Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27-Driven Itch PathwayThe Journal of investigative dermatology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE188242_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA778002 and SRA study SRP344670. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 8 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5673270 hKCs_Ctrl_1 hKCs_Ctrl
- GSM5673271 hKCs_Ctrl_2 hKCs_Ctrl
- GSM5673272 hKCs_Ctrl_3 hKCs_Ctrl
- GSM5673273 hKCs_hIL27_1 hKCs_hIL27
- GSM5673274 hKCs_hIL27_2 hKCs_hIL27
- GSM5673275 hKCs_hIL27_3 hKCs_hIL27
- GSM5673276 mTGN_Ctrl_1 mTGN_Ctrl
- GSM5673277 mTGN_Ctrl_2 mTGN_Ctrl
- GSM5673278 mTGN_Ctrl_3 mTGN_Ctrl
- GSM5673279 mTGN_IL27_1 mTGN_IL27
- GSM5673280 mTGN_IL27_2 mTGN_IL27
- GSM5673281 mTGN_IL27_3 mTGN_IL27
- GSM5673282 ctrl_6h_1 ctrl_6h
- GSM5673283 ctrl_6h_2 ctrl_6h
- GSM5673284 ctrl_6h_3 ctrl_6h
- GSM5673285 BST2_24h_1 BST2_24h
- GSM5673286 BST2_24h_2 BST2_24h
- GSM5673287 BST2_24h_3 BST2_24h
- GSM5673288 TGN_6h_Ctrl1 TGN_6h_Ctrl
- GSM5673289 TGN_6h_Ctrl2 TGN_6h_Ctrl
- GSM5673290 TGN_6h_Ctrl3 TGN_6h_Ctrl
- GSM5673291 TGN_6_BST2_1 TGN_6_BST2
- GSM5673292 TGN_6_BST2_2 TGN_6_BST2
- GSM5673293 TGN_6_BST2_3 TGN_6_BST2
No close match found for this topic, so these are simply the most-viewed datasets of the same kind.
- GSE317764 High-Fat Diet Causes Rapid Loss of Intestinal Group 3 Innate Lymphoid Cells Through Microbiota-Driven Inflammation 270 samples
- GSE341321 Vitamin B2 Sensing by the Nuclear Receptor AhR Reprograms Hepatic Metabolism [RNA-Seq] 100 samples
- GSE292302 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: RNA-seq 42 samples
- GSE315101 Soluble DLK1 secreted by telomere-shortening-induced senescent microglia impairs oligodendrocyte functions and alters neuronal activity [DLK1_snRNA-seq] 27 samples
- GSE254156 The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumor suppression 25 samples
- GSE330200 The p.Ser143Pro lamin A/C mutation leads to dilated cardiomyopathy and activates the unfolded protein response pathway in a knock-in mouse model 19 samples
- GSE291551 Analysis of individual patient pathway coordination in a cross-species single-cell kidney atlas 11 samples
- GSE289420 Astrocyte-derived cholesterol drives synaptic gene expression in developing neurons and reciprocal astrocytic transcriptional programs 416 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.