Elimination of dormant cancer stem cells by disrupting glucocorticoid mediated lipid metabolism in glioblastoma
RNA-seq (gene expression) · human · 59 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- GlioblastomaThis series is part of our curated briefing on it.
- Samples
- 59 samples: 11 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE215245_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA889416 and SRA study SRP401141. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 37 samples.
How we read this: 11 replicated groups read from 59 sample titles; they account for 37 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6616798 601-CON-1 601-CON
- GSM6616799 601-CON-2 601-CON
- GSM6616800 601-CON-3 601-CON
- GSM6616801 601-DEX-1 601-DEX
- GSM6616802 601-DEX-2 601-DEX
- GSM6616803 601-DEX-3 601-DEX
- GSM6616804 601-MIF-1 601-MIF
- GSM6616805 601-MIF-2 601-MIF
- GSM6616806 601-MIF-3 601-MIF
- GSM6616807 601GPDKO53-1 601GPDKO53
- GSM6616808 601GPDKO53-2 601GPDKO53
- GSM6616809 601GPDKO53-3 601GPDKO53
- GSM6616810 711-CON-1 711-CON
- GSM6616811 711-CON-2 711-CON
- GSM6616812 711-CON-3 711-CON
- GSM6616813 711-DEX-1 711-DEX
- GSM6616814 711-DEX-2 711-DEX
- GSM6616815 711-DEX-3 711-DEX
- GSM6616816 711-MIF-1 711-MIF
- GSM6616817 711-MIF-2 711-MIF
- GSM6616818 711-MIF-3 711-MIF
- GSM6616819 711GRKO-1 711GRKO
- GSM6616820 711GRKO-2 711GRKO
- GSM6616821 711GRKO-3 711GRKO
- GSM6630277 DMSO_1 DMSO
- GSM6630278 DMSO_2 DMSO
- GSM6630279 DMSO_3 DMSO
- GSM6630280 DEXA_4 DEXA
- GSM6630281 DEXA_5 DEXA
- GSM6630282 DEXA_6 DEXA
- GSM6630283 DEXA_7 DEXA
- GSM6630284 DEXA_8 DEXA
- GSM6630285 MIFE_9 MIFE
- GSM6630286 MIFE_10 MIFE
- GSM6630287 MIFE_11 MIFE
- GSM6630288 MIFE_12 MIFE
- GSM6630289 MIFE_13 MIFE
- GSM6630290 NCH601-GPD1-sh3-1d
- GSM6630291 NCH601-GPD1-sh3-2d
- GSM6630292 NCH601-GPD1-sh3-3d
+ 19 more — browse all 59 samples with per-sample file links →
- GSE112648 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 18 samples same disease briefing · shares glioblastoma
- GSE131928 single cell RNA-seq analysis of adult and paediatric IDH-wildtype Glioblastomas 2 samples same disease briefing · shares glioblastoma
- GSE107560 Ivy Glioblastoma Atlas Project 305 samples same disease briefing · shares glioblastoma
- GSE13041 Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age 267 samples same disease briefing · shares glioblastoma
- GSE10878 Integrative Genome-wide Analysis of Glioblastoma. 60 samples same disease briefing · shares glioblastoma
- GSE112650 SOX4/11 Enhances NGN2 Reprogramming Glioblastoma Cells into Neuron Cells by Modulating RhoA and CDC42/RAC1 Pathway Activity 30 samples same disease briefing · shares glioblastoma
- GSE112645 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 12 samples same disease briefing · shares glioblastoma
- GSE115459 Exosome-transmitted RVT1 from reactive astrocytes promotes recurrence glioblastoma proliferation 9 samples same disease briefing · shares glioblastoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.