GEO series
Primary human hepatocyte transcriptomic statin response
GSE191092
Homo sapiens
Expression profiling by high throughput sequencing
11 samples
2024/12/16
GPL11154
Summary
We have previously identified a number of statin-responsive genes in human cell lines, but in some cases, these findings may not be relevant in vivo. Here, we statin exposed primary human hepatocytes from four different donors to identify statin-responsive genes in this biologically relevant cell type. We also compared the effects of statin on gene expression between these primary cells and our previous datasets in other cell lines to identify overlapping effects of interest.
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