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Genome-wide maps of chromatin state in thymocytes from Nsd2-edited mice

GSE220890 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 7 samples Submitted 2024/04/01 Platform GPL17021
Summary
We performed high-throughput profiling of histone modifications in mouse thymocytes in which Nsd2 were deleted (KO) or Nsd2 were substituted as following c.2717C>T; p.Pro906Leu that is an orthologous substitution of human NSD2 c.2714C>T; p.Pro905Leu (KI). We found that lysine 36 dimethylation were generally decreased in KO and KI. These were associated with regulation of gene expression.
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Also filed as BioProject PRJNA913158 and SRA study SRP413461. Searching any of these in the dataset finder brings you back here.

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