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Targeted Manipulation of Cellular RNA m6A Methylation at the Single-Base Level

GSE185755 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/10/12 Platform GPL24676
Summary
We engineered m6A methyltransferase with dCas13-M14 to achieve site-specific editing of m6A. The resultant m6A editors can be programmed with a guide RNA, allowing functional comparison of single site methylation in different mRNA regions.
Published in
Targeted Manipulation of Cellular RNA m(6)A Methylation at the Single-Base Level
Gao M, Su S, Cao J et al. · ACS chemical biology 2022 · PMID 35294178 · doi:10.1021/acschembio.1c00895
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Also filed as BioProject PRJNA770674 and SRA study SRP341054. Searching any of these in the dataset finder brings you back here.

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