_uM_IDELA
- GSM5493700 10_uM_IDELA_4 10_uM_IDELA
- GSM5493701 10_uM_IDELA_5 10_uM_IDELA
- GSM5493702 10_uM_IDELA_Spn_1 10_uM_IDELA_Spn
- GSM5493703 10_uM_IDELA_Spn_2 10_uM_IDELA_Spn
- GSM5493704 10_uM_IDELA_Spn_3 10_uM_IDELA_Spn
- GSM5493705 10_uM_IDELA_Spn_4 10_uM_IDELA_Spn
- GSM5493706 10_uM_IDELA_Spn_5 10_uM_IDELA_Spn
- GSM5493707 Veh_1 Veh
- GSM5493708 Veh_2 Veh
- GSM5493709 Veh_3 Veh
- GSM5493710 Veh_4 Veh
- GSM5493711 Veh_5 Veh
- GSM5493712 Veh_Spn_1 Veh_Spn
- GSM5493713 Veh_Spn_2 Veh_Spn
- GSM5493714 Veh_Spn_3 Veh_Spn
- GSM5493715 Veh_Spn_4 Veh_Spn
- GSM5493716 Veh_Spn_5 Veh_Spn
- GSE301216 Distinct lung functional, histological and cell senescence signatures in the single vs repetitive bleomycin mouse model of idiopathic pulmonary fibrosis 53 samples shares distinct, lung
- GSE333360 Distinct neuroinflammatory effects of individual chemotherapeutics shape chemotherapy-induced peripheral neuropathy in a novel mouse model of CVAD combination regimen. 30 samples shares distinct, induce
- GSE303772 Ontogenically distinct alveolar macrophages mediate cigarette smoke-induced inflammation and damage [RNA-Seq] 24 samples shares distinct, induce
- GSE297644 Atorvastatin regulates hepatic transcriptome PXR dependently but distinct from pregnenolone 16α-carbonitrile and does not induce PXR-mediated liver steatosis 24 samples shares distinct, induce
- GSE306514 Chemokine receptor expression patterns delineate distinct interstitial macrophage subsets in the lung and define a trajectory from monocytes to mature macrophages, bulk RNA-sequencing data 24 samples shares distinct, lung
- GSE285906 Oxaliplatin induces cancer-like cachexia through distinct transcriptional pathways in mouse muscle and adipose depots 23 samples shares distinct, induce
- GSE249931 Temporal single-cell profiling of distinct mesenchymal, epithelial, endothelial, and immune cell lineages in the lung after injury 17 samples shares distinct, lung
- GSE296365 Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities 16 samples shares distinct, induce
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.