GEO series
Post stimulation immune response in suspected ZC3H12A deficiency
GSE215999
Homo sapiens
Expression profiling by high throughput sequencing
158 samples
2025/01/31
GPL20301
Summary
ZC3H12A deficiency has not been reported in humans yet but mechanistic in vitro as well as mouse study data show strong evidence that ZC3H12A acts as a negative immune regu;ator This series contains RNA sequencing data from primary fibroblasts obtained from patients with DBR1 deficiency, including mock-treated vs virus-infected cells. Cells from healthy unrelated controls and patients with STAT1 or TLR3 deficiency were analyzed for comparison.
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