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Understanding early human knee joint development with a single cell RNAseq approach

GSE209948 Homo sapiens Expression profiling by high throughput sequencing 5 samples Submitted 2025/07/28 Platform GPL24676
Summary
Mature synovial joints consist of cruciate ligament, articular cartilage, superficial membrane and mensicus. During limb development, all these structures are developed from a transient joint anlagen called the interzone. Studies in mouse are relatively well established but less imformation is available for human joint. This study captured progenitors and committed joint and surrounding growth plate cartilage from 4 human fetuses (from 9w to 18wk gestation time).
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Direct links to NCBI, no account and no request form: the whole study as GSE209948_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA863129 and SRA study SRP388558. Searching any of these in the dataset finder brings you back here.

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