Estrogen alleviates acute and chronic itch in mice
RNA-seq (gene expression) · mouse · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 23 samples: 5 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE207174_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA854054 and SRA study SRP384167. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 23 samples.
How we read this: 5 replicated groups read from 23 sample titles; they account for 23 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6280798 A1 A
- GSM6280799 A2 A
- GSM6280800 A3 A
- GSM6280801 A4 A
- GSM6280802 V1 V
- GSM6280803 V3 V
- GSM6280804 V4 V
- GSM6280805 H1 H
- GSM6280806 H2 H
- GSM6280807 H3 H
- GSM6280808 H4 H
- GSM6280809 H5 H
- GSM6280810 A_01 A
- GSM6280811 A_02 A
- GSM6280812 A_04 A
- GSM6280813 O2 O
- GSM6280814 O4 O
- GSM6280815 O5 O
- GSM6280816 CONTROL1 CONTROL
- GSM6280817 CONTROL2 CONTROL
- GSM6280818 CONTROL3 CONTROL
- GSM6280819 CONTROL4 CONTROL
- GSM6280820 CONTROL5 CONTROL
- GSE314324 Transcriptomic responses to acute or chronic ethanol exposure observed across five brain regions in male mice 62 samples shares chronic, acute
- GSE254360 Single-nucleus transcriptomic analysis of the amygdala of mice in acute and chronic neuropathic pain 15 samples shares chronic, acute
- GSE276647 Gene expression profile of microglia following traumatic brain injury and nasal anti-CD3 treatment at acute and chronic timepoints 54 samples shares chronic, acute
- GSE333494 Hippocampal CA3 Nex+ neuronal TNFR2 alleviates chronic neuropathic pain by sex-dependently engaging opioid and endocannabinoid pathways 26 samples shares alleviates, chronic
- GSE239287 Single-cell transcriptome sequencing of macrophages in acute kidney injury(AKI) to chronic kidney dieases(CKD) 17 samples shares chronic, acute
- GSE264408 Single-cell RNA sequencing of healthy mouse colon and mouse colon with acute or chronic colitis induced by DSS 10 samples shares chronic, acute
- GSE341526 Atractylenolide III Alleviates Cisplatin-Induced Acute Liver Injury by Regulating Gut-Liver Axis Through Inhibiting ACT1/TRAF6/NF-κB-Mediated IL-17 Pathway 9 samples shares alleviates, acute
- GSE313359 Hippocampal estrogen levels, receptor types and epigenetics contribute to sex-specific memory-vulnerabilities to concurrent acute stresses [Cut & Run] 45 samples shares estrogen, acute
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.