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shRNA-mediated knockdown of PRMT5 gene in LNCaP cells

GSE206111 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/06/13 Platform GPL16791
Summary
We performed shRNA-mediated knockdown of PRMT5 in LNCaP cells via dox-inducible expression system. We sought to compare transcriptome with- and without PRMT5 knockdown across three biological replicates
Published in
Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors
Asberry AM, Cai X, Deng X et al. · Journal of medicinal chemistry 2022 · PMID 36206451 · doi:10.1021/acs.jmedchem.2c01000
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Also filed as BioProject PRJNA849221 and SRA study SRP380214. Searching any of these in the dataset finder brings you back here.

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