GEO series
Comparing PBMCs from patients with atopic dermatitis pre- and post-treatment with dupilumab
GSE183953
Homo sapiens
Expression profiling by high throughput sequencing
16 samples
2025/09/11
GPL24676
Summary
Atopic dermatitis (AD) is an inflammatory skin condition characterized in part by elevations in type 2 immune cytokines such as IL-4 and IL-13. Dupilumab is a monoclonal antibody that targets the shared receptor for these cytokines and has shown remarkable efficacy in reducing inflammation in AD. The goal of this study was to study the changes that occur in circulating immune cells in AD at the single cell level in response to dupilumab treatment.
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