← BioTransfer GEO Dataset Finder
GEO series

Single cell ATAC-seq analysis of human dermal fibroblasts and human pluripotent stem cells

GSE224699 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2024/05/01 Platform GPL16791
Summary
Human pluripotent stem cells have two major pluripotent states, primed and naive, and the heterogeneity among cell lines in each pluripotent state remains a major unresolved problem. We showed that the overexpression of H1FOO-DD, which has a short expression period by fusing the destabilized domain to the maternal-specific linker histone H1FOO, together with OCT4, SOX2, KLF4 and LMYC in human somatic cells improves the quality of reprogramming to primed and naive pluripotency.
Published in
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency
Kunitomi A, Hirohata R, Osawa M et al. · Stem cell reports 2024 · PMID 38701780 · doi:10.1016/j.stemcr.2024.04.005
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE224699_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA932225 and SRA study SRP421310. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 8 more — browse all 8 samples with per-sample file links →

Similar datasets

Search all human ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.