Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling
RNA-seq (gene expression) · human · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 16 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signallingCell communication and signaling : CCS · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE199628_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA820866 and SRA study SRP366379. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 16 more — browse all 16 samples with per-sample file links →
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- GSE289930 Proteogenomic Characterization of Primary Oral Cancer Unveils Extracellular Matrix Remodeling and Immunosuppressive Microenvironment Linked to Lymph Node Metastasis [RNA-seq] 33 samples shares metastasis, primary
- GSE277742 Immune Landscape of Intrathoracic Lymph Nodes with Metastasis in Primary Lung Malignancy using EBUS-TBNA samples 22 samples shares metastasis, primary
- GSE222467 The RNA binding proteins LARP4A and LARP4B promote tumour growth and metastasis in prostate cancer and osteosarcoma 12 samples shares metastasis, growth
- GSE281450 LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment 12 samples shares metastasis, growth
- GSE224495 Differential LncRNA expression of 5 primary ovarian tumors and matched metastasis 10 samples shares metastasis, primary
- GSE277337 MICAL2 Is a Super Enhancer Associated Gene that Promotes Pancreatic Cancer Growth and Metastasis 26 samples shares metastasis, growth
- GSE273244 BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence 80 samples shares bmp4
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.