GEO series
Impact of sunitinib resistance on clear cell renal cell carcinoma therapeutic sensitivity in vitro
GSE216494
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/04/17
GPL11154GPL24676
Summary
Sunitinib resistance creates a major clinical challenge for the treatment of advanced clear cell renal cell carcinoma (ccRCC) and functional and metabolic changes linked to sunitinib resistance are not fully understood. We sought to characterize the molecular and metabolic changes induced by the development of sunitinib resistance in ccRCC by developing and characterizing the transcriptome of two human ccRCC cell lines resistant to sunitinib.
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Paper (PMID 38263737) ↗
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