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The intrinsically disordered region of SPIN1 regulates its function by phase separation [ChIP-seq]

GSE215398 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2024/12/19 Platform GPL24676
Summary
As a transcriptional coactivator, SPIN1 has been reported to bind to chromatin.To assess the effect of IDR on chromatin binding, we investigated genome-wide chromatin association of SPIN1-WT or SPIN1-△IDR stably overexpressed cell lines by chromatin immunoprecipitation followed by high-throughput sequencing.
Published in
Phase separation of SPIN1 through its IDR facilitates histone methylation readout and tumorigenesis
Wang Y, Chen Y, Li M et al. · Journal of molecular cell biology 2024 · PMID 38777743 · doi:10.1093/jmcb/mjae024
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Also filed as BioProject PRJNA890209 and SRA study SRP402398. Searching any of these in the dataset finder brings you back here.

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