GEO series
Fosl2 overexpression and Ezh2 inhibition in mouse embryonic fibroblasts
GSE217780
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
15 samples
2024/07/15
GPL30172
Summary
To assess the impact of AP-1 chromatin remodelling, we over-expressed one AP-1 family member, namely Fra2 (encoded by Fosl2), in mouse embryonic fibroblasts (MEFs). To assess the impact of general chromatin depression, we inhibited the activity of PRC2 component histone-lysine N-methyltransferase Ezh2 in MEFS.
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Paper (PMID 38959897) ↗
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