Long Noncoding RNA LIRIL2R Modulates FOXP3 Levels and Suppressive Function of Human CD4+ Regulatory T Cells by Regulating IL2RA
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 94 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 94 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4(+) regulatory T cells by regulating IL2RAProceedings of the National Academy of Sciences of the United States of America · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE221759_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA915965 and SRA study SRP414840. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 94 more — browse all 94 samples with per-sample file links →
- GSE314342 Genome-scale perturb-seq in primary human CD4+ T cells reveals genes regulating T cell programs and human immune traits. 577 samples shares cd4, regulating
- GSE282496 CD38 expression by neonatal human naïve CD4+ T cells shapes their unique metabolic state and high regulatory T cell potential 41 samples shares cd4, regulatory
- GSE307831 Human peripheral and tissue Foxp3-high regulatory T cells in patients with hepatocellular carcinoma [CITE-seq] 33 samples shares foxp3, regulatory
- GSE264191 Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 and CD44 through NFκB signaling 30 samples shares cd4, regulating
- GSE285773 Single cell RNA profiling of blood CD4+ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE [CD4+ T cells] 26 samples shares cd4, regulatory
- GSE286472 FOXP3 Expression Depends on Cell-Type Specific Cis-Regulatory Element and Transcription Factor Circuitry [human_Treg_ChIP-seq] 18 samples shares foxp3, regulatory
- GSE251851 Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 and CD44 through NFκB signaling [LNCaP] 18 samples shares cd4, regulating
- GSE309709 Three immunoregulatory signatures define non-productive HIV infection in stem cell memory CD4+ T cells 16 samples shares cd4, regulatory
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.