Plasma multi-omics identify early pathogenesis and biomarkers of SCD post-AMI
RNA-seq (gene expression) · human · 106 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 106 samples: 53 × SCD post AMI, D vs 53 × Survivor post AMI, SGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- S100a9 lactylation triggers neutrophil trafficking and cardiac inflammation in myocardial ischemia/reperfusion injuryThe Journal of clinical investigation · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE221740_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA915943 and SRA study SRP414823. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 106 samples.
How we read this: 2 replicated groups read from 106 sample titles; they account for 106 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6894047 SCD post AMI, D1 SCD post AMI, D
- GSM6894048 Survivor post AMI, S1 Survivor post AMI, S
- GSM6894049 SCD post AMI, D2 SCD post AMI, D
- GSM6894050 Survivor post AMI, S2 Survivor post AMI, S
- GSM6894051 SCD post AMI, D3 SCD post AMI, D
- GSM6894052 Survivor post AMI, S3 Survivor post AMI, S
- GSM6894053 SCD post AMI, D4 SCD post AMI, D
- GSM6894054 Survivor post AMI, S4 Survivor post AMI, S
- GSM6894055 SCD post AMI, D5 SCD post AMI, D
- GSM6894056 Survivor post AMI, S5 Survivor post AMI, S
- GSM6894057 SCD post AMI, D6 SCD post AMI, D
- GSM6894058 Survivor post AMI, S6 Survivor post AMI, S
- GSM6894059 SCD post AMI, D7 SCD post AMI, D
- GSM6894060 Survivor post AMI, S7 Survivor post AMI, S
- GSM6894061 SCD post AMI, D8 SCD post AMI, D
- GSM6894062 Survivor post AMI, S8 Survivor post AMI, S
- GSM6894063 SCD post AMI, D9 SCD post AMI, D
- GSM6894064 Survivor post AMI, S9 Survivor post AMI, S
- GSM6894065 SCD post AMI, D10 SCD post AMI, D
- GSM6894066 Survivor post AMI, S10 Survivor post AMI, S
- GSM6894067 SCD post AMI, D11 SCD post AMI, D
- GSM6894068 Survivor post AMI, S11 Survivor post AMI, S
- GSM6894069 SCD post AMI, D12 SCD post AMI, D
- GSM6894070 Survivor post AMI, S12 Survivor post AMI, S
- GSM6894071 SCD post AMI, D13 SCD post AMI, D
- GSM6894072 Survivor post AMI, S13 Survivor post AMI, S
- GSM6894073 SCD post AMI, D15 SCD post AMI, D
- GSM6894074 Survivor post AMI, S15 Survivor post AMI, S
- GSM6894075 SCD post AMI, D16 SCD post AMI, D
- GSM6894076 Survivor post AMI, S16 Survivor post AMI, S
- GSM6894077 SCD post AMI, D17 SCD post AMI, D
- GSM6894078 Survivor post AMI, S17 Survivor post AMI, S
- GSM6894079 SCD post AMI, D18 SCD post AMI, D
- GSM6894080 Survivor post AMI, S18 Survivor post AMI, S
- GSM6894081 SCD post AMI, D19 SCD post AMI, D
- GSM6894082 Survivor post AMI, S19 Survivor post AMI, S
- GSM6894083 SCD post AMI, D20 SCD post AMI, D
- GSM6894084 Survivor post AMI, S20 Survivor post AMI, S
- GSM6894085 SCD post AMI, D21 SCD post AMI, D
- GSM6894086 Survivor post AMI, S21 Survivor post AMI, S
+ 66 more — browse all 106 samples with per-sample file links →
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.