GEO series
Global and region-specific rules of airway epithelial development
GSE215957
Mus musculus
Expression profiling by high throughput sequencing
478 samples
2026/02/16
GPL17021
Summary
Lineage tracing experiment using a airway secretory specific Cre driver mouse. Airway secretory (club) cells were labelled from the beginning of the expression of the pansecretory marker Scgb1a1, at embryonic day 16.5 (E16.5) and samples were collected in four developmental stages (E19.5, P2, P21 and P60). Samples were collected right before activation of the Cre reporter, at E16.5, and served as control. We were interested to characterize the transcriptomic changes and uncover the molecular mechanisms that control the differentiation and maturation of the secretory cell lineage.
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