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Assessment of ‘molecular organ age’ in pre-transplant kidney biopsies

GSE222868 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2024/08/16 Platform GPL20301
Summary
Clinical kidney biopsies variably contain cortex and medulla depending on biopsy depth and angle. Therefore, biopsy composition may alter the transcriptional profile and confound conclusions drawn from differential gene expression analysis. To account for this in retrieval biopsies, we assessed differences in gene expression between paired cortex and medulla samples in n=5 human kidneys.
Published in
Assessment of biological organ age using molecular pathology in pre-transplant kidney biopsies
Zhang R, Trotter PB, McCaffrey J et al. · Kidney international 2024 · PMID 38692408 · doi:10.1016/j.kint.2024.03.028
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Also filed as BioProject PRJNA923683 and SRA study SRP417420. Searching any of these in the dataset finder brings you back here.

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