TTFields plus TMZ treatment effects on newly diagnosed Glioblastoma patients in peripheral blood
Single-cell RNA-seq · human · 24 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Homo sapiens (human)
- Topic
- GlioblastomaThis series is part of our curated briefing on it.
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE193525_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA796536 and SRA study SRP354644. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5813657 PBMC of patient #7 before TTF treatment
- GSM5813658 PBMC of patient #7 after TTF treatment
- GSM5813659 PBMC of patient #9 before TTF treatment
- GSM5813660 PBMC of patient #9 after TTF treatment
- GSM5813661 PBMC of patient #14 before TTF treatment
- GSM5813662 PBMC of patient #14 after TTF treatment
- GSM5813663 PBMC of patient #16 before TTF treatment
- GSM5813664 PBMC of patient #16 after TTF treatment
- GSM5813665 PBMC of patient #12 before TTF treatment
- GSM5813666 PBMC of patient #12 after TTF treatment
- GSM5813667 PBMC of patient #18 before TTF treatment
- GSM5813668 PBMC of patient #18 after TTF treatment
- GSM5813669 PBMC of patient #19 before TTF treatment
- GSM5813670 PBMC of patient #19 after TTF treatment
- GSM5813671 PBMC of patient #22 before TTF treatment
- GSM5813672 PBMC of patient #22 after TTF treatment
- GSM5813673 PBMC of patient #23 before TTF treatment
- GSM5813674 PBMC of patient #23 after TTF treatment
- GSM5813675 PBMC of patient #24 before TTF treatment
- GSM5813676 PBMC of patient #24 after TTF treatment
- GSM5813677 PBMC of patient #25 before TTF treatment
- GSM5813678 PBMC of patient #25 after TTF treatment
- GSM5813679 PBMC of patient #28 before TTF treatment
- GSM5813680 PBMC of patient #28 after TTF treatment
- GSE112648 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 18 samples same disease briefing · shares glioblastoma
- GSE131928 single cell RNA-seq analysis of adult and paediatric IDH-wildtype Glioblastomas 2 samples same disease briefing · shares glioblastoma
- GSE107560 Ivy Glioblastoma Atlas Project 305 samples same disease briefing · shares glioblastoma
- GSE13041 Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age 267 samples same disease briefing · shares glioblastoma
- GSE10878 Integrative Genome-wide Analysis of Glioblastoma. 60 samples same disease briefing · shares glioblastoma
- GSE112650 SOX4/11 Enhances NGN2 Reprogramming Glioblastoma Cells into Neuron Cells by Modulating RhoA and CDC42/RAC1 Pathway Activity 30 samples same disease briefing · shares glioblastoma
- GSE112645 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 12 samples same disease briefing · shares glioblastoma
- GSE115459 Exosome-transmitted RVT1 from reactive astrocytes promotes recurrence glioblastoma proliferation 9 samples same disease briefing · shares glioblastoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.