Transcriptome profile of thioacetamide treated mice injected with AAV8 TBG eGFP and AAV8 TBG miR34b/c
RNA-seq (gene expression) · mouse · 19 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples: 7 × TAA_GFP vs 7 × TAA_mi vs 5 × PBSGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hepatocyte delivery of miR-34b/c reduces hepatic stellate cell activation and improves liver fibrosisMolecular therapy. Nucleic acids · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE206761_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA852086 and SRA study SRP383288. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 3 replicated groups read from 19 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6261919 PBS_1 PBS
- GSM6261920 PBS_2 PBS
- GSM6261921 PBS_3 PBS
- GSM6261922 PBS_4 PBS
- GSM6261923 PBS_5 PBS
- GSM6261924 TAA_GFP_1 TAA_GFP
- GSM6261925 TAA_GFP_2 TAA_GFP
- GSM6261926 TAA_GFP_3 TAA_GFP
- GSM6261927 TAA_GFP_4 TAA_GFP
- GSM6261928 TAA_GFP_5 TAA_GFP
- GSM6261929 TAA_GFP_6 TAA_GFP
- GSM6261930 TAA_GFP_7 TAA_GFP
- GSM6261931 TAA_miR_1 TAA_mi
- GSM6261932 TAA_miR_2 TAA_mi
- GSM6261933 TAA_miR_3 TAA_mi
- GSM6261934 TAA_miR_4 TAA_mi
- GSM6261935 TAA_miR_5 TAA_mi
- GSM6261936 TAA_miR_6 TAA_mi
- GSM6261937 TAA_miR_7 TAA_mi
- GSE275896 RNA-Seq of Primary HSCs of Wild-type and Cyp1b1 Knockout Mice with Thioacetamide Treatment 4 samples shares thioacetamide
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.