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Human bladder cancer cell line high throughput sequencing - genes regulated by hMSH2 - CDDP therapy

GSE193753 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/06/20 Platform GPL24676
Summary
The activation status of some DNA damage repair proteins is closely related to the efficacy of CDDP chemotherapy in MIBC. In this study, we used CRISPR/cas9 gene-editing technology to construct hMSH2-deficient bladder cancer cells and confirmed that loss of hMSH2 decreased the sensitivity of bladder cancer cells to cisplatin. Transcriptome analysis was performed to find the potential genes that could be regulated by hMSH2.
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Direct links to NCBI, no account and no request form: the whole study as GSE193753_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA797652. Searching any of these in the dataset finder brings you back here.

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