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Identification of formononetin as the active compound of CR-SR in hepatocellular carcinoma treatment: An integrated approach combining network pharmacology and weighted gene co-expression networks

GSE210739 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/08/31 Platform GPL24676
Summary
Curcumae Rhizoma and Sparganii Rhizoma (CR-SR) is a classic herbal combination for treating HCC in China. Formononetin is the main active ingredient in CR-SR. To understand the pharmacological properties of formononetin, human hepatoma HepG2 cells were stimulated with or without 625μM formononetin for 72 h. Then, total RNA was extracted for gene expression profile analysis.
Published in
Identification of formononetin as the active compound of CR-SR in hepatocellular carcinoma treatment: An integrated approach combining network pharmacology and weighted gene co-expression networks
Li C, Xie Y, Hu S et al. · Chemical biology & drug design 2024 · PMID 37793997 · doi:10.1111/cbdd.14363
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Also filed as BioProject PRJNA867348 and SRA study SRP390505. Searching any of these in the dataset finder brings you back here.

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