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RNA polymerase II binding profile in WT and MED23-KD 293T cells

GSE211084 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/05/28 Platform GPL24676
Summary
MED23-KD 293T cells in which MED23 was mostly knockouted were generated by CRISPR-Cas9. We performed CUT&Tag experiments in WT and MED23-KD cells to characterize the change of Pol II binding.
Published in
Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3' end processing factors
Lu C, Bai X, Zhang H et al. · Molecular cell 2025 · PMID 40441154 · doi:10.1016/j.molcel.2025.05.006
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Also filed as BioProject PRJNA868783 and SRA study SRP391155. Searching any of these in the dataset finder brings you back here.

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