GEO series
Mapping Individual Chemoresistome in Breast Cancer Patients Unravels Diversity in Dynamic Transcriptional Adaptation
GSE217624
Homo sapiens
Expression profiling by high throughput sequencing
84 samples
2025/11/01
GPL20301
Summary
Tumors are continuously evolving through their course of progression and treatment, a major process contributing to resistance to therapy. Recent studies brought into focus the importance of non-genetic adaptive mechanisms, by which tumors acquire resistance via rewiring transcriptional programs. To dissect these adaptive processes in the individual breast cancer patients, we combined longitudinal transcriptomics with temporal pattern analysis.
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Paper (PMID 40294066) ↗
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